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Improving Outcomes of Adolescents in Residential Substance use Treatment via a Technology-Assisted Parenting Intervention

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NIDA - National Institute on Drug Abuse

Project Description When parents engage in their adolescents' substance use (SU) treatment, the adolescents experience better outcomes and lower risk of relapse. Yet, parent engagement remains low across the SU treatment continuum, particularly in service lines designed for adolescents with severe SU. To address this gap, we created Parent SMART – a scalable technology-assisted intervention (parent networking forum + online program + telehealth coaching sessions) – to engage parents in adolescent residential SU treatment. Through a successful NIDA- funded R34 and the first segment of this R37, we established Parent SMART's feasibility, acceptability, and preliminary effectiveness on parenting processes, adolescent SU, and adolescent school-related problems. We also showed our ability to conduct a pragmatic effectiveness trial and efficiently integrate Parent SMART into two of the largest adolescent residential facilities in the country: Rosecrance Griffin Williamson and Hazelden Betty Ford. With the enthusiastic support of our partners, we now propose to adapt Parent SMART to reflect a changing national treatment landscape. Since 2010, the numbers of residential programs for youth with SU and other behavioral health problems, youth served, and available beds have declined by 61%, 78%, and 66%, respectively, while the use of crisis hotlines, outpatient wraparound services, and intensive outpatient services has surged. This shifting service mix highlights the need to proactively enhance parent engagement across the SU continuum of care. In this next R37 segment, we will adapt and implement Parent SMART to ensure that it fits the needs of parents, adolescents, and staff in those service lines experiencing a surge in utilization. Parent SMART adaptation will be guided by ADAPT-ITT, an 8-step, systematic process to adapt evidence-based interventions. In the first six steps of ADAPT-ITT, we will identify core intervention elements that transcend settings and solicit constituent feedback to adapt modifiable, peripheral elements (Aim 1). In the final two steps of ADAPT-ITT, we will employ a hybrid type 2 effectiveness-implementation trial to simultaneously evaluate the adapted Parent SMART intervention and its implementation (Aim 2). Parent SMART implementation will be guided by the Science-to-Service Laboratory, a three-tiered (didactic workshop + performance feedback + coaching) strategy that has demonstrated effectiveness across several of PI Becker's clinical trials. To harmonize data collection across R37 segments, we will use the same measures of patient effectiveness (parental monitoring, parent-adolescent communication, adolescent SU) and assessment calendar (baseline, 12-, and 24-weeks). Implementation outcomes will include reach, adoption, and fidelity, following guidelines of the NIDA-funded Research Adoption Support Center, to align with other research networks. This work will advance the field by: targeting a high-need population wherever they access services; removing barriers to parent engagement; testing the adapted intervention and its implementation simultaneously to accelerate impact; and informing development of a Parent SMART commercialization and sustainment plan. D UEI: KG76WYENL5K1 Enter name of Organization: D RESEARCH & RELATED BUDGET - Budget Period 1 OMB Number: 4040-0001 Expiration Date: 11/30/2025 Northwestern University Budget Type: Project ? Subaward/Consortium Budget Period: 1 Start Date: 06/01/2026 End Date: 05/31/2027 A. Senior/Key Person Months Requested Fringe Funds Prefix First Middle Last Suffix Base Salary ($) Cal. Acad. Sum. Salary ($) Benefits ($) Requested ($) Sara Becker 221,900.00 2.40 44,380.00 12,471.00 56,851.00 Project Role: PD/PI D D Sarah Helseth 148,447.00 3.00 37,112.00 10,428.00 47,540.00 Project Role: Co-Investigator D Zabin Patel 109,273.00 1.20 10,927.00 3,071.00 13,998.00 Project Role: Co-Investigator Additional Senior Key Persons:Add Attachment Delete Attachment View AttachmentTotal Funds requested for all Senior Key Persons in the attached file Total Senior/Key Person 118,389.00 B. Other Personnel Number of Personnel Project Role Post Doctoral Associates Graduate Students Undergraduate Students Secretarial/Clerical n n n n 2 1 n Research Assistants Project Manager 3 Total Number Other Personnel Months Requested Fringe Funds Cal. Acad. Sum. Salary ($) Benefits ($) Requested ($) D D D D 24.00 D 6.00 D D D D D D D D D D 99,000.00 39,784.00 27,820.00 11,179.00 126,820.00 50,963.00 Total Other Personnel Total Salary, Wages and Fringe Benefits (A+B) n 177,783.00 296,172.00 n

