Grants

DEPT OF DEFENSE.DEPT OF THE NAVY.NAVSEA.NAVSEA WARFARE CENTER.NSWC INDIAN HEAD DIVISION

BPA - Translation and Interpreting Service PSC R608

DEPT OF DEFENSE.DEPT OF THE NAVY.NAVSEA.NAVSEA WARFARE CENTER.NSWC INDIAN HEAD DIVISION

BPA-Portable Restroom Rentals

NSF

Technical interviews are a component of hiring for computing positions pervasive in the industry that necessitate solving coding problems in real-time. Apart from obtaining a solution to the task given, job candidates are also encouraged to consider the algorithmic efficiency, to test their approach, and to verbally communicate decisions made throughout. While students are taught programming, algorithms, and data structures during their education, applying these principles under duress can be challenging and often requires immense practice. This BPC Demonstration Project at Florida International University will aid in students’ preparation for these interviews while cultivating professional and technical competencies for Hispanic or Latiné/x/a/o undergraduate students at Hispanic-Serving Institutions (HSIs) in the southeast. Through a combination of research and education, the project will create and disseminate resources that celebrate the diversity of language and cultures of Hispanic or Latiné/x/a/o students using meaningful examples to further understanding of computing concepts. Moreover, this content will provide faculty with lessons and learning activities that they can incorporate throughout curricula and programs to aid in better preparation for a computing career. Ultimately, this initiative will establish opportunities across the participating institutions to empower the next generation of Hispanic or Latiné/x/a/o students in computing. This project seeks to: 1) construct culturally relevant materials for Hispanic or Latiné/x/a/o students, which can be integrated into courses and programs at HSIs in the southeastern region of the U.S.; 2) increase awareness of and familiarity with the technical interview process in academia.; and 3) establish opportunities for students to gain exposure, transfer knowledge, and/or practically apply computing principles needed for career attainment. The project includes a qualitative investigation exploring the conceptions of educators at HSIs in the southeast on the hiring process in computing and how preparation could align with existing institutional structures. Through semi-structured interviews and thematic analysis, approaches that could be effective in enhancing students’ graduate employability will be examined. Alongside an advisory board with combined expertise on our population of focus, academia, and industry, the findings will then be used to develop inclusive content that can be integrated throughout curricula and offered as training by student-led groups. In the following year, the findings will be disseminated through a workshop hosted for faculty and student leaders at HSIs in the southeastern region of the U.S. to share the established resources and collaboratively discuss how these lessons and learning activities could be integrated into existing courses and extracurricular programs.   This award reflects NSF's statutory mission and has been deemed worthy of support through evaluation using the Foundation's intellectual merit and broader impacts review criteria.

NSF

The Historically Black Colleges and Universities Undergraduate Program (HBCU-UP) through the Research on Broadening Participation in STEM funding opportunity provides support for projects that create and advance theory driven models and innovations addressing efforts to promote student success and retention in STEM at HBCUs. This project contributes to increasing national competitiveness and serves the national interest by identifying and scaling effective institutional and departmental practices that promote undergraduate computing majors' academic success and career readiness. HBCUs are essential in promoting the development of the nation's workforce. HBCUs have a long-standing tradition of producing graduates in STEM fields. This project establishes a collaborative network of HBCU computing departments and investigates how institutional and department-level factors influence student persistence and aspirations in computing. Findings contribute to a best practices catalog that informs institutional strategies to enhance computing education. The project also generates critical insights into why some students leave the computing pipeline, providing evidence to strengthen retention efforts and improve the effectiveness of undergraduate STEM education. The study employs a mixed-methods research design guided by theoretical frameworks, such as Astin's Input-Environment-Outcome (IEO) model. Data collection partners in the study are Morehouse College, Spelman College, Clark Atlanta University, Morgan State University, and Winston-Salem State University. The data collection plan includes surveys, departmental document review, and phenomenological semi-structured interviews with undergraduate computing majors, faculty, administrators, and students who withdrew from computing majors. Data are analyzed using a hybrid of deductive and inductive thematic coding to develop institutional models linking student background (input), learning environment (environment), and outcomes (e.g., graduation and career goals). This project goes beyond identifying factors related to success and persistence within computing majors. It is designed to expand understanding of how these factors relate to students' persistence and career aspirations in computing disciplines, which are experiencing exponential growth and require a skilled workforce. The project addresses research questions that investigate key institutional and department-level practices that facilitate the success of computing majors; the ways that these practices promote academic success and influence students' career aspirations within the field of computing; and the undergraduate experiences that contribute to students leaving computing majors at HBCUs. This research project is establishing a collaborative HBCU computing network and producing scalable best practices for computing departments. This award reflects NSF's statutory mission and has been deemed worthy of support through evaluation using the Foundation's intellectual merit and broader impacts review criteria.

