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Clinical and Translational Science Award (CTSA) UM1 at Columbia University

open

NCATS - National Center for Advancing Translational Sciences

Project Summary Our Clinical and Translational Science Award (CTSA) hub is situated in Upper Manhattan at the Irving Institute for Clinical and Translational Research (Irving Institute) of Columbia University (CU), based at the CU Irving Medical Center (CUIMC). Our evolution as institutional leaders and maturation as a comprehensive CTSA hub enables us to drive innovative clinical and translational science (CTS) and clinical and translational research (CTR), in collaboration with our hospital partner NewYork-Presbyterian. The mission of our hub is to improve the health and wellbeing of patients and communities through our strategic vision and goals to catalyze all phases of CTS and CTR to achieve a fully integrated research environment locally and across the CTSA Program. We now prioritize systematic and deep engagement with all our stakeholders to achieve the greatest impact on research and health through CTS and CTR. Programs and services will be deployed through user-friendly research navigation and optimization using dissemination and implementation science (IS) to inform our cyclical approach to identify, develop, demonstrate, and disseminate (ID3) innovations that address CTR gaps and opportunities. Our record of innovation permeates our education, services, and research and guides our evaluation and continuous quality improvement strategy. CTS innovations are proposed for near-peer mentoring, digital health in communities, data and design, cell therapeutics, research core utilization, health system- embedded trials, federated learning, artificial intelligence (AI) and return of research results to participants. Irving Institute leaders are integrated into CUIMC governance to successfully implement our vision and goals. Module B Strategic Management approach and infrastructure will be optimized to catalyze CTS innovations. The ID3 approach, enhanced by tailored engagement and IS, will integrate institutional and community priorities, stimulate CTS innovations across the T0–T4 spectrum, and broadly disseminate services and programs with greatest potential to address major CTR gaps. Through personalized training, Module C1 will create and expand models to train a skilled, interdisciplinary workforce to advance rigorous CTR and CTS and enhance participation of the workforce and communities in CTR. Module C2 will deploy bidirectional engagement with our community ambassadors, patients, and local communities to develop and disseminate programs that address community priorities to improve health. Modules D1 and D3 will use research navigation and optimization to develop and cyclically refine research-friendly service programs as well as innovations in AI, informatics, precision medicine, and federated learning to accelerate CTR and CTS. Through our Module D2 Pilots and Element E CTS Program, we will work directly with stakeholders to tackle major CTS challenges, such as a system for return of individual results to research participants as well as opportunities in cell therapy, -omic core utilization in CTR, and AI in research, operations and health. Through these innovations, our hub will drive research efficiency, quality, and impact and align with CTSA Program goals to deliver more treatments to more patients more quickly.

Up to $10.7M
2033-05-31
health research

Free to search & build · $99 one-time to unlock the application pack · No subscription

Community Services Block Grant (CSBG) Communities of Practice (COP)

upcoming

Administration for Children and Families - OCS

<p>The Office of Community Services (OCS) within the Administration for Children and Families (ACF) will support a funding opportunity for six (6) three-year cooperative agreements for the Community Services Block Grant (CSBG) Communities of Practice (CoP).</p><p>Six CoPs will be established to provide training and technical assistance (TTA). These CoPs will include CSBG-funded states, territories, and tribes, and CSBG state associations and eligible entities. The specialized TTA must: account for regional, state, city, county, tribal, and community characteristics (i.e., jurisdictional levels, demographic categories, socioeconomic tiers, community resources, etc.); be based on evidence-informed TTA models specific to the assigned CoPs; and include scalable approaches that states, territories, state associations, tribes, and CSBG-eligible entities can implement to support individuals and families with low incomes as they&nbsp;progress towards economic security.</p><p>The six award recipients will be required to provide their respective grouping of CSBG states, territories, tribes, state associations, and eligible entities&nbsp;with capacity-building that creates scalable, evidence-informed interventions that improve earned income, employment stability, and asset development for families with low incomes through coordinated service delivery and systems alignment.</p><p>TTA developed under these CoPs will advance community-level strategies that prevent and reduce barriers to attaining economic mobility; education and workforce development; transportation; and access to safe and stable housing, including support for the A Home for Every Child administrative priority. Each CoP is expected to invest in partnerships to support data-driven decision-making and infrastructure that strengthens service delivery, enhances reporting and compliance, and reduces opportunities for fraud, waste, and abuse across the Network.</p>

$725K
2026-08-03
income_security_and_social_services

Free to search & build · $99 one-time to unlock the application pack · No subscription

Community Services Block Grant (CSBG) Communities of Practice (COP)

upcoming

Administration for Children and Families - OCS

The Office of Community Services (OCS) within the Administration for Children and Families (ACF) will support a funding opportunity for six (6) three-year cooperative agreements for the Community Services Block Grant (CSBG) Communities of Practice (CoP).Six CoPs will be established to provide training and technical assistance (TTA). These CoPs will include CSBG-funded states, territories, and tribes, and CSBG state associations and eligible entities. The specialized TTA must: account for regional, state, city, county, tribal, and community characteristics (i.e., jurisdictional levels, demographic categories, socioeconomic tiers, community resources, etc.); be based on evidence-informed TTA models specific to the assigned CoPs; and include scalable approaches that states, territories, state associations, tribes, and CSBG-eligible entities can implement to support individuals and families with low incomes as they progress towards economic security.The six award recipients will be required to provide their respective grouping of CSBG states, territories, tribes, state associations, and eligible entities with capacity-building that creates scalable, evidence-informed interventions that improve earned income, employment stability, and asset development for families with low incomes through coordinated service delivery and systems alignment.TTA developed under these CoPs will advance community-level strategies that prevent and reduce barriers to attaining economic mobility; education and workforce development; transportation; and access to safe and stable housing, including support for the A Home for Every Child administrative priority. Each CoP is expected to invest in partnerships to support data-driven decision-making and infrastructure that strengthens service delivery, enhances reporting and compliance, and reduces opportunities for fraud, waste, and abuse across the Network.