Up to $804K
2031-04-30
health research

Free to search & build · $99 one-time to unlock the application pack · No subscription

Integrating Behavioral Pain Management to Improve Physical Activity in Family-based Behavioral Treatment for Pediatric Obesity

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NIDDK - National Institute of Diabetes and Digestive and Kidney Diseases

PROJECT SUMMARY/ABSTRACT Chronic pain is prevalent in youth with obesity and confers risk for declining physical function and quality of life. Left unaddressed, chronic pain often persists into adulthood and is associated with staggering costs to individuals and to society. Despite evidence that chronic pain attenuates responsiveness to weight management intervention, there is a lack of safe and effective behavioral interventions for pain management in pediatric patients with obesity. The long-term objective of this work is to improve obesity treatment outcomes by optimizing strategies to decrease pain and improve physical activity in youth with co-occurring obesity and chronic pain (CPO). Guided by the ORBIT Model of Behavioral Intervention Development, the goal of this proposal is to develop, refine, and pilot test an adjunctive behavioral pain management intervention that targets physical activity in youth with CPO who are participating in family-based behavioral treatment (FBBT) for pediatric obesity (i.e., IMPACT-FBBT). In Aim 1, the PI and his mentorship team will identify biological, psychological, and social factors that are predictive of moderate-to-vigorous physical activity (MVPA) and sedentary behavior in youth with CPO (N=20). In Aim 2a, these data will be used to inform the initial development of the IMPACT-FBBT intervention, which will be based on a highly successful behavioral treatment program that has been implemented in youth with chronic widespread pain (i.e., FIT Teens) but modified with input from youth with CPO and their families (n=10) and multidisciplinary experts who treat youth with CPO (n=5). Then, in Aim 2b, the investigative team will refine IMPACT-FBBT through sequential testing with youth with CPO (n=6 minimum) and structured participant feedback. Intervention refinement will continue until we achieve feasibility and acceptability ratings that exceed >80% or until N=12 youth with CPO complete the intervention and provide feedback. In Aim 3, we will pilot test the refined IMPACT-FBBT intervention with N=30 adolescents with CPO and assess recruitment, retention, and dose received. This information will be used to inform the future fully powered efficacy trial. Identifying strategies to reduce pain and improve physical activity in the context of weight management treatment has the potential to prevent the long-term health consequences of CPO, ultimately leading to a more cost-effective approach to pediatric obesity management. By leveraging the resources of a strong mentorship team and nationally renowned pediatric obesity treatment center, this K23 will provide the PI with skills in (1) pediatric obesity intervention and body composition assessment; (2) physical activity measurement; (3) development and refinement of behavioral interventions; and (4) conduct of clinical trials. The proposed research and training plan will occur within a rich academic environment supported by a multidisciplinary team of highly successful expert researchers and clinicians. This will support the PI’s transition to independence as a pediatric chronic pain intervention researcher with the skills and expertise needed to develop and implement evidence- based behavioral interventions for patients with CPO.