NYC Department of Cultural Affairs

Braata Productions

Brackett Foundation

Brackett Foundation is an active grantmaking foundation based in Hamilton, NY. Focus: general. Contact the foundation directly for current funding opportunities.

Bradford Hospital Foundation

Bradford Hospital Foundation is an active grantmaking foundation based in Bradford, PA. Focus: health. Contact the foundation directly for current funding opportunities.

Bradley Hospital Foundation

Bradley Hospital Foundation is an active grantmaking foundation based in Providence, RI. Focus: health. Contact the foundation directly for current funding opportunities.

OD - NIH Office of the Director

PROJECT SUMMARY/ABSTRACT The proposed research facility will provide biomedical research facilities and opportunities for exceptional state-of-the-art pediatric psychiatry research to Bradley Hospital, the nation's first psychiatry hospital exclusively serving children and adolescents. The new Integrative Research Laboratories, located on the campus of Bradley Hospital in East Providence, RI, will create a centralized facility for scientists and their research activities on the hospital campus—steps away from patients who participate in science and who may benefit the most from new discoveries. The proposed facility addresses four core needs: (a) centralizing multiple research groups in a cohesive facility immediately accessible to Bradley's patient populations who participate in research; (b) modernize and expand the capacities of our aging sleep and chronobiology research facility; (c) build a state-of-the-science child and adolescent psychiatry oriented biomarkers and biospecimen assessment and processing laboratory; and (d) create new joint-use assessment spaces that combine the breadth of modern psychiatric research (e.g., observation studies, neurocognitive testing, electrophysiological and psychophysiological recordings, neuromodulation) into a single facility to facilitate dynamic science and new collaborations. We propose construction of a 13,856 square-foot facility that will occupy the second floor of a new building on Bradley's campus (with excess capital costs secured from Hospital and corporate funds). These new Integrative Research Laboratories will include: purpose-built 24- hour-operational environmentally controlled sleep and circadian research suites, sample collection, storage and analysis facilities, assessment rooms focusing on child, family, and group observation and research, centralized performance testing laboratories, 3 purpose-built physiological labs (EEG, psychophysiology and neuromodulation), ample instrumentation storage and freezer space, and dedicated fixed equipment to facilitate research success. Together, this new facility will transform the research capacities of Bradley Hospital, solving multiple long-standing challenges to our scientific endeavors. Research accomplished in these laboratories will benefit the children and families in RI, greater New England, and across the nation by enhancing knowledge and understanding of pediatric mental health. Our construction and design plan meets the highest standards of modern facilities to ensure the long-term utility of this space. We note that the hospital and corporate institution (Brown University Health) have pledged approximately $13.7 million to ensure the viability of this biomedical research facility. Our new Integrative Research Laboratories facility will provide the infrastructure to support Bradley Hospital as a national and international leader in child and adolescent psychiatry research well into the 21st century.

