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Department of Labor

AWARD PURPOSE STRIVE GAINING REAL OPPORTUNITIES IN THE WORKFORCE (GROW) - STRIVE GROW WILL IMPROVE EMPLOYMENT OUTCOMES FOR 414 YOUNG ADULTS BY PROVIDING THE FOUNDATIONAL, OCCUPATIONAL AND LEADERSHIP TRAINING, MENTORING, EDUCATION, CASE MANAGEMENT, AND SERVICES AND SUPPORTS THEY NEED TO ENTER THE WORKFORCE OR RETURN TO EDUCATION. ACTIVITIES PERFORMED STRIVE GROW IS AN INNOVATIVE, COMPREHENSIVE YOUNG ADULT REENTRY PROGRAM THAT WILL IMPROVE EMPLOYMENT OUTCOMES FOR 414 YOUTH BY PROVIDING—IN PARTNERSHIP WITH VIOLENCE PREVENTION PROVIDERS, EMPLOYERS, AND THE JUSTICE SYSTEM—OCCUPATIONAL TRAINING, EDUCATION, CASE MANAGEMENT, MENTORING, AND THE SERVICES AND SUPPORTS THEY NEED TO ENTER AND REMAIN IN THE WORKFORCE. STRIVE GROW WILL SERVE JUSTICE-INVOLVED YOUNG ADULTS AND YOUNG ADULTS IMPACTED BY COMMUNITY VIOLENCE, PREPARING THEM TO MEET THE NEEDS OF THEIR LOCAL LABOR MARKETS WITH THE SKILLS REQUIRED BY EMPLOYERS. STRIVE IS COMMITTED TO A POSITIVE YOUTH DEVELOPMENT FRAMEWORK, INCLUDING MENTORING AND LEADERSHIP DEVELOPMENT TO SUPPORT THE NECESSARY MOTIVATION AND DISCIPLINE REQUIRED FOR THE ACHIEVEMENT OF LONG-TERM GOALS. STRIVE RECOGNIZES THE IMPORTANCE OF TRAUMA-INFORMED CARE AND INCORPORATES IT INTO ALL ITS PROGRAMS. STRIVE'S COHORT APPROACH FOSTERS SUSTAINED CONNECTIONS AND ENGAGEMENT IN COMMUNITY BUILDING ACTIVITIES WITH POSITIVE PEER GROUPS. STRIVE WILL WORK WITH CREDIBLE MESSENGER MENTORING MOVEMENT TO TRAIN STAFF, IDENTIFY CREDIBLE MESSENGERS, AND SUPPORT THE VIOLENCE PREVENTION PARTNER'S PROGRAMMING. SINCE PARTICIPANTS MEET AND INTERACT WITH SEVERAL STAFF, MANY OF WHOM HAVE LIVED EXPERIENCE OF INCARCERATION OR COMMUNITY VIOLENCE, STRIVE ENSURES THAT CREDIBLE MESSENGERS REACH ALL PARTICIPANTS. COLLABORATION BETWEEN STRIVE, SUBGRANTEES, AND LOCAL SERVICE PROVIDER PARTNERS MEANS STAFF SHARE INFORMATION AND BEST TECHNIQUES FOR ENGAGING AND SERVING YOUNG ADULTS. PARTNERSHIPS BETWEEN SUB-GRANTEES