Up to $171K
2031-02-28
health research

Free to search & build · $99 one-time to unlock the application pack · No subscription

Interdisciplinary postdoctoral training in school mental health and school-based prevention science at Johns Hopkins

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NIMH - National Institute of Mental Health

In the wake of a youth mental health crisis, soaring rates of mental disorders have been accompanied by increased demand for child mental health services. Half of children with a mental disorder receive no mental health services. This gap has fueled calls for investments in effective mental health prevention programs in schools. Many mental disorders first onset in childhood, and the benefits of prevention and early intervention are largest when focused near the time of onset. Untreated, mental disorders in childhood can undermine adult mental and physical health, quality of life, educational attainment, and employment. Research shows that coordination, collaboration, and alignment between health and educational sectors are essential to the implementation and sustainability of effective mental health interventions in schools. However, focused training for scholars who want to build research careers at the intersection of health and education is lacking. Advancing the science and practice of school-based prevention of mental disorders requires a fundamentally new, interdisciplinary approach to training. The goal of this first-of-its-kind training program is to equip postdoctoral scholars to become leaders in school mental health and school-based prevention science, leveraging resources across the Johns Hopkins University Schools of Medicine, Public Health, Nursing, and Education. To accomplish this goal, participants will receive rigorous training and high-quality mentorship in 1) frameworks and effective practices in school health; 2) fundamentals of prevention and implementation science; and 3) rigorous research designs and analytic methods for school mental health. Trainees will receive focused training in all three competency areas and tailor the program to their specific area of interest. Trainees without previous graduate training in health research can undertake coursework leading to a Master of Science degree in public health. Trainees will participate in a biweekly Science of School Health T32 seminar that includes career development and professional skills and integrative activities to complement didactics. Administratively housed in the School of Medicine’s Department of Pediatrics, the program’s three trainees per year will come from any of the participating schools. Trainees will be intensively mentored by an experienced and dedicated group of 20 Core Faculty. The program’s four MPIs are national leaders in school health, public mental health, prevention science, quantitative methods, community nursing, and education. The MPIs will be supported by a three- member External Advisory Committee to ensure the program best meets the needs of trainees and the field. The training program will ensure there is a robust pipeline of scholars prepared to lead the next generation of rigorous school-based mental health research; trainees will complete the program with the tools they need to transition to career development awards, and ultimately to independent research careers that address this critical need.

Up to $289K
2031-06-30
health research

Free to search & build · $99 one-time to unlock the application pack · No subscription

Internships at the Northeast Regional Office

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National Park Service

Internships at the Northeast Regional Office: Works with the Regional Historian and National Register Historian on National Register of Historic Places nominations as well as related documentation projects such as Determinations of Eligibility, and Cultural Landscape Inventories for parks in the Northeast Region of the National Park Service. Duties include: researching historic resources; possible site visits and field work to document the resources through descriptions, photographs, and maps; preparation of official correspondence and packages for National Register Nomination documentation. May also prepare brief, interpretive materials for recently completed National Register documentation. Working knowledge of American History, and some experience with the National Register of Historic Places and the Secretary of the Interior's Standards for Rehabilitation beneficial. Working knowledge of graphics programs (Adobe Photoshop & InDesign) also beneficial. Opportunity for candidates with an interest in American history, historic preservation, public history, with a focus on NPS sites. Position located at the Boston office located at 15 State St., Boston MA (600 hours) The intern will work with National Park Service Staff in the Northeast Region History Program, and parks across the Northeast Region, to support public history and community outreach projects related to ongoing historic resource studies on Reconstruction and Segregation during the Jim Crow era, as well as interpreting historic house museums. Duties may include supporting project management through managing records and correspondence, providing historic context for historic research projects, and developing proposals for engaging interpretive products for public audiences based on these research projects. Additionally, intern will support daily operations of Northeast Region History Program, including peer reviewing historic studies, researching and writing short articles about topical and innovative history projects happening across the Northeast Region, and leading informational and educational webinars for park staff on hot topics and key skills in historical practice. Experience and training in one or more of the following required: public history, interpretation, history/ social studies education, museum education, or a related field. Experience working with public and especially youth audiences in history and historic preservation preferred. Position located at the Boston office located at 15 State St., Boston MA (600 hours). This project will provide 600 hour internship opportunities to three candidates.