NIMH - National Institute of Mental Health

The goal of my F31 Predoctoral Fellowship application is to receive integrated multidisciplinary training in cellular and molecular neurobiology and immunology toward establishing my future independent research career at the critical intersection of neurodevelopmental disorders and aging. Neurodevelopmental disorders are most commonly studied in childhood and adolescence, however the challenges associated with aging for the nearly 6 million adults in the United States currently living with autism spectrum disorder (ASD) remain largely unexplored. Decades of research reveal that the brains of children with ASD undergo an altered growth trajectory characterized by excess brain volume, neuron density, and connectivity. Although comparatively little is known about the course of brain development throughout adulthood in ASD, alterations are characterized by cell, spine, and myelin loss –signaling an increased risk of developing age-related cognitive impairments. Chronic neuroimmune activation in ASD throughout development provides a plausible mechanism for increased vulnerability to age-related processes. My dissertation explores part of an overarching framework that early excess brain growth, local hyper-connectivity, and imbalanced neuronal signaling triggers a cycle of neuroinflammatory responses and cell damage contributing to neuropathogenic processes into adulthood. With my outstanding mentorship team, I propose to characterize age-related changes in neuroimmune profiles (Aim 1), immune cell phenotypes (Aim 2), and neuronal inflammation (Aim 3) throughout adulthood. I will use postmortem human brain tissue from individuals with ASD and unaffected controls 20-70 years of age and target regions related to core socioemotional deficits, the amygdala and superior temporal gyrus (STG), and the hippocampal formation, a region principally implicated in aging. I have unique access to an extensive collection of clinically and genetically well characterized postmortem human brains through our tissue collection program. Through my dissertation research, I will receive training in novel, cutting edge methods on human tissue including single molecule fluorescence in situ hybridization (smFISH) HiPlex RNAscope to spatially map within-cell transcriptomic profiles. With these findings, we can begin to identify cellular and molecular phenotypes most vulnerable to pathological aging and windows for intervention to promote healthy aging in the rapidly growing population of autistic adults.

NIMH - National Institute of Mental Health

PROJECT SUMMARY Pathophysiological studies in first episode psychosis (FEP) have been inconsistent due to the heterogeneity in age of onset, clinical presentation, and neurobiology in schizophrenia spectrum disorders (SSD). Neuroimaging studies, postmortem investigations, and blood-based biomarker experiments provide intriguing insights into potential abnormalities related to the barriers of the brain of individuals with SSD, but only 1% of existing studies have focused on mid- to late-life FEP. Clinical and biomarker studies in SSD have repeatedly shown three phenomena: First, is blood brain barrier (BBB) dysfunction in neuroimaging, postmortem, blood- and CSF-based studies in individuals with SSD. Second, is the involvement of the blood cerebral spinal fluid barrier (BCSFB) as evidenced by enlargement of the choroid plexus (ChP) in SSD, FEP and in individuals at high risk for psychosis. Third, there is a nascent but growing research area related to the disruption of the glymphatic system (GS) in SSD. Moreover, there is a growing body of evidence in aging, sleep, and neurodegenerative studies suggesting a link between disruptions in the BBB, BCSFB, and GS to clinical outcomes. These barrier systems, regulate trafficking between the blood and the brain through physical, enzymatic, transport, and immunological processes, and they have tightly regulated interrelationships between them to ensure a healthy brain environment. However, despite the complementary roles between the BBB, BCSFB, and GS, the interaction between these systems in mid- to late-life FEP has not been explored. Advances in neuromaging and blood-based techniques have improved upon existing tools to assess BBB, BCSFB, and GS function and they include gadolinium-enhanced MRI methods like dynamic contrast enhanced-MRI (DCE-MRI) and the isolation of circulating brain microvascular endothelial cells (cBMECs) in the blood. Therefore, the critical need and overall objectives for this study are to unite neuroimaging, cBMEC, and clinical phenotypes in the same individuals to mechanistically link barrier disruptions to clinical outcomes in mid- to late-life FEP. Our central hypothesis is that biomarkers of BBB, BSCFB, and GS dysfunction are associated with poorer clinical outcomes in mid- to late-life FEP. Here, we aim to test the hypothesis that: 1) barrier/GS disruptions are associated with mid- to late-life FEP, 2) cBMECs are a proxy of BBB deficits in mid- to late-life FEP, and 3) barrier/GS deficits are associated with worse symptoms, cognition, and functioning in mid- to late-life FEP. Lastly, we will determine the interrelationship between barrier and GS deficits in mid- to late-life FEP. The proposed research is innovative in combining in vivo imaging of the BBB, BCSFB, and GS with clinical measures in the same individuals to better understand the barrier/GS deficits associated with clinical outcomes in mid- to late-life FEP. The proposed research is significant because it will lay the groundwork for a robust non-invasive platform to screen for cBMECs to pathophysiologically stratify patients, a first for SSD, that may lead to the prioritization of novel therapeutic approaches to regulate barrier dysfunction in SSD.

