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120kV Transmission Electron Microscope

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OD - NIH Office of the Director

Twenty-four NIH-funded investigators studying a wide range of biomedical research topics at the University of Maryland Baltimore (UMB) are requesting funds for a transmission electron microscope (TEM), the Talos L120C G2 (Thermo Fisher Scientific). UMB has a long history of TEM use conducted at the Electron Microscopy Core Imaging Facility (EMCIF), and the decommissioning of the current TEM has drastically impeded the ongoing research projects. This TEM will replace an 20-year-old Thermo Tecnai T12, a 120 kV tungsten filament instrument, whose reliability and stability were decreasing when we lost the capability to capture images. Through demonstrations of microscopes from several vendors as well as Director and user experiences, the Thermo Talos L120C G2 is the ideal replacement research microscope with its high-contrast, high-resolution optics for biological samples. Its lanthanum hexaboride crystal electron source and Ceta 16M CMOS and Smart digital camera will produce bright, well-contrasted images for all our users. Its user-friendly software interface with features such as motorized stage, alignment recall, automated apertures, and rapid specimen exchange make this a good fit for a core facility. The remote operation features are ideal for training users and providing fee-for-service to distant users. The Talos L120C will be placed in the current TEM room, which is a pre-existing, well-designed space with convenient access to the main Core lab and staff. It will be administered by the EMCIF which is part of the Center for Innovative Biomedical Resources (CIBR) which provides resources to UMB researchers. Our staff will provide training in sample preparation and in operation of the new TEM. EMCIF is jointly supported by the School of Dentistry and the School of Medicine. We support research across the entire UMB campus as well as the University of Maryland System. The new TEM will be placed into the existing recharge system available to users through an iLab software interface available through the web and as a smart phone app. The new TEM will support continued progress of NIH-funded research projects of UMB scientists that are relevant to our mission of improving the human condition and serve the public good of Maryland. The EMCIF has a strong record of collaboration with researchers providing electron microscopy results for presentations, publications and grant applications. Strong institutional support provides for Director and staff salaries, space, instrument service/maintenance, administrative services and other EMCIF operating costs. If funded, the Talos L120C will be the primary TEM for UMB faculty research, and it will expand our capacity for biomedical research at UMB and at regional institutions. The impact will extend beyond the cancer, blood, infectious disease, bone development and other research projects listed in this proposal. The EMCIF’s mission is to provide state-of-the-art instrumentation and training to researchers, trainees, graduate students and staff. We aim to train the next generation of scientists to appreciate and interpret electron micrographs.

Up to $674K
2027-05-14
health research

Free to search & build · $99 one-time to unlock the application pack · No subscription

2026 Environmental Sciences: Water Gordon Research Conference and Gordon Research Seminar

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NIEHS - National Institute of Environmental Health Sciences

The Gordon Research Conference on Environmental Sciences: Water is to be held June 14-19, 2026, in Holderness, NH. The 2026 conference theme is Novel Approaches and Tools to Address Aquatic Impacts on Human and Environmental Health and will feature a program of thought-provoking research by leading researchers and experts in the field of water quality science and technology. The conference will bring together 190 participants from multiple countries in an immersive and informal setting. The program will feature a series of plenary talks by established and emerging researchers, as well as daily poster sessions by conference attendees. The overarching theme of the 2026 conference recognizes that state-of-the-art research is needed to understand challenges facing water resources, and to develop solutions to address these challenges. Ensuring water quality is critical for protecting human and ecosystem health, as well as maintaining ecosystem services. This conference will showcase innovative researchers who focus on current water resources challenges, including the presence of persistent contaminants and pathogens, access to clean water for communities, and environmental stresses on water. This aspect of the conference will provide a forum for discussing and evaluating the most pressing water issues of our time. The conference will highlight scientists who directly study environmental impacts through field measurements and community engagement, along with those working at the science-policy interface. Specific aims of the conference are to: 1) Feature a scientific program that links water quality issues, the protection of human health, and sustainability of environmental resources through a plenary program of leading researchers from different fields and perspectives - themes include chemical and biological exposures, human health impacts, and innovative solutions for the management of water resources; 2) Advance discovery while promoting mentoring, networking and learning by offering a platform for graduate student and postdoctoral researchers to present their research at the full conference, as well as provide a venue for informal interactions between senior scientists and trainees and broad participation of scientists from different professional settings; and 3) Provide a conference that fosters discussion and debate of research results through close interaction of participants from academia, industry, and government laboratories. Funds will be used to support the attendance of invited plenary speakers, as well as graduate students and postdoctoral trainees. Outcomes related to the quality of the scientific program, discussion, management, and atmosphere will be evaluated through surveys of conference attendees. 1