$725K
2026-08-03
social services

Free to search & build · $99 one-time to unlock the application pack · No subscription

Community Volunteer Ambassador Program

open

National Park Service

A. Project Goals: The primary goals of this Task Agreement are to increase the number and diversity of community members engaged in NPS programs, activities and events through expanded volunteer, partnership, and service learning opportunities; to develop the next generation of lifelong conservation leaders, stewards and supporters; and to develop a skilled and diverse workforce pipeline for the NPS and surrounding communities by providing Community Volunteer Ambassadors (CVA) with the comprehensive training they need to develop relevant and transferable skills and knowledge. B. Project Objectives: This project goal will be achieved by completing the following objectives. Up to 82 Community Volunteer Ambassador Interns (hereafter referred to as Interns) will be annually recruited, selected and placed in NPS park sites and program offices nation-wide. The NPS National Volunteer Program Office will work with Regional Volunteer Offices to determine which parks and programs would most benefit from additional support when choosing where to place Interns. Interns will gain new skills and experience through year-round formal and informal training, enabling them to build a portfolio of professional skills and develop a community of support. Interns will work with their supervisor to strategically reach out to and engage community constituents that represent diverse age groups and cultures. Interns will work with park and program employees to expand the number and variety of available volunteer programs, activities, and events, providing community members an opportunity to learn about park resources through active engagement in research, restoration, maintenance and visitor service projects. New positions/projects will create opportunities for people of all ages to become involved in episodic, short and long-term educational, skill-building, career-enhancing and rewarding volunteer experiences. The number of NPS sites engaged in national days of service will increase, with more parks and offices participating in volunteer work days and recognition events. National days of service are annual, system-wide and multi-agency service days, including The Martin Luther King Jr. Day of Service, National Trails Day, National Public Lands Day, and National Volunteer Week. Selected parks will participate in service-wide efforts to engage communities around national and local events, park anniversaries, and holidays, including Veterans Day, Memorial Day, September 11 Day of Service, and Labor Day events. More parks and programs will participate in national volunteer programs including Veteran s programs, Healthy Park Healthy People programs, Trails &amp; Rails programs, Bark Ranger programs, youth programs, and Artist-in-Residence programs Interns, volunteers and supervisors will work together to develop and institute a way to track statistics related to outreach and community engagement goals.

$1 – $2.8M
rolling
community development

Free to search & build · $99 one-time to unlock the application pack · No subscription

Conserving the Future

open

Fish and Wildlife Service

The National Wildlife Refuge Association proposes to do the following: 1. Building Grassroots Partnerships: Enhancing training and support for Refuge Friends groups that are well positioned to assist the System. This includes focused work with a subset of Friends Groups that are poised to grow and can mentor others, and developing Friends capacity to help urban and highly-visited refuges thrive. 2. Collaborative Landscape Conservation: Implementing Strategic Habitat Conservation through the Beyond the Boundaries landscape conservation programs, as envisioned by Conserving the Future. 3. Supporting the Urban Wildlife Refuge Program: Assisting with communications strategies, program development, sharing lessons learned and building community engagement around a subset of urban refuges. 4. Raising the Profile of the Refuge System: Developing a branding and communications strategy that better connects the American public with the Refuge System. 5. Youth engagement and career development: Building the National Tigers for Tigers Coalition as a voice for the international conservation efforts by working on behalf of the goals and objectives of the U.S. Fish and Wildlife Service s Multi-national Species Conservation Fund and developing internships and workforce training opportunities for college students at T4T Universities and support the adaptation of Beyond the Boundaries strategies to conserve important tiger landscapes in Asia.

rolling
Education

Free to search & build · $99 one-time to unlock the application pack · No subscription

Cooperative Agreement Between the U.S. Fish &amp; Wildlife Service and American Trails