$1 – $36K
rolling
Education

Free to search & build · $99 one-time to unlock the application pack · No subscription

Investigating the Impact of Housing Assistance on Youth Emotional and Behavioral Health and Mental Healthcare Utilization: An evaluation of the PHLHousing+ Project

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NIMH - National Institute of Mental Health

Expanding upon the parent PHLHousing+ Study (5R01NR021122-02), the overarching goal of this proposal is to test whether interventions addressing housing insecurity as a modifiable social determinant of health (SDOH) improve youth mental health outcomes and outpatient service utilization in households of low-income renters in Philadelphia. This objective is aligned with the strategic aim of the NIMH (Goal 3) to identify opportunities to implement interventions that target modifiable SDOH (see Strategy 3.3.A). The PHLHousing+ Study comprises three groups, all of whom earn below 50% area median income, have at least one child under the age of 16 years living at home, and are renters: 301 households who receive monthly direct cash payments in lieu of a rental voucher for 3.5 years(Cash group), 169 households who receive a rental voucher (Voucher group), and 711 households on the Philadelphia Housing Authority (PHA) waitlist unlikely to receive rental assistance during the entire study period. Our analytic plan combines Cash and Voucher groups into a single Intervention group. Of the 1,181 households in the study, 95.4% are headed by single women and 86.3% are Black. There are 1,965 children in the sample, ranging in age from 3 to 15 years at baseline (M= 8.66, SD= 4.70). Monthly cash payments range from $89 to $2079, with a median payment of $881; payments vary based on household income, family size, and fair market rent. All three groups are surveyed every six months for four years; the first wave of online surveys was deployed in August 2022. Existing surveys include measures of youth emotional and behavioral problems (EBP) reported by primary caregivers. Recent approval from Philadelphia’s Department of Behavioral Health and Intellectual Disability Services (DBHIDS) allows us to pair the repeated survey assessments with de-identified Medicaid claims data for youth participants. I hypothesize that Intervention group youth will demonstrate significant decline in EBP and rates of clinically significant EBP (indicated by increased rates of symptom remission) over time compared to Control group youth (Aim 1). I hypothesize that a subsample of Intervention group youth with clinically significant EBP will be significantly more likely to initiate and retain use of outpatient mental health services compared to Control group youth (Aim 2). Study findings will inform research and policymakers of broader social and health benefits of economic interventions targeting housing as a SDOH. My fellowship training at the University of Pennsylvania will leverage extensive mentorship, coursework, workshops, and seminars. With guidance from a strong mentorship team (Drs. Jaffee, Reina, Mandell, Candon, and the Penn BAC), my proposal and the accompanying training plan provide an ideal foundation for my planned career as an independently funded, leading clinical scientist studying mental health policy and evaluating the implementation of social programs that might affect mental health and service use.

Up to $50K
2029-04-30
health research

Free to search & build · $99 one-time to unlock the application pack · No subscription

Joint Meeting on Youth Prevention, Treatment, and Recovery

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NIDA - National Institute on Drug Abuse

Project Summary- Abstract Adolescent and emerging adult (youth) substance use disorders present a major public health problem in the United States and result in a variety of negative consequences when left unresolved, including early mortality. Despite these harms, there is a lack of strong prevention programming, a shortage of developmentally- appropriate and accessible treatment for youth, and inadequate community supports and recovery programming. We need collaborative urgency, action, and innovation across disciplines and key stakeholders to address the current substance use crisis in our nation. This proposal seeks funding to support our annual Joint Meeting on Youth Prevention, Treatment, and Recovery (JMYPTR). JMYPTR serves as a platform for all key stakeholders including, researchers, trainees, practitioners, policymakers, and youth and their families. JMYPTR provides a forum to gather, learn, and share information about evidence-based and innovative practices and research for the prevention of substance use as well as to address questions related to enhancing treatment and recovery support services’ attractiveness and effectiveness for youth affected by substances. Through JMYPTR we seek to closely connect research, clinical interventions, and policy at the state, regional, and national levels by bringing all these key stakeholders together in one meeting. Despite the relatively recent launch of JMYPTR in 2024, there is a strong history behind the meeting as it builds on the foundation of the Joint Meeting on Adolescent Treatment Effectiveness (JMATE), which ran from 2005-2012. Our National Center on Youth Prevention, Treatment and Recovery (NCYPTR) at the Massachusetts General Hospital Recovery Research Institute, in collaboration with numerous federal, state, and national organization partners, has revamped efforts to address the public health imperative of confronting youth AOD use by hosting the annual JMYPTR. Our 2026 JMYPTR and our plans for future conference years aligns with the NIDA priorities outlined in the 2022-2026 Strategic Plan by focusing on several key aspects of research and practice. JMYPTR’s emphasis on advancing the training of the next generation of scientists as a cross-cutting NIDA priority is also at the forefront of our planning. This is represented in this R13 request for travel awards to support early career scholars, including high school students. We anticipate that the new networks and sharing of information built through this conference will help stimulate and produce a new generation of enthusiastic youth-focused substance use investigators and lead to significant and innovative research proposals in the years to come.