AND EMPLOYERS WILL ENSURE ALL PARTICIPANTS HAVE A POST-PROGRAM PLACEMENT; POST-PLACEMENT FOLLOW-UP SUPPORTS THE PROGRAM'S SUSTAINED IMPACT. DELIVERABLES AT LEAST 60% OF PARTICIPANTS WHO ENTER OCCUPATIONAL SKILLS STRAINING OR EDUCATION WILL ATTAIN A CREDENTIAL; 70% OF PARTICIPANTS WHO ENTER OCCUPATIONAL SKILLS TRAINING OR EDUCATION WILL DEMONSTRATE MEASURABLE SKILLS GAINS; AT LEAST 70% OF PARTICIPANTS WHO ARE PLACED IN A JOB WILL STILL BE EMPLOYED THE SECOND QUARTER AFTER EXIT; AT LEAST 60% WILL BE EMPLOYED THE FOURTH QUARTER AFTER EXIT. MEDIAN EARNINGS WILL BE $5750. NO MORE THAN 5% OF PARTICIPANTS WILL BE ARRESTED FOR VIOLENT CRIMES COMMITTED AFTER PROGRAM ENTRY; THE PROGRAM WILL LIMIT RECIDIVISM TO NO MORE THAN 10% OF PARTICIPANTS. INTENDED BENEFICIARY JUSTICE- AND VIOLENCE-IMPACTED YOUNG ADULTS, THEIR FAMILIES, AND RESIDENTS OF THE HIGH-POVERTY, HIGH-CRIME TARGET AREAS IN ATLANTA, BRIDGEPORT, AND CHICAGO. SUBRECIPIENT ACTIVITIES ALL SUBGRANTEES WILL IMPLEMENT THE PROGRAM MODEL, COORDINATE PROGRAM OPERATIONS WITH THE VIOLENCE PREVENTION AND JUSTICE SYSTEM PARTNERS AND ENSURE THAT THE PARTNERS WILL SUPPORT AND DELIVER PROGRAM COMPONENTS AND COLLABORATE WITH OTHER PARTNERS AS INDICATED IN THE GRANT PROPOSAL. SUBGRANTEES WILL FURTHER ENSURE THAT EDUCATION AND OCCUPATIONAL TRAINING PROVIDED ARE IN LOCALLY IN-DEMAND INDUSTRIES BY MAINTAINING REGULAR CONTACT WITH EMPLOYER PARTNERS AND IN CONSULTATION WITH STATE OR LOCAL WORKFORCE DEVELOPMENT BOARDS; PARTICIPATE IN A DOL EVALUATION IF UNDERTAKEN AS SPECIFIED IN FOA-ETA-22-03; SUBMIT REGULAR AND TIMELY REPORTS AND UPDATES, INCLUDING ALL REQUIRED PERFORMANCE MANAGEMENT DATA AND FISCAL DOCUMENTS, TO STRIVE TO ASSIST IN GRANT MANAGEMENT AND SUCCESSFUL PROGRAM EXECUTION AND ADHERE TO ALL APPLICABLE FEDERAL REQUIREMENTS; USE ALL PERFORMANCE MANAGEMENT TOOLS AS MANDATED BY THE PROPOSAL; AND PROVIDE SERVICES TARGETED TO PARTICIPANTS IN THE HIGH-POVERTY, HIGH-CRIME TARGET AREA(S) AS IDENTIFIED IN THE PROPOSAL.

