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Alabama State Council on the Arts

The Alabama State Council on the Arts provides general operating support grants to established arts organizations across Alabama, funding programming, staff, and operations that deliver arts and cultural experiences to communities.

Alaska State Council on the Arts

ASCA provides grants to arts organizations and community groups for arts programming, arts education, and cultural activities that enrich the lives of Alaskans and support the state's creative economy.

Alberta Foundation for the Arts

AFA provides grants to support the development of arts and culture in Alberta through project grants, operating grants, and individual artist grants.

Albuquerque Community Foundation

Albuquerque Community Foundation ($150M in assets) supports nonprofits in NM through grants focused on education, community development, health, arts. Awards range from $1,000 to $50,000.

Meany Center for the Performing Arts

At this time when social issues like inequality divide us, five Seattle community-based artists and acclaimed artist Daniel Alexander Jones invites our community to a free public art event to meditate on wholeness with a ritual performance, dance and music celebration. The public is invited to a community processional performance, to activate new temporary altar art pieces in Public Spaces, discover movement meditations+ cultural tradition. The celebration kicks off the start of an art exhibit at The Henry Museum. The event is set during the U. District fair, to draw broad community participation, open to everyone. This art activation event features Timothy White Eagle, Valerie Curtis-Newton, Leon Finley, Afroditi Psarra, Althea Rao, who explore forces that shape our reality, linking waves of history, and the public meeting places which have served as contemplative sites in world cultures. Participants are invited to fill out a MEMORY card for an ongoing art installation.

Amarillo Area Foundation

Amarillo Area Foundation ($800M in assets) supports nonprofits in TX through grants focused on education, health, community development, arts. Awards range from $2,500 to $200,000.

National Endowment for the Humanities

AMERICA250 COMMISSIONS CELEBRATING AMERICA PROJECT [THE AMERICA250 COMMISSION TRAVELING MUSEUM PROJECT WILL BE THE FIRST OF ITS KIND FOR THE ARIZONA SECRETARY OF STATE?S (AZ SOS) OFFICE. IT WILL ENTAIL MULTIPLE ACTIVITIES HONORING THE FOUNDING OF THE UNITED STATES OF AMERICA AND THE PRINCIPLES OF THE DECLARATION OF INDEPENDENCE. PROPOSED ACTIVITIES INCLUDE TOURING ARIZONA?S REPLICA LIBERTY BELL, HISTORICAL DOCUMENTS, ART PIECES, AND INTERACTIVE EXHIBITS IN ALL 15 COUNTIES THROUGHOUT ARIZONA.]

American Samoa Council on the Arts

Arts and cultural grants for organizations in American Samoa, supported by NEA federal funding.

NICHD - Eunice Kennedy Shriver National Institute of Child Health and Human Development

ABSTRACT The multinucleated syncytiotrophoblast (STB) is a tissue-sized single cell that separates the maternal and fetal vasculature during pregnancy. The STB wraps around the villous trees of the placenta lobules, encasing them in a cell with billions of nuclei in a common cytoplasm. This giant single cell facilitates the exchange of nutrients, is essential for fetal immunoprotection, is the primary producer of pregnancy hormones, and performs critical metabolic roles. Further, the STB must simultaneously respond to gradients in oxygen, nutrients, maternal hormones, and pathogens that fluctuate in space and time. How does a single cell support these diverse homeostatic tasks and simultaneously respond to local stresses? We hypothesize that the multinucleate organization is fundamental to supporting the many demands of production, metabolism, and stress response required of a single STB cell. Recent work and our preliminary data show that individual nuclei within the STB indeed have distinct transcriptional programs despite all sharing the same cell cytoplasm. This indicates that STB nuclei are heterogeneous in activity and function. Notably, GO terms for each of the STB nuclear clusters show mutually exclusive expression of homeostatic STB functions or stress response genes. Therefore, nuclear individuality could both facilitate the myriad of STB functions and the insulation of the stress response by spatially clustering in different regions depending on local functions or conditions. Major gaps in knowledge include how different nuclear identities are spatially patterned in the tissue, how nuclear identities arise mechanistically, and the functional consequences of nuclear heterogeneity within the STB cell. Spatial organization of the STB is disrupted in multiple forms of preeclampsia, a pregnancy disease that stems from improper placentation in the first trimester or maternal inflammation. We predict that the systemic stress seen in preeclampsia perturbs the functional balance and spatial organization of homeostatic and stress response pathways in STB nuclei. The proposed experiments will analyze heterogeneous gene expression in healthy and preeclamptic placentas with the following aims: Aim 1: Dissect the spatial patterns of RNA expression and localization in the STB cell and Aim 2: Identify the function and mechanism of heterogeneous nuclear gene expression in the STB. We will apply state-of-the-art spatial transcriptomics on placentas from healthy and preeclamptic pregnancies to analyze gene expression patterning in different locations of the STB. Using super-resolution, live-cell imaging, and genetic manipulations of placenta organoids, we will determine the mechanisms generating specialized nuclear transcription and the functional consequences of heterogeneous nuclear gene expression. This work will establish a functional atlas of STB nuclear identity patterning in health and preeclampsia and act as a guide to discover molecular drivers of pregnancy disease.