open

Fish and Wildlife Service

Task 1. Redesigning Website for Easier Search and Navigation Functions Starting in the late 1990s, American Trails (AT) began a collection of online trail resources documents, web pages, and links for the trails community to utilize. This collection has grown to over 6,000 pages, all stored in static, HTML code that requires manual updating. While this method worked for us for many years, the mass amount of resources has led to a website that is loaded with information, but that can be difficult to navigate. A user may have to click through multiple pages to find a given resource. Our current search method, using Google indexing, can be helpful, but as a keyword-only search method, it often returns dozens of pages of articles for the user to sort through. AT proposes building a single, powerful Content Management System (CMS) to organize and store these resources a system that will be powerful, fast, clear, and simple to use and that will provide an unparalleled resource library for the trails community including FWS users who have requested better access to information on the American Trails website. The Trail Resource CMS we propose will provide detailed search options title, State, Agency, category, keywords, and full article text search of thousands of American Trails resources. Updating the website will make it easier for the American people as well as FWS employees to better help navigate the most current up to date information on wildlife trails, refuges, and considering habitat in trail planning, construction and maintenance. By updating to the CMS American Trails will be able to better organize data, make it more accessible and easier for FWS to look up information and find trail resources. Task 2. National Recreation Trails National Recreation Trails may be designated by the Secretary of Interior to recognize exemplary trails of local and regional significance in response to an application from the trail's managing agency, such as a management unit of FWS. Through designation, these trails are 5 recognized as part of America's national system of trails as authorized by the National Trail System Act of 1968 (Public Law 90-543). The FWS vision document Conserving the Future: Wildlife Refuges and the Next Generation recommends creative thinking about enabling visitors to learn about FWS resources: "We must actively encourage and provide new opportunities for people of all ages and backgrounds to connect with nature by visiting their national wildlife refuges, personally or virtually." Trails in particular can provide the low-impact managed use that can help meet FWS goals for the future. Designation of trails on FWS lands as NRTs has been identified by FWS staff as a way to encourage visitation of trails that would benefit from increased attention. Trails are a critical way that visitors discover the beauty, history, and natural heritage of the National Wildlife Refuge System, and NRT designation is a cost-effective way to provide visibility to Refuge resources. The NRT website and database are essential tools for reaching the public with up to date information on FWS trails and other recreation opportunities. In 2015, analysis of website visitation documented that 40,446 trails were searched and located using the database on average, per month, by the public. In addition, visitors printed out 5,636 trail records from the database. The cost for updating these online resources is minimal compared to traditional public information techniques such as staffing visitors' centers, printing brochures, and attending public events. Most of the FWS NRTs designated in 2008-2015 have included good information in their applications that can be used for website creation and to populate the NRT designation. However, older designations are typically sketchy with details. Information that is of most use to visitors includes trail description, directions to trailheads, points of interest, and related activities. Helping visitors know the trail location relative to cities and highways is also important, and this can be done both descriptively and via downloadable maps (provided by the Refuges). The database records also should link to Refuge websites where news, events, and current conditions are available. Finally, a photo gives a good identity to the trail and makes it more appealing as visitors search the database. Most Refuge websites do not provide much information on trails. The Featured NRT website pages are an opportunity to provide useful visitor information in an attractive article format that includes trail features, seasonal interest, route descriptions, photos, and digital maps. FWS identifies "special attention to opportunities offered for youth and people with disabilities" as a priority for visitor information. Finally, these pages are also a great way to recognize volunteers and Friends groups who help with construction, maintenance, and interpretation. All FWS-managed National Recreation Trails are good candidates for new Featured NRT pages. We will continue to identify which of the NRTs do not have an existing Internet presence. All of these pages will link to agency and nonprofit websites supporting the trails. Task 3. National Trails Training Partnership (NTTP) Refuge Managers need to build sustainable, cost-effective trails that provide the public with memorable experiences of wildlife and natural areas. Expertise in trail development and management, especially in important habitat areas, needs to reach staff as well as volunteers and cooperating organizations. The US Fish &amp; Wildlife Service is a party to the 2011 memorandum of understanding for the National Trails Training Partnership (NTTP), which is an extension of the 2003-04 agreements that began this initiative to promote trail-related training. The current MOU among seven Federal agencies and 24 national organizations states: "The purpose of this MOU is to develop and expand a framework of cooperation among the Parties at the national, regional, State, and local levels for planning and implementing mutually beneficial projects, activities, and programs for workforce development, training, and education associated with trails and related outdoor recreation and transportation activities." With efforts to promote public health and engage youth in natural resources by building and promoting trails and greenways, the environmental issues are increasingly important to planners 7 and managers. An important way to reduce visitor impacts is to improve planning of trails in habitat areas and use best practices for building and managing trails. Quality trails also facilitate environmental education as well as resource protection. The NTTP website, developed and maintained by American Trails, is a key element in making available resources to help in developing and managing trail systems. This website is available to trail building and management agencies and organizations, as well as to members of the general public who are interested in trails training. Another task is providing resources to help improve accessibility to public lands. Our goal is to provide effective technical information on building better, more sustainable trails, which also increases the level of accessibility. NTTP has also been effective in promoting best practices as well as identifying training providers. Federal agencies, organizations, and States have worked together through NTTP to improve coordination on training nationwide. Specific training available from a variety of providers includes skills for conservation and youth corps organizations, curricula for college-level students, and training to address local needs of agencies and organizations. Task 4. Technical Assistance Technical assistance and information sharing for FWS staff and cooperating organizations is essential to providing attractive as well as cost-effective recreation facilities. The key issues are effective delivery of technical information, improving accessibility, and managing visitor facilities in habitat areas. The FWS vision document Conserving the Future encourages new technology for sharing information and connecting with the public. Recommendation 15 states: "Develop integrated mechanisms for using web-based and other emerging technologies to store and share data, communicate within the System, and inspire and educate visitors and the public." Technical assistance also involves documenting the experience of staff who are retiring. Conserving the Future states: "As we transition from an older to a younger workforce, we must look for ways to transfer knowledge from senior staff." The key challenge for Refuge Managers is how trails can best be built while recognizing the needs and sensitivities of wildlife and the