Up to $18K
2026-12-31
health research

Free to search & build · $99 one-time to unlock the application pack · No subscription

2026 Lipoprotein Metabolism Gordon Research Conference and Gordon Research Seminar

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NIDDK - National Institute of Diabetes and Digestive and Kidney Diseases

ABSTRACT Abnormal lipid and lipoprotein metabolism is mechanistically linked to many common diseases such as obesity, fatty liver, diabetes, cardiovascular disease (CVD), and neurodegenerative diseases. The Gordon Research Conference (GRC) on Lipoprotein Metabolism is recognized as a premier meeting for disseminating cutting-edge research, sparking collaborations, and fostering new paradigms in this fast-moving field. The 2026 GRC will continue this tradition of highlighting research excellence in various areas of lipid and lipoprotein metabolism. The conference, to be held in Waterville Valley, NH from June 2-7, will focus on important new developments in lipid and lipoprotein metabolism relevant to human disease. Oral presentations (in 9 integrated sessions) will highlight state-of-the-art scientific approaches, exploring molecular, structural and cell biological studies, model systems of metabolism, and preclinical and human studies of new therapeutic targets. The overarching goal is to bring together scientists from diverse research areas, career stages, and geographical locations who share a passion for discovering and applying new paradigms in lipid and lipoprotein metabolism to improve human health. The GRC will be preceded by the Gordon Research Seminar (GRS), a forum for trainees to present their research in a setting of mentorship and inspiration provided by peers and selected faculty in attendance. The First Aim of the 2026 GRC on Lipoprotein Metabolism is the communication of cutting-edge, unpublished science on lipoprotein metabolism. This includes 45 presentations in 9 oral sessions, each with an identified theme and a discussion leader who will facilitate dialogue and encourage participation by all attendees. Several of the oral sessions will feature short presentations by trainees and early career investigators, selected from submitted abstracts by a panel of established investigators. The roster of confirmed speakers is an impressive array of leading researchers from a range of career stages and represent the world’s best scientists in the area of lipid and lipoprotein metabolism. Our Second Aim is to achieve broad participation and engagement opportunities for all attendees. GRCs place high priority on the principles of safety and the creation of a welcoming environment. The 2026 GRC on Lipoprotein Metabolism has long-standing reputation as a safe and engaging meeting for all participants to share their unpublished results in a collegial manner. We expect this meeting to discuss the opportunities and challenges for emerging therapies for diseases such as CVD, obesity, diabetes, fatty liver disease, and Alzheimer’s and related dementias. Collectively, we expect the 2026 Gordon Research Conference (GRC) on Lipoprotein Metabolism to improve human health through promoting open dialogue, collaboration, and scientific innovation.