Brain Canada Foundation

Brain Canada catalyzes brain research through the Canada Brain Research Fund, supporting projects on neurological and mental health conditions.

NIMH - National Institute of Mental Health

To take advantage of recent and ongoing advances in intensive and large-scale computational methods and to preserve the scientific data created by publicly funded research projects, archives for sharing data must be created, as well as standards for specifying, identifying, and annotating deposited data. The value of an interest in such archives among researchers can be greatly increased by adding to them an active computational capability and framework of analysis and search tools that support further analysis as well as larger-scale meta-analysis and large-scale data mining. OpenNeuro.org, founded as a repository for functional magnetic resonance imaging (fMRI) data, is such an archive. We have built a web portal, NEMAR, to OpenNeuro data for human electrophysiology data (EEG and MEG) and for intracranial (iEEG) data recorded from clinical patients during planning for brain surgery or other therapies – we here refer to these as neuroelectromagnetic (NEM) data. NEMAR, maintained at the San Diego Supercomputer Center, acts as a portal to NEM data shared publicly via the OpenNeuro data archive. Upon receipt by OpenNeuro, NEM data are copied to NEMAR and made available for processing without charge on the ACCESS high-performance computing resources of the San Diego Supercomputer Center (SDSC) via the Neuroscience Gateway (NSG) project. NEMAR offers a search engine for NEM data whose results can be inspected in detail from a web browser, including visualizations of data from each subject plus a number of data activity measures and quality estimates. A forum for each dataset records visitors’ comments and lists papers citing the data. Next, we will build large, multimodal foundational deep neural network models allowing users to explore relationships between NEM signal brain dynamics, experience, and behavior.

National Institutes of Health

BRAIN Initiative: Next-Generation Devices for Recording and Modulation in the Human Central Nervous System (UG3/UH3 Clinical Trial Optional)

National Institutes of Health

BRAIN Initiative: Brain Behavior Quantification and Synchronization- Next Generation Sensor Technology Development (U01 Clinical Trial Optional)

National Institutes of Health

BRAIN Initiative: Clinical Studies to Advance Next-Generation Devices for Recording and Modulation in the Human Central Nervous System (UH3 Clinical Trial Optional)

National Institutes of Health

BRAIN Initiative: Data Archives for the BRAIN Initiative (R24 Clinical Trial Optional)

National Institutes of Health

BRAIN Initiative: Development and Validation of Novel Tools to Probe Cell-Specific and Circuit-Specific Processes in the Brain (R01 Clinical Trial Not Allowed)

National Institutes of Health

BRAIN Initiative: New Concepts and Early-Stage Research for Recording and Modulation in the Nervous System (R21) (Clinical Trial Not Allowed)

National Institutes of Health

BRAIN Initiative: New Technologies and Novel Approaches for Recording and Modulation in the Nervous System (R01 Clinical Trial Not Allowed)

National Institutes of Health

BRAIN Initiative: Optimization of Instrumentation and Device Technologies for Recording and Modulation in the Nervous System (U01 Clinical Trials Not Allowed)

National Institutes of Health

BRAIN Initiative: Preclinical Proof of Concept for Novel Recording and Modulation Technologies in the Human CNS (R18 - Clinical Trial Not Allowed)

National Institutes of Health

BRAIN Initiative: Production and distribution facilities for brain cell type-specific access reagents (U24 Clinical Trial Not Allowed)

National Institutes of Health

BRAIN Initiative: Promoting Health for All Through BRAIN Technology Partnerships (R34 - Clinical Trials Not Allowed)