environment. We need to look at good examples on the Refuges, identify best practices in place in other jurisdictions, and document how new or improved trails contribute to both conservation and environmental education. As trails become even more popular, and are the subject of efforts to promote public health and outdoor activity, environmental issues are increasingly important. The desired result is to enable Refuge managers to build the best, most cost-effective trails. While trails may seem like simple projects, managers may not be experienced with state-of-the-art practices. Managers need the technical knowledge to make decisions on surfacing, maintenance, and facilities, as well as management issues of habitat impacts, seasonal closures, and wildlife watching. Providing the best information, as well as contacts with other trail managers on similar projects will lead to the most effective problem solving for trail development. It is also important to manage trails and visitors in ways that reduce impacts while increasing positive experiences and learning opportunities. Refuge managers and others in the field of parks and outdoor recreation need effective technical information on building better, more sustainable trails, which are also increasing the level of accessibility. With years of confusion and uncertainty over actual requirements for accessibility, many agencies have either ignored the need for more accessible trails, or have avoided tackling new trail projects. With the recent publication of final regulations for trails and facilities on federal land there is a critical need to interpret, publicize, and share information on accessible trails. To provide better assistance with trails in habitat areas, we need to continue development of the website area for "Planning Trails with Wildlife in Mind: A Handbook for Trail Planners. Material from the original print publication by Colorado State Parks has been adapted by American Trails to an online presentation at: www.americantrails.org/wild/default.htm. The goal of the Handbook and the new website area is to help planners and managers create trails that make a positive contribution to stewardship of open space and habitat. It is still the only 9 comprehensive resource that details both the impacts and benefits of trails as visitor management tools. Planning Trails with Wildlife in Mind was intended to encourage new contributions and add to the body of knowledge to improve our planning efforts. When it was compiled in 1998, the subject was just beginning to be studied. We need to involve FWS staff in expanding this information source with examples from the Refuges. We also need to make this information available to the public, volunteers, and environmental education providers. Task 5. International Trails Symposium The American Trails International Trails Symposium is the best opportunity for a comprehensive learning experience on all aspects of trail planning, development, and management. The 2017 Symposium will be held in Dayton, Ohio May 7-10, 2017. Over many years of attending the Symposium, FWS representatives have been able to share success stories with trail and greenway advocates, managers, planners, and users, as well as tourism and business interests. American Trails sponsors the International Trails Symposium every two years, The Symposium offers ways to publicize the FWS mission and resources, as suggested in Conserving the Future: "We must also look for ways to build relationships with people who have not had traditional links to wild lands and wildlife, and encourage them to visit refuges." The Symposium is also an important opportunity for FWS representatives to learn from, share success stories, and network with staff of other agencies, communities, and trail organizations. The goal is to create a culture of stewardship for our public lands as well as connections from our communities to nature. This Symposium will continue to build on previous conferences that have offered a variety of presentations on the topic of trails and wildlife. With an increasing need for solving problems and creating more cost-effective and sustainable trails, the theme for the 2017 Symposium is Trails Take Flight: Connecting People, Places, and Possibilities. Symposium programs will explore the many pathways to success for all types of trails, from cities to the backcountry, including trail design, sustainability, safety, advocacy, and health, as well as possibilities for the future. This Symposium will address the need for more technical training through a new partnership with the Professional TrailBuilders Association. We will offer a series of Sustainable Trails Workshops and programs during the Concurrent Educational Sessions, featuring solutions-based topics. In addition, Mobile Workshops will bring attendees to featured Dayton, Ohio area sites to share lessons learned from trail planning, partnerships, maintenance, and visitor management. Task 6. International Trails Symposium Hulet Hornbeck Emerging Leaders Scholarship Program Given the spectrum of challenges surrounding human health, underserved communities, and disengaged youth, there is an important need to enable more young people to have the valuable educational experiences such as attending the International Trails Symposium. The Hulet Hornbeck Emerging Leaders Scholarship Program was launched in 2013 as part of the American Trails International Trails Symposium. The program was named in memory of lifelong trail activist Hulet Hornbeck. At the 2013 International Trails Symposium, American Trails provided scholarships to 18 talented young leaders and recently brought 16 talented young adults to the 2015 International Trails Symposium on scholarship. Recipients were immersed in learning best practices and trends in the field to help pave the path to careers in trails, conservation, and outdoor recreation. Many attendees met and mentored these aspiring young trail professionals at the Symposium to encourage them on their way to becoming tomorrow s trail leaders. Diversity and inclusivity are important aspects of the Hulet Hornbeck Emerging Leaders Scholarship Program. This initiative was developed to provide unique training and mentoring opportunities to inspire young adults to choose a career path so they can leave a lasting legacy in the field of natural resources. Scholarship candidates are young adults who have an interest in trails, conservation, and outdoor recreation, and are interested in learning about these as potential career paths. See more on the accomplishments of this program in Youth Scholars Assessment of 2013 International Trails Symposium. Involvement in the Symposium also exposes young professionals to multi-generational dialogue about conservation and recreation. Diversity and inclusivity are important to us so that we can meet everyone s deepest needs, values, and long-term interests. We welcome individuals of all backgrounds to apply regardless of past trails experience. We are more interested in potential. During past Emerging Leaders programs, established resource professionals benefitted just as much from the exchange as the field looks to foster new leadership. onserving the Future clearly states the concern facing Federal land management agencies as well as organizations such as American Trails: "We are an overwhelmingly white and aging organization that struggles with being relevant in this rapidly changing society." The FWS vision document expands on the agency's commitment to student and youth programs in Recommendation 22: "Recruit and retain a workforce that reflects the ethnic, age, socioeconomic, and cultural backgrounds, and language diversity of contemporary America." A mentor pairing for every scholarship recipient (whom share a common interest/career goal) ensures that he or she will reap lasting benefits from the experience. These future leaders will learn best practices and trends in outdoor recreation and resource conservation to help pave the path to careers in these fields. An unexpected outcome of the successful 2015 program was that established resource professionals benefitted as well from sharing their expertise and in looking to foster new leadership in their own agencies. Authorizing statues for this program include Fish and Wildlife Conservation Act of 1934 (16 U.S.C. 2901-2911); Fish and Wildlife Act of 1956 (16 U.S.C. 742(a)-754); Refuge Recreation Act of 1962 (16 U.S.C. 460k-460k(4)); National Wildlife Refuge System Administration Act of 1966 (16 U.S.C. 668dd); Youth Conservation Corps Act of 1972 (16 U.S.C. 1701-1706); Archaeological Resources Protection Act of 1979 (16 U.S.C. 470aa-47011); The National Wildlife Refuge System Act of 1997 (Public Law 105-57); National Wildlife Refuge System Volunteer and