Up to $25K
2027-05-31
health research

Free to search & build · $99 one-time to unlock the application pack · No subscription

2026 Lymphatics Gordon Research Conference and Seminar

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NHLBI - National Heart Lung and Blood Institute

PROJECT SUMMARY The objectives of the 2026 GRC “Lymphatics” are to present state-of-the-art research on the lymphatic vascular system, to fuel scientific exchange across scientific disciplines and expertise, and to spearhead new ideas and collaborations. The meeting will bring together investigators from all backgrounds and from all career stages, converging on lymphatics as one common theme. Specific Aims are (1) To present conceptual advances in research of the lymphatic vascular system and its pathologies; (2) To discuss paradigm shifting findings of lymphatics in different organ systems and their contribution to disease; (3) To integrate knowledge from different disciplines; and (4) To nurture junior investigators and trainees entering the lymphatic research field. Sessions will cover conceptual advances in development and disease of lymphatic vessels from basic aspects to potential clinical applications. The meeting will highlight recent insights into the diversity and organ-specificity of lymphatic endothelium. Novel molecular regulators for lymphatic vasculature during bone development, Schlemm’s canal in the eye and lacteals in the intestine will be discussed. New factors regulating lymphangiogenesis and lymphatic integrity will be introduced. Advances in research on lymphatic malformations, lymphedema and other congenital lymphatic diseases will be discussed. The meeting will also present emerging concepts on the role of lymphatics in atherosclerosis, myocardial infarction, and congestive heart failure. Paradigm shifts in the field will be presented, and crosstalk between lymphatics and immune system discussed. Advances in understanding how lymphatics contribute to disease, including cardiovascular inflammation, cancer, autoimmune and neurodegenerative diseases will be highlighted. A key goal for this meeting is to serve as a platform for growth of lymphatic research, and for helping to promote new scientists entering this research field. Abundant opportunities for the presentation of research by early career investigators will be provided. The GRS on Lymphatics organized by junior investigators will provide opportunities exclusively for junior investigators to present their work and form collaborations. Aside from presentation and poster sessions, a career development session will also be held during GRS to provide guidance to those just getting their start in the lymphatic research field, and to discuss strategies for how to navigate issues impeding lymphatic research or obstacles to participation by incoming lymphatic researchers. A patient session will also be held to allow researchers to hear from those suffering from lymphatic diseases and hear their perspective on the potential promise of translating lymphatic research into new therapies. The sponsoring organization is dedicated to advancing the frontiers of science. In accordance with its mission, this conference will place emphasis on the presentation of unpublished data, high-quality science and rich discussions in many fields, such as cardiovascular disease, cancer, immunology, metabolism and neurobiology. We anticipate that the opportunities provided to young investigators participating in this conference will facilitate their rise as future leaders of the lymphatic research field.

Up to $5K
2027-01-31
health research

Free to search & build · $99 one-time to unlock the application pack · No subscription

2026 Lysosomes and Endocytosis Gordon Research Conference and Gordon Research Seminar

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NIA - National Institute on Aging

Project Summary NIH supported research aims to advance our understanding of biological systems, improve the control of disease, and enhance health. It is well-recognized that connecting investigators with complementary expertise’s in fundamental cell biology, biochemistry, genetics, state of the art imaging with those developing avenues for the treatment of disease are essential to get effective advances. This grant proposal seeks support for the 2026 Gordon Research Conference (GRC) and associated Gordon Research Seminar (GRS) on Lysosomes and Endocytosis, with a central theme of “Endosomes and Lysosomes in Action Across Cells, Tissues and Disease States”. As the field of Lysosomes and endocytosis evolves with increasing research in this aging related topics, the 2026 meeting will place an important emphasis on neurodegenerative disease, specifically Alzheimer Disease and related aging disorders. Exploring at the cellular, molecular and structural levels how defects in lysosomal and endocytic processes contribute to disease onset and progression are essential fundaments for therapeutical intervention. Endosomes and lysosomes are critical components of the endomembrane system, orchestrating essential cellular processes including cargo sorting, degradation, membrane trafficking, and signaling. Their coordinated activity ensures proper cellular homeostasis and adaptability across a wide range of cell types and tissue environments. Emerging evidence highlights their dynamic and context-dependent roles in development, immunity, metabolism, and cell fate determination. Notably, dysregulation of endo-lysosomal pathways is increasingly recognized as a central contributor to the pathogenesis of numerous diseases, including neurodegenerative disorders, cancers, metabolic syndromes, and lysosomal storage diseases. The GRC will bring together internationally recognized experts and emerging scientists to present unpublished data, stimulate discussion, and develop new collaborations. The GRS, held prior to the main conference, will offer a focused environment for trainees and junior researchers to present their work and build professional networks to boost their careers.

