Grants

Canadian Space Agency | Agence spatiale canadienne

Reports on Plans and Priorities (RPPs) are individual expenditure plans for each department and agency (excluding Crown corporations). These reports provide increased levels of detail over a three-year period on an organization's main priorities by strategic outcome(s), program activity(ies) and planned/expected results, including links to related resource requirements. The RPPs also provide details on human resource requirements, major capital projects, grants and contributions, and net program costs. They are tabled in Parliament by the President of the Treasury Board on behalf of the ministers who preside over the appropriation-dependent departments and agencies identified in Schedules I, I.1 and II of the Financial Administration Act . These documents are usually tabled on or before March 31 and referred to committees, which may then report to the House of Commons pursuant to Standing Order 81(7).

Canadian Space Agency | Agence spatiale canadienne

Reports on Plans and Priorities (RPPs) are individual expenditure plans for each department and agency (excluding Crown corporations). These reports provide increased levels of detail over a three-year period on an organization's main priorities by strategic outcome(s), program activity(ies) and planned/expected results, including links to related resource requirements. The RPPs also provide details on human resource requirements, major capital projects, grants and contributions, and net program costs. They are tabled in Parliament by the President of the Treasury Board on behalf of the ministers who preside over the appropriation-dependent departments and agencies identified in Schedules I, I.1 and II of the Financial Administration Act . These documents are usually tabled on or before March 31 and referred to committees, which may then report to the House of Commons pursuant to Standing Order 81(7).

Canadian Space Agency | Agence spatiale canadienne

Reports on Plans and Priorities (RPPs) are individual expenditure plans for each department and agency (excluding Crown corporations). These reports provide increased levels of detail over a three-year period on an organization's main priorities by strategic outcome(s), program activity(ies) and planned/expected results, including links to related resource requirements. The RPPs also provide details on human resource requirements, major capital projects, grants and contributions, and net program costs. They are tabled in Parliament by the President of the Treasury Board on behalf of the ministers who preside over the appropriation-dependent departments and agencies identified in Schedules I, I.1 and II of the Financial Administration Act . These documents are usually tabled on or before March 31 and referred to committees, which may then report to the House of Commons pursuant to Standing Order 81(7).

Canadian Space Agency | Agence spatiale canadienne

Reports on Plans and Priorities (RPPs) are individual expenditure plans for each department and agency (excluding Crown corporations). These reports provide increased levels of detail over a three-year period on an organization's main priorities by strategic outcome(s), program activity(ies) and planned/expected results, including links to related resource requirements. The RPPs also provide details on human resource requirements, major capital projects, grants and contributions, and net program costs. They are tabled in Parliament by the President of the Treasury Board on behalf of the ministers who preside over the appropriation-dependent departments and agencies identified in Schedules I, I.1 and II of the Financial Administration Act . These documents are usually tabled on or before March 31 and referred to committees, which may then report to the House of Commons pursuant to Standing Order 81(7).

Canadian Space Agency | Agence spatiale canadienne

Departmental Plans (DPs) and Reports on Plans and Priorities (RPPs) are individual expenditure plans for each department and agency (excluding Crown corporations). These reports provide increased levels of detail over a three-year period on an organization's main priorities by strategic outcome(s), program activity(ies) and planned/expected results, including links to related resource requirements. The RPPs also provide details on human resource requirements, major capital projects, grants and contributions, and net program costs. They are tabled in Parliament by the President of the Treasury Board on behalf of the ministers who preside over the appropriation-dependent departments and agencies identified in Schedules I, I.1 and II of the Financial Administration Act . These documents are usually tabled on or before March 31 and referred to committees, which may then report to the House of Commons pursuant to Standing Order 81(7).

Canadian Tire Corporation

Jumpstart helps kids in need participate in organized sports and recreation by providing grants to families and community organizations.

Market NY - RC5 - EDF

Canadian Visitation 2016 Working Capital

Canadian Women's Foundation

Funds programs that address gender-based violence, economic development for women, and girls' empowerment across Canada.