$1 – $60K
rolling
community development

Free to search & build · $99 one-time to unlock the application pack · No subscription

CTSA Postdoctoral T32 at the University of Pennsylvania

open

NCATS - National Center for Advancing Translational Sciences

CTSA Postdoctoral T32 at Penn: Project Summary/Abstract Despite unprecedented scientific breakthroughs, critical delays persist between discovery and clinical implementation. Penn’s CTSA Postdoctoral T32 Program addresses this challenge by training clinical and translational science (CTS) investigators equipped to efficiently translate discoveries into patient care and prepare them for careers in academic medicine, industry, nonprofits, and government agencies. Penn's unique ecosystem as birthplace of mRNA therapeutics and cell/gene therapies provides living examples of successful bench-to-bedside translation. Building on our successful TL1 program that trained 49 postdoctoral trainees with 89% continuing in CTS careers, this dedicated T32 leverages the Institute for Translational Medicine and Therapeutics Education program's 20-year expertise in CTS workforce development. Three integrated objectives guide our training: (i) provide core knowledge through a mentored research project embedded in an academic program; (ii) foster career advancement and enhance professional development; and (iii) enhance scientific agility to overcome translational barriers. The program supports 5 postdoctoral trainees annually (2 PhDs, 3 clinicians) for 1-2 years each. All trainees complete a mentored research project under the guidance of a mentoring team (research mentor(s) and program mentor), supported by an Advisory Committee. Training integrates mentored research, academic coursework, professional development through the ASCEND program, and integration into vibrant scientific communities. Key activities include Research in Progress series, expanded curriculum in implementation science, data science, and learning health system science, a comprehensive mentoring strategy, ASCEND professional development addressing resilience and leadership, integration into Penn's 2,000+ member ITMAT community, access to "Cellicon Valley" industry partnerships, entrepreneurship training, and structured FDA regulatory bootcamp experiences. Upon completion of the program, trainees will be equipped with the tools to become resilient, barrier-breaking scientists. They will thrive in multi-disciplinary research teams, translate discoveries into interventions, and rigorously pursue innovative solutions that are successfully implemented to benefit patients.

Up to $533K
2031-05-31
health research

Free to search & build · $99 one-time to unlock the application pack · No subscription

CTSA Predoctoral T32 at Columbia University

open

NCATS - National Center for Advancing Translational Sciences

For approximately 20 years, the Irving Institute for Clinical and Translational Research (Irving Institute) acting as a NCATS-funded Clinical and Translational Science Award (CTSA) hub, provided training at the predoctoral level, graduating 87 trainees. The overarching goal of the Irving Institute's T32 is to select pre-doctoral trainees from across the broad spectrum of medicine, other health sciences, and basic sciences at Columbia University and prepare them to be leaders of the next generation of clinical and translational investigators. Our T32 has innovative distinguishing features in its disease agnostic approach to recruitment and enrollment of trainees. Because our program will be within our CTSA Program hub, trainees participate in didactic and experiential activities alongside scholars in our K and Master of Science programs. To continue our legacy of training with a central role in advancing models campus-wide, we propose focus on precision translational biomedical health. that leverages the translational scientist characteristics and precision biomedical education for this application. This aligns with and complements NCATS' inclusion of translational science principles in its mission to turn biomedical research discoveries into health solutions. We propose a customized, tailored approach in training and content that supports the mission of developing treatment and interventions for all at the individual and community levels. The T32 includes innovative programming, such as coursework related to career development, n of 1 dense phenotyping to big data analytics, multi-level systems (cells to communities), team science, dissemination and implementation science, and interdisciplinary grant writing; while in parallel developing a deep knowledge of their field developing through their doctoral program. Our goals are founded on our learning research systems and include to: 1) Identify gaps, barriers, and opportunities in training and mentorship that support the T32 trainees and program to foster clinical and translational science and its principles. 2) Develop and refine new components of our training program to provide customized, tailored training and mentorship to enhance the ability of our trainees to engage in scientific inquiry, addressing unmet needs that benefit our patients and communities. 3) To Demonstrate the effectiveness of the T32 program through continuous comprehensive and systematic evaluation and quality improvement. 4) Accelerate Dissemination of our training and mentorship approaches across Columbia, the regional tri-state consortium of CTSA hubs, the national CTSA network, and the field at large. By increasing knowledge of precision translational biomedical health, we will build a workforce that will apply this lens in how they see the world and advance their science—contributing to the mission of our CTSA hub to leverage clinical and translational discoveries to positively impact the health of our patients, communities, and the nation. Our goals align with the NCATS mission to catalyze the next generation of innovative methods and technologies to enhance development, testing, and implementation of diagnostics and therapeutics across various human conditions.

Up to $275K
2031-05-31
health research

Free to search & build · $99 one-time to unlock the application pack · No subscription

CTSA Program at University of Massachusetts

open

NCATS - National Center for Advancing Translational Sciences

PROJECT SUMMARY/ABSTRACT The UMCCTS was funded in 2010 with the vision of building healthier communities together through translational innovation. Our mission is to advance learning and discovery to solve Translational Science challenges and improve well-being by: 1) catalyzing, rigorously testing, and disseminating evidence-driven approaches that remove Translational Science (TS) roadblocks to efficient, high quality, and impactful translational research (TR); and 2) building a workforce of skilled professional staff and investigators capable of changing paradigms in TS and TR. As Massachusetts’ only public university system (UMass) partnered with 3 large clinical systems (UMass Memorial Health; Baystate Health; Lahey Health), we share an enduring focus on public engagement and societal benefit. The UMCCTS engages a broad range of interest holders (communities, patient groups, foundations, industry, NCATS, and CTSA hubs) to ensure that the research we support and workforce we train address problems important to the communities we serve. With our partners, we identify important problems and needs, develop and validate enabling platforms, and provide resources that facilitate transdisciplinary team science. We use data and analytics to generate knowledge, apply that knowledge to improve performance, then use lessons learned to inform and refine the next improvement cycle. UMCCTS workforce development programs ensure the future sustainability of the TS enterprise. Our four Specific Aims correspond to NCATS strategic goals stated in the NCATS NOFO and build on our prior successes: Aim 1: Promote individual and community health by building community-centered systems and approaches that expand and sustain the engagement of participants, communities, and research teams; Aim 2: Develop a robust set of digital tools and informatics systems that engage a broad range of study participants, promote data sharing, enable actionable insights, and that extend our Learning Health System across partners and into home and community settings; Aim 3: Provide resources that overcome TS and operational barriers to continuously improve the quality, efficiency, and impact of TR across the spectrum; Aim 4: Advance the development of a skilled TS workforce through innovative educational curricula, transdisciplinary team-based training, and career development programs. By working with our partners on each of these aims we will accomplish our overarching goal of speeding the development of evidence-based, real-world approaches that promote health, treat disease, and respond to urgent public health needs locally, regionally, and nationally.