Up to $25K
2031-04-30
health research

Free to search & build · $99 one-time to unlock the application pack · No subscription

JUVENILE REDEPLOY

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National Youth Advocate Program

Politics and Civic Affairs Services

2028-06-30
Community DevelopmentHealth

Free to search & build · $99 one-time to unlock the application pack · No subscription

Maternal Traumatic Stress and Youth Alcohol Use

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NIAAA - National Institute on Alcohol Abuse and Alcoholism

PROJECT SUMMARY/ABSTRACT The candidate’s long-term goal is to develop a research program focused on how intergenerational trauma contributes to alcohol use in youth, and thereby facilitate the development of improved strategies to prevent alcohol use disorder (AUD) in youth. Through the research and training in this K08 proposal, the PI will acquire training in longitudinal research methods, AUD clinical and neural correlates, and task-evoked functional MRI (fMRI) connectivity. Youth alcohol use is a serious public health problem that is related to family functioning. Maternal history of post-traumatic stress disorder (PTSD) may increase youths’ likelihood of alcohol use and later risk for AUD by influencing youth neurobiology. Heightened response to negative emotions is an important predictor of later AUD in youth and is also associated with family history of PTSD. Associations between maternal history of PTSD, youths’ neurodevelopment, and prospective youth alcohol use have been minimally examined. Addressing this gap in knowledge would support the ability to successfully prevent or mitigate the emergence of AUD in offspring of mothers with a history of PTSD. Therefore, the proposed K08 project will address the candidate’s training goals while gathering preliminary and feasibility data supporting the next step in her research. The proposed research study aims to: (1) evaluate differences in alcohol use among youth with or without a maternal history of PTSD, during a 2-year follow-up period; and (2) among these same two groups, evaluate differences in task- based functional connectivity among brain regions involved in emotion response and corresponding behavior. The PI proposes to accomplish these aims by collecting fMRI and report-based data from a sample of 56 youth ages 12-14, and their mothers with histories of trauma exposure. Half of the youth will have a mother with a history of PTSD, and the other half will not have a mother with a history of PTSD. Youth will complete a fMRI paradigm designed to elicit activity in brain regions underlying emotion response. Youth will complete follow-up assessments every 6 months across 2 years. It is anticipated that findings will show the extent to which maternal PTSD is associated with youth alcohol use, and with disruptions in youth emotion response system function as a potential mechanism. This K08 application proposes training and research that is directly in line with NIAAA objectives and represents a logical progression from the PI’s prior experience to address career development goals in three areas: (1) longitudinal participant retention and analytic techniques in alcohol use research; (2) assessment of clinical and neural correlates of AUD; and (3) advanced functional MRI connectivity methods in developmental models of AUD. The experience and findings from the proposed K08 will position the PI to pursue NIH funding and build this line of research through a large developmental study of AUD risk.

Up to $164K
2031-04-30
health research

Free to search & build · $99 one-time to unlock the application pack · No subscription

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