Canajoharie Central School District

Canajoharie/Ft. Plain CSD Merger Study

NSF

All living organisms rely on interacting networks of genes to carry out vital functions like growth, development, and response to the environment. These networks must operate reliably even in the face of unpredictable changes, such as random mutations or environmental shifts. One key to that stability is a biological concept called canalization. This project investigates how gene regulatory networks (GRNs) achieve such stability by studying how their structure shapes their behavior. Using simple but powerful mathematical models, the research will uncover underlying design principles that make these networks robust. To achieve this, the project will analyze hundreds of previously published expert-curated GRN models using new computational tools and theoretical insights. The findings will be validated through biological experiments in a model plant species, Arabidopsis. The broader impacts of this project include the creation of public databases and software tools that will allow scientists to explore how gene networks function. By involving students in all aspects of the research, this project contributes to the interdisciplinary training of the STEM workforce. Moreover, this project has the potential to support efforts in agriculture, biology and medicine by helping scientists better understand how genetic systems function and maintain their resilience. This project seeks to elucidate design principles of GRNs using discrete dynamical systems, specifically Boolean and multistate network models. The central focus is on the biological concept of canalization, which refers to the process of creating stability in a gene regulation program despite genetic and environmental variability. This project will develop a biologically meaningful definition of canalization for multistate functions. A meta-analysis of all published, expert-curated discrete GRN models will be conducted to identify structural and dynamical features that are overrepresented compared to random expectations, including canalization, redundancy, and long-term dynamic behavior. To assess the functional relevance of identified design principles, GRNs with varying properties will be simulated, and dynamical outcomes, such as robustness and phenotypic switching, will be measured. Analysis methods will be implemented in open-source software tools, integrated with existing software libraries such as CANA and BooleanNet. Experimental validation will be performed using Arabidopsis root GRNs, revealing biological insights into correlations between phenotypes, transcription factor expression levels and root GRN robustness. This multi-faceted approach combining theory, computation, and experiment will yield new insights into how GRN topology governs dynamics and how stability is achieved through canalization and other structural features. This award reflects NSF's statutory mission and has been deemed worthy of support through evaluation using the Foundation's intellectual merit and broader impacts review criteria.

Regional Council Capital Fund - RC4

Canandaigua Lake Development

National Institutes of Health

Cancer Center Support Grants (CCSGs) for NCI-designated Cancer Centers (P30 Clinical Trial Optional)

NCI - National Cancer Institute

Endometrial cancer (EC) is increasing in frequency and mortality and harbors one of the largest health disparities in US cancers. To address this disparity, we propose the Cancer Health Disparities SPORE in Endometrial Cancer that is comprised of a multi-disciplinary translational research team and a comprehensive approach to studying disparities in EC that incorporates both social and biological factors into the study design of each of our three Projects and makes use of three unique EC patient cohorts as well as novel pre-clinical mouse and organoid models. The overall mission of our SPORE is to define key biological factors (epigenetic aging in Project 1; microbiome and innate immunity in Project 2; metabolic reprogramming and allostatic load in Project 3) alongside measurable social factors that may drive more aggressive behavior or lead to worse EC outcomes (treatment response, survival). Our hypothesis is that disparities influencing social and biological factors are fundamental drivers of poorer outcomes for women with EC, including the inter-related biological factors of epigenetic age acceleration, microbial dysbiosis, a heightened innate immune system, metabolic reprogramming and increased allostatic load. To address this hypothesis, we will leverage the on-going Carolina Endometrial Cancer Study (CECS) as our first patient cohort, a NC state-wide population-based prospective study of >1,700 EC patients with survey and medical records data collection, acquisition of tumor samples, and ongoing follow-up to collect data on treatment response and survival. CECS integrates tumor biology with measurable clinical and social data as potential contributors to worse outcomes in EC patients, and this study is central to Projects 1 and 2. In addition, we will make use of a second patient cohort which is a prospective study of EC patients undergoing programmed cell death protein-1 (PD-1) inhibitor immunotherapy treatment (PROMOTE) and includes the collection of tumors, blood, rectal swabs and stool, which are to be analyzed in Project 2. Our third patient cohort consists of banked tumor/blood from EC patients at both UNC and MD Anderson for analysis in Project 3. To complement these patient cohorts, we plan more mechanistic studies in pre-clinical models, including a unique germ-free EC mouse model (Project 2) and EC organoids (Project 3). These three Projects are supported by four integrated Cores, including an Administrative Core, a Biospecimens/Pathology Core, a Biostatistics/Bioinformatics Core and a Community Outreach and Engagement Core as well as a Developmental Research Program and Career Enhancement Program for the next generation of ideas and investigators. By combining these three Projects into a single program that share both key resources (patient cohorts, four Cores) and critical clinical, social and biological measures, we will identify the most impactful factors for biomarker and therapeutic target development and immediate translation into clinical interventions to improve outcomes in EC patients.