Up to $40K
2027-05-31
health research

Free to search & build · $99 one-time to unlock the application pack · No subscription

2026 Membrane Transport Proteins Gordon Research Conference and Gordon Research Seminar

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NIDA - National Institute on Drug Abuse

PROJECT SUMMARY The 2026 Gordon Research Conference on Membrane Transport Proteins, “The Dynamic Membrane Transporter: Gateways to Health & Disease,” will convene ~200 investigators from academia, industry, and medicine at the Renaissance Tuscany Il Ciocco, June 14–19 (trainee-led GRS, June 13–14). This location facilitates participation by a broad international community of scientist, trainees, and early-career scientists working on membrane transport proteins. The broader scientific exchange directly benefits public health in the United States by speeding advances in the understanding of disease mechanisms, the development of new drugs, and the identification of promising therapeutic strategies. It also ensures that the United States researchers remain fully engaged with the discoveries, technologies, and research shaping drug discovery in this important field. Membrane transporters comprise roughly 10 % of the human genome, yet fewer than 4 % are clinically exploited, despite their central roles in prevalent disorders, including autism, depression, ADHD, addiction, and diabetes, and in rare diseases such as Christianson syndrome and mucoviscidosis. Breakthroughs in cryo-EM, AI-driven structure prediction, live-cell biosensors, and human-derived disease models now make it possible to translate fundamental transporter biology into first-in-class therapeutics, creating a timely need for a forum that seamlessly links molecular mechanisms to clinical applications. The program’s nine themed sessions and two plenary lectures deliberately pair structural and mechanistic discoveries with preclinical and clinical perspectives, covering topics from vesicular neurotransmitter loading and blood–brain-barrier gateways to ABC/OCT1-mediated drug disposition. Interwoven “Technology Spotlight” talks and “Reality-Check” panels will showcase state-of-the-art methods while candidly addressing their limitations, establishing rigorous, field-wide standards. A 1.5-day, trainee-run Gordon Research Seminar, anchored by keynote mentors Drs. Sara Jones and Walter Boron, plus mentoring innovations such as “Scientist Speed-Dating” lunches and the forum Breaking the Mold: Overcoming Barriers to Career Advancement will foster an inclusive, supportive environment that cultivates the next generation of transporter scientists. Guided by three specific aims, catalyzing translational science, elevating rigor and reproducibility, and building a global workforce, the conference is poised to reveal new transporter ligands, biomarkers, and drug-delivery strategies; to disseminate best-practice methodologies; and to launch enduring mentorship networks. By uniting siloed disciplines in a confidential, off-the-record environment that encourages presentation of unpublished data, the 2026 GRC will accelerate transporter-based solutions for some of today’s most urgent unmet medical needs.

Up to $39K
2027-05-20
health research

Free to search & build · $99 one-time to unlock the application pack · No subscription

2026 Neural Development Gordon Research Conference and Seminar

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NICHD - Eunice Kennedy Shriver National Institute of Child Health and Human Development