Up to $6.0M
2033-01-31
health research

Free to search & build · $99 one-time to unlock the application pack · No subscription

CTSA Research Education R25 at University of California at Davis: Student Physician-Scientist Early Research Experiences (SPHERE) Academy

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NCATS - National Center for Advancing Translational Sciences

PROJECT SUMMARY The primary mission of the UC Davis Clinical and Translational Science Center (CTSC) Research Education Program (R25), titled “Student Physician-Scientist Early Research Experiences (SPHERE),” is to accelerate the development of a workforce to address the nation’s biomedical, behavioral, and clinical research needs by strengthening foundational skills and professional identity in clinical and translational science among first-year medical students aspiring to careers as physician-scientists. The medical and health science communities currently lack efficient and effective strategies for developing a robust physician-scientist workforce. The focus of the SPHERE Academy is first-year medical students, because early, structured exposure to clinical and translational research – prior to completion of a terminal degree – is an underutilized but promising strategy to build a physician-scientist workforce prepared to generate scientific and operational innovations that address barriers along the translational research pipeline. The SPHERE Academy MPIs bring extensive expertise as researchers and medical educators and currently serve as directors of the Academic Research Careers for Medical Doctors (ARC-MD) program at UC Davis, a five-year longitudinal training experience for medical students established in 2019. Building upon the successful ARC-MD program, this R25 incorporates lessons learned and addresses identified challenges. This new CTSC- integrated Academy is distinct from the ARC-MD program in that it (1) expands to include students who are not in ARC-MD and seek a standalone one-year program, (2) adds an oversight structure with three advisory boards, (3) delivers ten weeks of research experiences co-led by 27 faculty with expertise spanning disciplines and stages of the translational science spectrum, (4) includes a community engagement plan, (5) adds a rigorous evaluation component, and (6) develops a novel Physician Translational Scientist Academy toolkit. The SPHERE Academy will utilize UC Davis CTSC resources to cultivate cohorts of medical students equipped to maximize their research development during medical school and promote a more efficient and impactful physician-scientist pipeline. The goals for this R25 are: (1) deliver a two-phase, ten-week research experience that builds clinical and translational science skills and identity among a cohort of student physician-scientists, (2) partner with a community engagement board of the UC Davis CTSC to inform and enhance the research experiences in the SPHERE Academy, and (3) evaluate and disseminate the implementation and impact of the SPHERE Academy. Through its innovative structure, targeted focus, and integration with the CTSC, the SPHERE Academy is positioned to serve as a scalable model for early physician-scientist training across academic medical centers nationwide.

Up to $108K
2031-04-30
health research

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CWRU Postbaccalaureate Research Education Program

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NIGMS - National Institute of General Medical Sciences

PROJECT SUMMARY The current biomedical research workforce does not reflect current US demographics. The National Institutes of Health has established a variety of supportive mechanisms to encourage broad participation in the biomedical workforce. One important NIH initiative is the Post-baccalaureate Research Education Program or PREP. The overall goal of PREP is to develop recent baccalaureate science graduates so that they have the necessary knowledge and skills to pursue PhD or MD/PhD degrees in these fields. Case Western Reserve University (CWRU) was awarded PREP funding beginning in 2007. The program, known as CasePREP, has been notably successful, matriculating 82 Scholars into PhD or MD/PhD programs across the nation. The majority (85%) of these Scholars have completed their graduate degrees or are actively training, evidence of CasePREP’s effectiveness and experience in preparing Scholars for careers in science. This new proposal seeks to re-start this program by funding six CasePREP Scholars each year for five years. The key components of a resumed CasePREP will involve individually tailored graduate coursework, professional credentials enhancement, well- crafted experiential skill development, immersion in the PhD student experience, and extensive exposure to biomedical research. CasePREP Scholars will complete a one-year apprenticeship in CWRU School of Medicine faculty laboratories and computational research groups located throughout many of the CWRU 14 PhD-granting programs. Proposed PREP mentor laboratories and computational research groups are well funded, dynamic, and led by trained mentors with substantial experience with trainees from a variety of backgrounds in science. In addition, CasePREP Scholars will complete graduate level coursework, professional skills development, and other enrichment activities. These core developmental experiences are designed to further strengthen a student’s scholarly potential and improve their research skills, ultimately leading to their matriculation into and completion of rigorous biomedical doctoral degree programs across the nation. Important outcome assessments will show improved graduate school application credentials, enhanced research and presentation skills, improved attitudes about research careers, and greater than 75% success rates in PREP Scholar matriculation into PhD programs and completion of the PhD degree, respectively. Scholars will also have improved knowledge of the tools and resources needed to achieve and maintain resiliency as a scientist. A main overall outcome for CasePREP is broadening representation in the biomedical PhD programs at CWRU and across the nation.