NCI - National Cancer Institute

Project Summary/Abstract The goal of our proposed Data and Resource Coordinating Center (DRCC) application is to catalyze collaboration across the Cancer Immunoprevention Network (CIP-Net) and to manage, integrate and disseminate the data and resources generated through the network. By leveraging cutting-edge, multidisciplinary team approaches, we will support CIP-Net in fostering a collaborative community of cancer immunoprevention researchers, collectively working to understand the basic mechanisms of immunoprevention, discover novel immunoprevention strategies, and develop and test preclinical interventions. Our strategy is to boost the productivity of CIP-Net investigators by fostering a collaborative research community, accelerate CIP-Net research by removing barriers to accessing analytics expertise, improve the interoperability and usability of CIP- Net data by deploying best practices for data standards and harmonization, and unlock the full potential of CIP- Net activities by sharing data and resources with the broader scientific community. First, we will establish an effective administrative infrastructure and organizational process to coordinate CIP-Net activities, building on our proven and continuously improving systems that currently support the coordination of NCI programs. Second, we will ensure that CIP-Net data are harmonized using standards interoperable with the broader cancer data ecosystem and findable through a centralized virtual repository, leveraging our extensive track record and robust systems for collaborative data sharing and dissemination in consortium studies. Third, we will provide multidisciplinary analytics expertise to support CIP-Net’s collaborative research, drawing on our collective strengths in biostatistics, bioinformatics, and biomedical informatics from Roswell Park’s Department of Biostatistics & Bioinformatics. Fourth, we will actively promote CIP-Net and engage diverse stakeholders to build an inclusive community that leverages a range of perspectives and approaches to address key scientific questions in immunoprevention. Taken together, we envision that our DRCC, in close collaboration with the CIP-Net stakeholders, will enable us to support highly effective and innovative translational studies that address the critical unmet needs in cancer immunoprevention. The main deliverables include: administrative and organizational support to coordinate network activities and facilitate communication and collaboration (Aim 1); policies, workflows, and infrastructure to ensure that all resources generated by CIP-Net are harmonized using standards interoperable with the broader cancer data ecosystem and findable through a centralized virtual repository; multidisciplinary analytics support to accelerate CIP-Net research progress, along with innovative solutions to address CIP-Net’s evolving needs (Aim 2); and community-building and outreach efforts to support immunoprevention research, integrate patient advocates into CIP-Net, and coordinate career development opportunities for early-career scientists (Aim 3).

NCI - National Cancer Institute

Abstract Support is requested for a Keystone Symposia conference entitled “Cancer Immunotherapy: Basic Mechanism Informing Clinical Applications & Combinations” organized by Drs. Jennifer Guerriero, Thomas Marron, Ira Mellman and Solange Peters, with scientific programming input from Keystone Symposia. The meeting will take place at the Fairmont Le Château Frontenac in Quebec City, Quebec, Canada from March 15–19, 2026. While cancer immunotherapy strategies are highly effective, they target only a few immunoregulatory pathways and benefit a limited subset of patients. Most patients either fail to respond or respond briefly before developing resistance. This Keystone Symposia meeting aims to better understand the mechanisms behind this resistance and discuss the immunotherapeutic strategies under development that will harness alternative immune pathways to improve clinical responses. Conference sessions will highlight emerging approaches to targeting stromal and myeloid cells, insights into tumor recognition by lymphoid lineages, and the use of advanced technologies like spatial imaging and AI to understand the tumor microenvironment. Specifically, this meeting will convene leading cancer immunotherapy experts to review the successes and failures of existing therapies, explore new therapeutic targets within host immunity, and discuss the challenges and potential of combination therapies. These interdisciplinary perspectives will provide insight into future clinical applications of novel approaches and optimal combination therapies to advance strategies designed to eliminate cancers through innovative therapeutic approaches using the immune response.

National Institutes of Health

Cancer Prevention and Control Clinical Trials Grant Program (R01 Clinical Trial Required)

National Institutes of Health

Cancer Prevention and Control Clinical Trials Planning Grant Program (R34 Clinical Trials Optional)

National Institutes of Health

Cancer Prevention and Control Clinical Trials Planning Grant Program (U34 Clinical Trials Optional)

National Institutes of Health

Cancer Research Education Grants Program - Courses for Skills Development (R25 Clinical Trial Not Allowed)

National Institutes of Health

Cancer Research Education Grants Program - Curriculum or Methods Development (R25 Clinical Trial Not Allowed)

National Institutes of Health

Cancer Research Education Grants Program - Research Experiences (R25 Clinical Trial Not Allowed)

Cancer Research Foundation

Cancer Research Foundation is an active grantmaking foundation based in Chicago, IL. Focus: health. Contact the foundation directly for current funding opportunities.

Cancer Schmancer Foundation

Cancer Schmancer Foundation is an active grantmaking foundation based in Malibu, CA. Focus: health. Contact the foundation directly for current funding opportunities.

Cancer Support Foundation

Cancer Support Foundation is an active grantmaking foundation based in Fort Smith, AR. Focus: general. Contact the foundation directly for current funding opportunities.