Andrew W. Mellon Foundation

Supports the arts and humanities through grants to museums, libraries, universities, and performing arts organizations. Focus on social justice and racial equity.

Andrew W. Mellon Foundation

Supports humanities, higher education, and arts programs in South Africa.

Andy Warhol Foundation for the Visual Arts

Grants for organizations presenting, curating, and promoting contemporary visual arts.

U.S. Mission to Italy

The U.S. Mission to the Republic of Italy s Public Affairs Section (PAS) is pleased to announce that funding is available through its Public Diplomacy Grants Program. This is an Annual Program Statement outlining funding priorities, strategic themes, and the procedures for submitting requests for funding. PA Italy invites proposals for programs that strengthen cultural ties between the United States and Italy through cultural and exchange programming that highlight shared values and promote bilateral cooperation. All programs must include a significant American cultural element, connection with American expert(s), organization(s), OR institution(s) in a specific field that will promote increased understanding of U.S. policy and perspectives. Priority Program Areas: American and Italian voices countering malign influencers and misinformation campaigns Promoting strong transatlantic relations; Creativity and innovation in education and the arts, and problem solving of issues of mutual interest to both countries; American Studies, particularly American History and Literature, to include university linkages; Promoting diversity and inclusion; Empowerment and prosperity through STEM education and entrepreneurship; American English Language Study; Media Literacy.