Up to $503K
2031-04-30
health research

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CyberAICorps Scholarship for Service

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U.S. National Science Foundation

Cyberspace has transformed the daily lives of people. Society's overwhelming reliance on cyberspace, however, has exposed the system's fragility and vulnerabilities: corporations, agencies, national infrastructure, and individuals continue to suffer cyber-attacks. Achieving a truly secure cyberspace requires addressing both challenging scientific and engineering problems involving many components of a system, and vulnerabilities that stem from human behaviors and choices. Examining the fundamentals of security and privacy as a multidisciplinary subject can lead to fundamentally new ways to design, build, and operate cyber systems, protect existing infrastructure, and motivate individuals to learn about cybersecurity. The Cybersecurity Enhancement Act of 2014, as amended by the National Defense Authorization Acts for 2018 and 2021, and the CHIPS and Science Act of 2022, authorizes the National Science Foundation (NSF), in coordination with the Office of Personnel Management (OPM) and the Department of Homeland Security (DHS), to offer a scholarship program to recruit and train the next generation of cybersecurity professionals to meet the needs of the cybersecurity mission of federal, state, local, and tribal governments. The goals of the CyberCorps Scholarship for Service (SFS) program are aligned with the U.S. strategy to develop a superior cybersecurity workforce. The program goals are to: (1) increase the number of qualified and diverse cybersecurity candidates for government cybersecurity positions; (2) improve the national capacity for the education of cybersecurity professionals and research and development workforce; (3) hire, monitor, and retain high-quality CyberCorps graduates in the cybersecurity mission of the Federal Government; and (4) strengthen partnerships between institutions of higher education and federal, state, local, and tribal governments. While all three agencies work together on all four goals, NSF s strength is in the first two goals; OPM s in goal (3); and DHS in goal (4). The SFS Program welcomes proposals to establish or to continue scholarship programs in cybersecurity. A proposing institution must provide clearly documented evidence of a strong existing academic program in cybersecurity. In addition to information provided in the proposal narrative, such evidence can include ABET accreditation in cybersecurity; a designation by the National Security Agency and the Department of Homeland Security as a Center of Academic Excellence in Cyber Defense Education(CAE-CDE), in Cyber Operations (CAE-CO) or in Research (CAE-R); or equivalent evidence documenting a strong program in cybersecurity. Service Obligation: All scholarship recipients must work after graduation in the cybersecurity mission of a federal, state, local, or tribal government organization, or certain other qualifying entities, for a period equal to at least the length of the scholarship. The SFS Program also supports efforts leading to an increase in the ability of the United States higher education enterprise to produce cybersecurity professionals. Funding opportunities in this area are provided via the Secure and Trustworthy Cyberspace - Education Designation (SaTC-EDU) and other programs (see the section "Increasing National Capacity in Cybersecurity Education" for more details.)

$2M – $5M
rolling
sciencetechnology

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Cyberinfrastructure Training, Education, Advancement, and Mentoring for Our 21st Century Workforce (CI-TEAM)

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U.S. National Science Foundation

New information, communication, and computational technologies have had profound impacts on the practice of science and engineering. Linked to create a comprehensive cyberinfrastructure, the systems, tools, and services emerging from these new technologies are enabling individuals, groups, and organizations to advance research and education in ways that revolutionize who can participate, what they can do, and how they do it. Sustaining this revolution across all areas of science and engineering requires the formation of a workforce with the knowledge and skills needed to design and deploy as well as adopt and apply these cyber-based systems, tools and services over the long-term. The opportunity for such preparation should be available at all stages of formal and informal education, training and professional development, and must be extended to all interested individuals and communities.The CI-TEAM program supports projects that position the national science and engineering community to engage in integrated research and education activities promoting, leveraging and utilizing cyberinfrastructure systems, tools and services.CI-TEAM awards will:* Prepare current and future generations of scientists, engineers, and educators to design and develop as well as adopt and deploy, cyber-based tools and environments for research and learning, both formal and informal.* Expand and enhance participation in cyberinfrastructure science and engineering activities of diverse groups of people and organizations, with particular emphasis on the inclusion of traditionally underrepresented individuals, institutions especially Historically Black Colleges and Universities (HBCUs) and Minority Serving Institutions (MSIs), and communities as both creators and users of cyberinfrastructure.This solicitation seeks three types of project proposals, all aimed at the preparation of a diverse, cyberinfrastructure-savvy science and engineering workforce. One type of proposal, the Demonstration Project, is exploratory in nature and may be somewhat limited in scope and scale. Demonstration Projects have the potential to serve as exemplars to effective larger-scale implementation and diffusion activities in the future. The second project type, the Implementation Project, is generally larger in scope or scale and draws on prior experience with the activities or the teams proposed. The third project type, the Diffusion Project, is expected to engage broad national audiences with research results, resources, models, and/or technologies. Implementation or Diffusion Projects are expected to deliver sustainable learning and workforce development activities that complement ongoing NSF investment in cyberinfrastructure.All CI-TEAM projects seek to broaden and diversify the population of individuals and institutions participating in cyberinfrastructure activities specifically and, thereby, science and engineering more generally. Toward that goal, the three types of projects consist of collaborations with expertise in multiple disciplines and involve partnerships that support integrated research and learning among diverse organizations including, as appropriate, academic institutions of higher learning, primary and secondary schools, government, industry, professional societies, other not-for-profit organizations, and international partners. Other key features of CI-TEAM projects involve a commitment to: leveraging existing or current development efforts in cyberinfrastructure technologies; open software standards and open educational resources; the integration of research and learning; institutional partnerships; and strategic implementation, management, and evaluation plans. Following merit review of the proposals received, NSF expects to select for support 6 to 7 Demonstration Projects at up to $250,000 total each and 3 to 6 Implementation or Diffusion Projects at up to $1,000,000 total each that together constitute a rich portfolio of cyberinfrastructure-related workforce development activities.