Project Summary The Neural Development Gordon Research Conference (GRC) is a premier, international scientific conference focused on advancing the frontiers of science through the presentation of cutting-edge and unpublished re- search, prioritizing time for discussion after each talk and fostering informal interactions among scientists of all career stages. The conference program includes a broad range of speakers and discussion leaders from insti- tutions and organizations worldwide, concentrating on the latest developments in the field. The conference is five days long and held in a remote location to increase the sense of camaraderie and create scientific commu- nities. In addition to premier talks, the conference has designated time for poster sessions and afternoon free The 2026 GRC on Neural Development at Salve Regina University in Newport, Rhode Island USA will bring together scientists who investigate fundamental questions related to nervous system development, using molecular, cellular and organismal approaches. Topics include the genesis of neurons and glia, cell lineages, cell-cell communication including with CNS-resident immune, vascular and fibroblasts, and the assembly of neural circuitry. time, and communal meals allow for informal networking opportunities with leaders in the field. Our excep- tional speakers will address cutting-edge questions including how evolution shaped the emergence and diversi- fication of extant nervous systems, how developmental mechanisms prime the nervous system for future function In line with these broad topics, speakers employ a range of classical and emerging model organisms including flies, frog, fish, mice, ferrets, and non-human primates. They also use state-of-the art human-cell based models like neural organoids. The invited speakers employ broad approaches including: molecular genetic techniques and genomic approaches such as transcriptomic and epigenetic profiling; single cell mRNA sequencing and lineage barcoding; CRISPR-based manipulations and screens; live-imaging and high-resolution microscopy; neuroimaging and human genetics. The meeting will promote extensive exchanges between junior and senior scientists from different career stages, geographic locations and scientific interests. This collegial atmosphere will be fostered through interactions at talks, poster sessions, meals, and informal gatherings during free time. Networking will be promoted with journal editors and members of funding agencies that support research in this field. There will also be many short talks selected from abstracts, which will feature the most exciting recent work by early-career researchers We en- courage applications from researchers across institutions, career stages, countries, and relevant scientific topics, with the goal of having broad participants to enrich the meeting. A GRS is reserved for trainees only, including PhD students and postdocs. This will precede the meeting, and is organized and run by trainees, and will include sessions on related topics along with an invited keynote speaker. and how the nervous system ages under healthy and pathological conditions. .

Up to $20K
2027-04-30
health research

Free to search & build · $99 one-time to unlock the application pack · No subscription

2026 Proteoglycans Gordon Research Conference and Seminar

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NIAMS - National Institute of Arthritis and Musculoskeletal and Skin Diseases

Since 1984, the biennial Proteoglycans (PGs) Gordon Research Conference (GRC) has been an essential meeting for PG researchers. Recognized as the leading international forum for PG and glycosaminoglycan (GAG) research it brings together established and new PG researchers in a collegial and scientifically stimulating environment. Important to the meetings success is a history of a collegial atmosphere that fosters the dissemination of unpublished and emerging research that stimulates scientific discussions and collaborations among all attendees. This proposal is requesting partial support for the next PGs GRC, “Frontiers in Basic and Translational Proteoglycan Research to Improve Human Health,” which will be held from June 28th to July 3rd, 2026, and the associated PG GRS entitled, “Integrated Proteoglycan Research to Improve Human Health,” to be held on June 27th - 28th, 2026 at Proctor Academy, Andover, NH. An Executive Committee consisting of former Chairs of PGs GRCs plus organizers of meetings for the international conferences on PGs (ICP) and the International Society for Hyaluronan Sciences (ISHAS) offers input on the conference program. An advisory committee, consisting of expertise in various subfields in proteoglycan research, has been formed. Both committees provide expertise across a broad area, including fundamental, translational, and clinical PG research. The meeting will bring together highly regarded scientists performing impactful PG research and developing new techniques to support proteoglycan research advancement, some of whom will be attending this meeting for the first time. The invited scientists will present the latest findings in fundamental PG research addressing biosynthesis, catabolism, and technological advances in the field. A major focus of this GRC will be highlighting PGs as therapeutic tools and targets. To provide early-stage investigators an opportunity to highlight their research, the meeting program includes short talks during oral session and poster sessions each day. Short talks will be selected from abstracts to be complementary to the theme of the associated oral session. The scientific program aims to present state-of-the-art science to spark scientific discussions and collaborations, leading to the generation of new ideas, innovative research projects, and new grant proposals. The organizers have and will continue to pay careful attention to the participation from different stages in the scientific careers in all aspects of the conference. In the meeting, Dr. Kaori Oshima (MGH), Dr. Rob Ritcher (University of Alabama at Birmingham) and Dr. Paul DeAngelis (University of Oklahoma) will serve as panelists to talk about their experience in overcoming the challenges in academia and discussing different career opportunities for young graduate students and trainees. Attendees of this meeting will be selected by invitation or from the applications submitted online with careful attention. We expect approximately 200 attendees to this conference.