U.S. Mission to Tajikistan

Purpose of Public Diplomacy Grants: PDS Embassy Dushanbe invites proposals for programs that strengthen ties between the United States and Tajikistan in priority program areas (see below) in order to highlight shared values and promote bilateral cooperation. All proposed programs must include an American element, either through a connection with American expert/s, organization/s, or institutions/s, usage of American educational/informational resources, or any other activities that promote or contribute to increased mutual understanding between the people of the United States and people of Tajikistan. Competitive proposals will promote continued and sustainable cooperation between the people of the United States and Tajikistan even after the project concludes. Competitive proposals will include partnership with Tajik governmental bodies, and to organizations that have a demonstrated track record of implementing such programs. Examples of programs could include, but are not limited to: Academic or professional exchanges, lectures, seminars, trainings, speaker programs, or workshops; and Artistic, cultural, or sports workshops, masterclasses, joint performances, and/or exhibitions. PDS welcomes proposals that support one of the following priority program areas: TOPIC 1: Counter Gender-based Violence (GBV) Domestic violence (DV) and gender-based violence (GBV) remains a serious issue in Tajikistan and much of the world. In a USAID-funded survey in Tajikistan, 97% of men and 60% of women believed spousal abuse was justified. Cases of GBV and DV are underreported because victims wish to avoid humiliation, reprisal, or social stigmatization, or believe it may have been warranted. Further, authorities wishing to promote traditional gender roles frequently dismiss domestic violence as a family matter or only gave a warning or fine. Government resources for survivors are also limited. Project Audience(s) may include: Religiously or socially conservative communities, especially Tajik men (18-50 years old) High school students (14-18 years old.) Youth and emerging leaders (18-35 years old.) University teachers and students. Labor migrants and spouses of labor migrants. Tajik advocacy groups. Government bodies. Independent media including bloggers and vloggers Countering Gender-Based Violence Project Goal: Empower civil society and communities in Tajikistan to prevent and prosecute cases of Domestic Violence (DV) or Gender-Based Violence (GBV) through community-led initiatives. Project Objectives (may address one or more of the following): Messaging campaigns or awareness raising activities, such as sports diplomacy, should engage and target both men and women. Having men as the face of campaigns, or having men speak to men standing against GBV, demonstrates solidarity and emphasizes that eradicating gender-based violence is the collective responsibility of everyone, regardless of gender. Improve collaboration between civil society, independent media, and the government to identify and address gaps in existing laws and policies that criminalize GBV/DV, provide protections for victims, and establish legal frameworks for persecution. Raise awareness among vulnerable populations about laws, rights, and support services concerning early marriage, domestic abuse, harassment, divorce, alimony, and other civil rights. TOPIC 2: Promoting Women s Economic Empowerment and Entrepreneurship Due to the high rate of male labor migration and unemployment, more Tajik women are exploring ways to financially support their households and communities. However, women entrepreneurs' activities are highly dependent on the effectiveness of the business environment in the country. Moreover, the mountainous regions throughout the country challenge the development of entrepreneurship, as does lack of information, limited access to financing for starting a business, and other socio-economic conditions. Nevertheless, successful small business development creates new employment opportunities in Tajikistan and helps women support themselves and their families. Small businesses are fast becoming the main source of income for women in Tajikistan. Proposed projects should enhance women s participation, promotion, and longevity in the Tajik economy and ability to assume leadership positions. Projects should clearly support the protection of economic rights for women and increase respect for women s rights in society to improve their independence and proactive role in Tajik society. Project Audience(s) may include: Women from rural areas (including the spouses of labor migrants) and women entrepreneurs. Small businesses in rural areas. Business associations. Financial and government institutions. Tourism agencies (including guesthouse and small hotels). Community leaders and youth demonstrating leadership potential in these areas. Women s Economic Empowerment Project Goal: Increase the capacity of women from underserved, rural communities, including the spouses of labor migrants, to participate or increase their participation in the Tajik economy. Improve women's economic opportunities in Tajikistan by increasing the capacity of women to start, establish, or expand their own companies. Project Objectives (may address one or more of the following): Develop the business and technical skills of women in rural communities to increase employability, launch and/or improve their own businesses. Establish and conduct activities with a professional network for women from under-represented communities, including the spouses of labor migrants, to support mentorship relationships and collaborative initiatives among network members that go beyond the conclusion of project activities. o Projects could connect women s entrepreneurship in the development of tourism around newly recognized UNESCO heritage sites. o Increase awareness of tourism initiatives and employment opportunities centered around newly designated UNESCO heritage sites. o Projects could seek to increase participation of women from underserved and target communities in the fields of Science, Technology, Engineering, and Mathematics (STEM). Increase women s knowledge and understanding about their legal rights in society and how to advocate for the respect of those rights. o Increase women s knowledge and understanding about their legal rights in the workplace, including rights related to employment, equal pay, job security, and access to economic opportunities. o Equip Tajik women with the ability to advocate for the recognition and enforcement of these rights. Promote women s economic empowerment and entrepreneurship through support from start-up hubs, corporate social responsibility, and/or access to finance. Emphasis should be placed on strengthening chambers of commerce, entrepreneurs, and core private sector industries through interactions or linkages with U.S. counterparts. o Facilitate access to funding resources and financing opportunities for women entrepreneurs to launch and grow their businesses. o Strengthen organizational capacities of chambers of commerce to support business development of aspiring female entrepreneurs. o Facilitate interactions and linkages between women entrepreneurs, chambers of commerce, startup hubs, and private sector industries in Tajikistan and their U.S. counterparts. TOPIC 3: Sharing America with Tajikistan The United States values innovation, creativity, critical thinking, freedom of expression, democratic principles, economic growth, and security. The United States supports a sovereign and independent Tajikistan, which includes support for a well-informed, discerning public who can inoculate itself against disinformation. Both the United States and Tajikistan have rich cultural traditions as shown in literature and storytelling, theater and performing arts, film, music, dance, sport, and education. Educational, cultural, and other exchange activities are a great way to engage the public, especially at-risk youth and those with neutral views or misconceptions about the United States, in order to bridge our cultures, deepen understanding, and discuss topics of mutual importance. Proposed projects should strengthen understanding between the United States and Tajikistan and advance areas of mutual interest by leveraging the experiences and lessons learned from the United States, while respecting cultural differences. Project Audience(s) may include: Tajik audiences who have not had exposure to the United States before. Youth 16-35. Academia, professors, and teachers. Civil society, non-government organizations, and associations/organizations promoting shared values or areas of mutual interest. Information professionals (media outlets, managers, editors, journalists, influencers). Religious and community leaders. Entrepreneurs and business community advocacy organizations. National and subnational government officials. Project Goal: To share American values, such as freedom of expression, respect for human rights, and celebrate/promote respect for diversity and social inclusion, while also improving access to objective information and increase media literacy and critical thinking skills to analyze mis and disinformation aimed at the United States. Project Objectives (may address one or more of the following): Raise awareness about shared U.S.-Tajik values and partnerships through trainings, workshops, masterclasses, joint performances, or other projects by U.S. and/or Tajik experts. Increase access to American content by Tajik audiences (such as book translations) that promote U.S. democratic and rights-based values. Increase collaboration between local, state, and civil society actors/stakeholders on well-defined social issues affecting both the United States and Tajikistan by sharing U.S. models of government-community engagement, or by working with U.S. experts/peers. Increase the effectiveness of individuals, organizations, and coalitions working to advance and/or advocate for respect and the promotion of human rights. Strengthen the ability of Tajik media professionals to develop accurate and fact-based informational media campaigns through digital skills building and training initiatives based on U.S.-best practices. Increase production and publication of objective, fact-based and editorially diverse media content by Tajik media professionals. Increase critical thinking skills, especially for youth and publics with a neutral or view or misconceptions about the United States, to identify and critically analyze sources of misinformation and disinformation. In addition to the specific requirements listed above by program area, all proposals must: 1. Clearly indicate the primary activity area to which it is being submitted for consideration. 2. Focus on the key public diplomacy audiences and activities specified in the areas, provide programs for underserved geographic regions of Tajikistan, as well as non-elite schools (if applicable); 3. Clearly delineate how elements of their program will have a multiplier effect and be sustainable beyond the life of the grant; 4. Provide a traditional and/or social media plan for marketing program activities and outcome, if applicable 5. Identify the cities/districts in which activities will take place. 6. Identify specific outcomes to be achieved by the end of the grant period. 7. Identify any tools (surveys, beneficiary interviews, focus groups, etc.) that will be developed for Monitoring and Evaluation purposes. Applicants must also demonstrate competency to manage all financial aspects of the project, including participant costs and transparent arrangements of sub-grant relationships with partner organizations, if applicable.