$250K – $1M
rolling
sciencetechnology

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DE-FOA-0002231: Notice of Intent to Issue Funding Opportunity Announcement No. DE-FOA-0002229

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Golden Field Office

The Office of Energy Efficiency and Renewable Energy (EERE) intends to issue, on behalf of the Fuel Cell Technologies Office, a Funding Opportunity Announcement (FOA) entitled H2@Scale New Markets FOA , to advance innovations that will build new markets for H2@Scale. Transformational R&amp;D and innovative concepts for new H2@Scale markets will be key to expanding hydrogen opportunities and converting them into market solutions that benefit the American people and provide added value for the economy. Potential topics under the FOA include: Electrolyzer Manufacturing R&amp;D Advanced Carbon Fiber for Compressed Storage Tanks Fuel Cell R&amp;D for Heavy-Duty Applications H2@Scale New Markets R&amp;D HySteel H2@Scale New Markets Demonstrations Training and Workforce Development This FOA supports the vision of affordable and large-scale production, storage, transport, and utilization of hydrogen in the United States. This notice of intent (NOI) is issued so that interested parties are aware of the EERE s intention to issue this FOA in the near term. All of the information contained in this NOI is subject to change. EERE will not respond to questions concerning this NOI. Once the FOA has been released, EERE will provide an avenue for potential applicants to submit questions. EERE plans to issue the FOA in January of 2020 via the EERE Exchange website https://eere-exchange.energy.gov/. If applicants wish to receive official notifications and information from EERE regarding this FOA, they should register in EERE Exchange. When the FOA is released, applications will be accepted only through EERE Exchange.

$1 – $2
rolling
energyclean energy

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Digital Equity Competitive Grant Program

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National Telecommunications and Information Admini

This Notice of Funding Opportunity solicits applications for the Digital Equity Competitive Grant Program ( Competitive Grant Program or Program ), the third of three digital equity programs authorized by the Infrastructure Investment and Jobs Act of 2021, Division F, Title III, Public Law 117-58, 135 Stat. 429, 1209 (November 15, 2021) ( Infrastructure Act, also known as the Digital Equity Act or DE Act ). The Competitive Grant Program will make funds available to a wide range of entities to address barriers to digital equity faced by Covered Populations as defined by 47 U.S.C. 1721(8). The Competitive Grant Program will support efforts to achieve digital equity, promote digital inclusion activities, and spur greater adoption and meaningful use of broadband among the Covered Populations. Specifically, the Digital Equity Act authorizes funds to be used for the development and implementation of digital inclusion activities that benefit the Covered Populations; programs that facilitate the adoption of broadband by Covered Populations to provide educational and employment opportunities; training programs that cover basic, advanced, and applied skills; workforce development programs; access to equipment, instrumentation, networking capability, hardware and software, or digital network technology for broadband services at low or no cost; and the construction or operation of public access computing centers for Covered Populations. Awards will focus on addressing the needs of the Covered Populations not met by the Digital Equity Capacity Grant Program and will strive for a diverse pool of recipients. To ensure funds are directed to the most effective programs with the greatest reach, and to minimize administrative overhead, NTIA encourages proposals that demonstrate a broad partnership of entities with the ability to administer significant resources and address the varied concerns of the Covered Populations.

rolling
sciencetechnology

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Discovery of circulating RNA biomarkers for pancreatic cancer detection and monitoring

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NIH

Significance to VA: Pancreatic cancer affects nearly 1,000 Veterans annually, and most patients are diagnosed with advanced stage disease that is rapidly fatal. Early detection greatly improves the chances of long-term survival, but no effective screening methods currently exist. A non-invasive blood test (liquid biopsy) for pancreatic cancer could enable early detection, but past efforts have failed to outperform standard of care imaging. Plasma circulating cell-free RNA (cfRNA) shows tremendous potential as a liquid biopsy analyte, yet its disease specificity remains unclear, and technical challenges have impeded its clinical translation. Our novel cfRNA sequencing protocol, validated in pilot studies, supports our hypothesis that tumor tissue- derived cfRNAs can be utilized for cancer detection and monitoring. Innovation and Impact: Our methodology overcomes several technical barriers, indicating that cfRNA profiling can be highly sensitive and reproducible. The project will use high-resolution spatial transcriptomics technology to map cfRNAs to specific tumor cells and determine whether cfRNA profiling can infer disease features without a tissue biopsy. Early detection of pancreatic cancer would enable patients to undergo potentially curative surgery, return to the workforce, and maintain their quality of life. If this project is successful, our cfRNA approach could be rapidly applied to other cancer types that lack effective screening or monitoring. Specific Aims: Aim 1) Map RNA expression from pancreatic tumor tissue to the bloodstream. We hypothesize that distinct cfRNAs are directly produced from pancreatic tumor tissues and can be used for disease inference. The objective is to identify whether cfRNAs can predict disease characteristics and obviate the need for tissue biopsies. Aim 2) Identify circulating RNAs for pancreatic cancer detection and monitoring. We hypothesize that cfRNAs can be used for disease detection and estimation of disease burden in patients with established cancer. The objective is to determine whether cfRNA profiling is non-inferior to cross-sectional imaging and tumor markers for patients with established disease. Methodology: Aim 1 is a retrospective cohort study of Veterans (N=40) that will evaluate matched tissue and blood specimens using high-resolution spatial transcriptomics and plasma cell-free RNA sequencing. Aim 2 is a prospective case-control study of Veterans (N=225) with pancreatic cancer, benign conditions, and other cancers that will collect clinical information and blood specimens for molecular profiling over a 2-year period. Computational modeling of molecular profiling data will leverage modern AI/machine learning (ML) methods. Path to Translation/Implementation: The next step would be a clinical trial of cfRNA diagnostics in patients who are at high risk for developing pancreatic cancer, including patients with hereditary cancer mutations and/or a strong family history of pancreatic cancer. Training: The PI aspires to lead a translational research lab that pioneers molecular diagnostics to improve cancer care. This project incorporates training in spatial transcriptomics, AI/ML, and clinical biomarker development, coupled with mentorship toward research independence.

2031-03-31
health research

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