Up to $34K
2027-04-14
health research

Free to search & build · $99 one-time to unlock the application pack · No subscription

2026 Sleep Regulation and Function Gordon Research Conference and Gordon Research Seminar

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NINDS - National Institute of Neurological Disorders and Stroke

SUMMARY: The 2026 Gordon Research Conference (GRC) on Sleep Regulation and Function, themed “Sleep for the Whole Organism,” will mark the seventh installment of this highly successful series. Over the course of the last decade, sleep research has experienced remarkable growth across a variety of disciplines, spanning molecular biology, systems neuroscience, and mental health. Advances in state-of-the-art technologies have enabled significant progress in our understanding of the neurocircuitry underlying non-REM and REM sleep, wakefulness, the roles of neurotransmitters and neuromodulators, genetic contributions to sleep regulation, and the impact of sleep loss on transcriptional and translational dynamics. The 2026 GRC will build on this strong foundation while expanding into new frontiers. The program will explore sleep as a whole-organism behavior, integrating both brain and body perspectives. In addition to core sessions on sleep regulatory mechanisms and emerging findings from non- mammalian species, the conference will highlight recent findings on sleep’s roles in cognition, consciousness, interoception, and waste clearance from the brain. A session will examine the interplay between sleep and post- infectious disease states, reflecting growing interest in how immune challenges—including long-term consequences of viral infections—impact sleep regulation and homeostasis. The program will further emphasize bidirectional brain-body communication, with discussions on the bi-directional interaction between sleep and peripheral physiology, metabolic state, and systemic signals. Finally, the growing interface between artificial intelligence/machine learning (AI/ML) and sleep science will be showcased, illustrating how advanced computational tools are transforming data analysis, predictive modeling, and mechanistic discovery in the field. This GRC will comprise 50 invited speakers and discussion leaders, poster sessions, in the main meeting. It will be preceded by the GRS, which will provide opportunities specifically for graduate students and post-docs. The GRC and GRS will bring together scientists of all career stages in an interactive and safe environment.

Up to $20K
2027-03-31
health research

Free to search & build · $99 one-time to unlock the application pack · No subscription

30-Day Notice for the “Creative Forces®: NEA Military Healing Arts Network Community Arts Engagement Subgranting Program Evaluation Forms” Proposed Collection; Comment Request

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National Foundation on the Arts and the Humanities

The National Endowment for the Arts (NEA), as part of its continuing effort to reduce paperwork and respondent burden, conducts a preclearance consultation program to provide the general public and Federal agencies with an opportunity to comment on proposed and/or continuing collections of information in accordance with the Paperwork Reduction Act of 1995. This program helps to ensure that requested data can be provided in the desired format; reporting burden (time and financial resources) is minimized; collection instruments are clearly understood; and the impact of collection requirements on respondents can be properly assessed. Currently, the National Endowment for the Arts is soliciting comments concerning the proposed information collection through a mixed-methods evaluation of the Creative Forces[supreg]: NEA Military Healing Arts Network Community Arts Engagement Grant Program. The evaluation uses primary and secondary data, and includes interviews, case study site visits, a Participant Survey for individuals who participate in community arts programs, and an Arts Engagement Facilitator Survey for those leading the arts activities. Copies of this ICR, with applicable supporting documentation, may be obtained by visiting www.Reginfo.gov.

See notice
Arts & Culture

Free to search & build · $99 one-time to unlock the application pack · No subscription

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