Bureau Of Educational and Cultural Affairs

The U.S. Department of State, Bureau of Educational and Cultural Affairs, Cultural Programs Division (ECA/PE/C/CU) seeks to advance international understanding of American values by exposing foreign audiences to innovative and compelling works of art that reflect promote American values and foster international dialogue on shared global challenges.

Bureau Of Educational and Cultural Affairs

Annual Program Statement for U.S. Presentation at International Art Biennales

Bureau Of Educational and Cultural Affairs

The U.S. Department of State, Bureau of Educational and Cultural Affairs, Cultural Programs Division (ECA/PE/C/CU) seeks to advance international understanding of American values by exposing foreign audiences to innovative and compelling works of art that reflect promote American values and foster international dialogue on shared global challenges.

NIEHS - National Institute of Environmental Health Sciences

Abstract Arsenic is a global environmental toxin and known human carcinogen that contaminates the drinking water of over 200 million people. Despite accounting for host factors such as genetics and diet, there is significant inter- individual variability among similarly exposed individuals in the development and progression of arsenic-related diseases (arsenicosis), including bladder cancer, diabetes, and cardiovascular disease. Emerging evidence implicates the gut microbiome as a key modulator of arsenic toxicity. Notably, evaluation of murine models of human arsenicosis has demonstrated that antibiotic-induced gut microbiome disruption significantly increases arsenic toxicity and recapitulates interindividual susceptibility seen in humans. These findings are concerning because every year ~70% of Americans receive antibiotics that could trigger or exacerbate the long-term health consequences of arsenic. Antibiotic use and microbiome diversity are not part of current risk assessments of arsenic or other environmental toxicants. This project tests the overarching hypothesis that antibiotic-induced disruption of the gut microbiome increases arsenic toxicity and carcinogenesis in vivo. In Aim 1, a humanized mouse model will be used to evaluate how commonly prescribed antibiotics in the US influence arsenic toxicity, using a standardized morbidity scoring system, microbiome sequencing, arsenic speciation analysis, and tissue histopathology. In Aim 2, carcinogenesis of the bladder epithelium will be compared in different groups of microbiome competent and antibiotic-treated mice using an established co-exposure model that combines arsenic with the bladder-specific carcinogen, BBN. These studies will rank antibiotics by their toxicity and carcinogenic potential in the context of arsenic exposure and help define microbiome-targeted strategies to reduce disease risk. A fellowship training plan has been developed around this research that provides a comprehensive, interdisciplinary instruction in toxicology, oncology, microbiome research, and data analysis under the mentorship of experts in these fields. Training goals will be achieved in a highly collaborative and supportive environment with access to state-of-the-art facilities for gnotobiotics, pathology, and microbiome analysis. Completion of this project will enhance the candidate’s understanding of microbiome–toxin interactions in preparation for a successful, independent research career, and holds great potential to significantly improve risk assessment for arsenic and other environmental carcinogens.

National Park Service

United States Department of the Interior, National Park Service (NPS) Notice of Intent to Award. This is not a request for applications. This posting is to provide public notice of the NPS' intention to fund the following project activities without full and open competition: Cooperative Agreement P19AC01031 with the Los Cenzontles Mexican Arts Center, for the project titled, "Anza Expedition Film."

NIDDK - National Institute of Diabetes and Digestive and Kidney Diseases

PROJECT SUMMARY/ABSTRACT Cirrhosis, the late-stage complication of liver disease, stands as a leading cause of death globally and frequently causes kidney dysfunction. Yet, the mechanisms leading to kidney function loss in cirrhosis remain incompletely understood, which in turn limits the development of effective therapeutic options. I have generated data showing subclinical injury to the proximal kidney tubules (PTs) in stable outpatients with cirrhosis irrespective of glomerular filtration rate (GFR), the prevailing clinical assessment of kidney function, suggesting PTs are an early target in cirrhosis that may not be captured by glomerular markers. Contrasting with passive filtration, the tubules depend on kidney cellular energy production for solute secretion and reabsorption. Various pathways have linked cirrhosis to impaired tubular metabolism including mismatched demands for sodium/water reabsorption, exposure to retained bile acids and toxins, and pro-inflammatory gut bacterial products, however further investigation of these early mechanisms is challenged by a lack of measures aligned with the target of injury or studies in patients with cirrhosis already experiencing overt kidney disease. I hypothesize that the collective ischemic and toxic-metabolic environment causes attenuation in kidney cellular metabolism, affecting downstream energy-dependent functions of tubular secretory clearance (TSC) and reabsorption, that is not captured by glomerular markers alone. I propose a prospective nested cohort study of patients with cirrhosis characterized with longitudinal data and biosample collections, multi- modal imaging, and gene expression profiling, to reveal novel pathways of kidney dysfunction and potential therapeutic targets, as well as more holistic assessments of kidney function beyond GFR. I will recruit 140 patients with cirrhosis and preserved eGFR to participate in 3 study visits to determine the association of baseline measures of PT function and injury with kidney-related outcomes (eGFR slope, acute kidney injury [AKI], and ascites severity). I will apply novel methods developed in our lab to estimate TSC by measuring plasma and urine levels of highly secreted endogenous solutes, which I have used in studies of AKI, drug clearance models, and CKD development. In a sub-cohort (N=20) compared to age-matched controls (N=20), I will delineate the effect of cirrhosis on tubular oxidative metabolism using state-of-the-art imaging with 11C- acetate as well as measuring TSC using an exogenous tracer, 99mTc-MAG3. Finally, I will obtain kidney biopsies in a sub-cohort (N=9) of patients with cirrhosis to characterize tubular pathways of injury, metabolism, and fibrosis using a novel spatial transcriptomics platform. As part of this career development award, this work will allow me to develop new expertise in study design, systems biology, and biostatistics, yield a novel cohort and data in patients with cirrhosis to uncover new insights into mechanisms of kidney dysfunction, and provides a basis for future discovery to develop monitoring and treatment strategies as an independent translational researcher of kidney dysfunction in cirrhosis.

NIGMS - National Institute of General Medical Sciences

PROJECT ABSTRACT: Cleveland State University (CSU) proposes to acquire a new liquid chromatography-tandem mass spectrometry (LC-MS/MS) instrument to significantly enhance research infrastructure and educational opportunities. This state-of- the-art instrument is crucial for advancing diverse scientific and engineering disciplines at CSU. It will directly support ongoing NIH-funded research by multiple CSU faculty, fostering interdisciplinary collaborations and leveraging diverse expertise across campus. The proposed LC-MS/MS system's advanced technical capabilities will promote rigorous and reproducible research, upholding high standards for scientific methodology and data reliability, thereby substantially boosting current research output. Furthermore, the increased research capacity afforded by this instrument is anticipated to help additional faculty members secure more federal and private funding. Beyond research, the proposed LC-MS/MS will provide essential hands-on training for CSU's undergraduate and graduate students. This practical experience will prepare them for high-demand careers in analytical and biomedical fields, thereby enhancing and building upon CSU's educational capacity.

Arizona Commission on the Arts

Arizona Commission on the Arts provides grants to support arts and cultural programming, artist fellowships, arts education, and community-based arts projects across AZ.

Arizona Community Foundation

Arizona Community Foundation ($1.2B in assets) supports nonprofits in AZ through grants focused on education, community development, health, arts, environment. Awards range from $2,500 to $200,000.

Arizona Community Foundation

The Arizona Community Foundation awards grants to nonprofit organizations throughout Arizona to address community needs in education, health, arts and culture, human services, and civic engagement.