Department of Labor

AWARD PURPOSE THE PURPOSE OF BOOST GO IS TO PREPARE YOUNG ADULTS FOR EMPLOYMENT THROUGH EDUCATION AND TRAINING, PAID WORK EXPERIENCES, MENTORSHIP, AND LEADERSHIP DEVELOPMENT WITH DELIVERY OF EVIDENCE-BASED PRACTICES INTERVENTIONS. ACTIVITIES PERFORMED BOOST GO WILL SUPPORT JUSTICE INVOLVED YOUNG ADULTS FOR EMPLOYMENT AND VIOLENCE PREVENTION BY 1. HELPING YOUNG ADULTS TO INCREASE THEIR CONFLICT RESOLUTION SKILLS AND DEVELOP STRATEGIES TO PREVENT AND AVOID VIOLENCE. THIS WILL BE ACHIEVED IN PARTNERSHIP WITH SKY RANCH BEHAVIORAL SERVICES TO PROVIDE VIOLENCE PREVENTION, MENTORING, AND LEADERSHIP DEVELOPMENT THROUGH DELIVERY OF EVIDENCE-BASED INTERVENTIONS OF AGGRESSION REPLACEMENT TRAINING® ART) AND MENTORS IN VIOLENCE PREVENTION (MVP) CURRICULUM DESIGNED BY UNIVERSITY OF NORTHERN IOWA CENTER FOR VIOLENCE PREVENTION (CVP). PARTNERS WILL COLLABORATE TO RECRUIT AND TRAIN MULTICULTURAL MENTORS WITH LIVED EXPERIENCE. 2. PREPARING YOUNG ADULTS FOR THE WORLD OF WORK BY HELPING YOUNG ADULTS IDENTIFY CAREER INTERESTS, ATTAIN RELEVANT SKILLS, AND GAIN WORK EXPERIENCE. BOOST GO WILL ENSURE PARTICIPANTS RECEIVE COMPREHENSIVE EMPLOYMENT AND CAREER SERVICES UTILIZING STEP ON UP® CAREER READINESS AND GROWTH FOCUSED CASE MANAGEMENT (GFCM), RESULTING IN A CUSTOMIZED INDIVIDUAL DEVELOPMENT PLAN (IDP). PARTICIPANTS WILL GAIN WORK EXPERIENCE IN EMPLOYMENT, APPRENTICESHIP, INTERNSHIP; AND/OR ON-THE-JOB TRAINING WITH HIGH PRIORITY EMPLOYER PARTNERS HIGH DEMAND CAREERS, BASED ON CURRENT LABOR MARKET INFORMATION (LMI) AND IOWA WORKFORCE DEVELOPMENT TO INCLUDE CHILDCARE, CONSTRUCTION, FOOD/MEAT PROCESSING, HEALTH CARE, MAINTENANCE/ SAFETY, COMMERCIAL TRUCKING, WAREHOUSE LOGISTICS/OPERATIONS, AND WELDING. WRAPAROUND SERVICES TO ADDRESS HOUSING, MENTAL HEALTH, ADDICTION, CHILDCARE, LEGAL SERVICES, WILL BE CUSTOMIZED TO EACH INDIVIDUAL. DELIVERABLES OUTCOMES WILL EXCEED ALL REQUIRED PERFORMANCE OUTCOMES TO INCLUDE A 73% EMPLOYMENT RATE- SECOND QUARTER AFTER EXIT, 65% EMPLOYMENT RATE- FOURTH QUARTER AFTER EXIT, 6,000 MEDIAN EARNINGS, 60% CREDENTIAL ATTAINMENT, 73% MEASURABLE SKILL GAIN, LESS THAN 3% ARRESTS FOR VIOLENT CRIMES, AND LESS THAN AN 8% RECIDIVISM RATE. INTENDED BENEFICIARY BOOST GO WILL REACH AND SERVE 180 YOUNG ADULTS 18-24 YEARS OLD MOST IMPACTED BY POVERTY AND CRIME, WITH PRIORITY ON REACHING MINORITY COMMUNITIES IN THE CENSUS TRACTS. SUBRECIPIENT ACTIVITIES N/A

Department of Labor

AWARD PURPOSE THE PURPOSE OF THIS PROGRAM IS TO INTRODUCE AND PREPARE JUSTICE-INVOLVED YOUTH AND YOUNG ADULTS FOR THE WORLD OF WORK THROUGH PLACEMENT INTO PAID WORK EXPERIENCES, AND ON A PATH TO MORE EQUITABLE CAREER OPPORTUNITIES WITH THEIR PEERS. ACTIVITIES PERFORMED FHI 360'S INTERMEDIARY ROLE WILL SUPPORT THOUGHT LEADERSHIP THROUGH DOCUMENTING STRATEGIES AND OFFERING PEER-TO-PEER LEARNING THROUGH A COMMUNITY OF PRACTICE AND A TOOLKIT OF BEST PRACTICES. WE WILL ALSO BOLSTER THE LOCAL VIOLENCE PREVENTION EFFORTS BY HOSTING TWO VIOLENCE PREVENTION SITUATION TABLE COMMUNITY OF PRACTICE MEETINGS WITH OUR PARTNER OPERATION 2 SAVE LIVES AND WILL CERTIFY FIVE STAFF MEMBERS AS TRAUMA-INFORMED SELF-CARE RESPONSE TRAINERS. THESE TRAINERS WILL THEN TRAIN SUB-GRANTEES AND UP TO 20 EMPLOYERS TO ENHANCE THEIR ABILITY TO HIRE, SUPERVISE, AND MAINTAIN YOUNG ADULTS THAT HAVE EXPERIENCED TRAUMA ASSOCIATED WITH POVERTY, COMMUNITY VIOLENCE, CRIME, AND INCARCERATION. DELIVERABLES 100% ENROLLMENT OF 350 PARTICIPANTS, (WIOA INDICATORS) PARTICIPANTS WILL HAVE 50% CREDENTIAL ATTAINMENT RATE, 70% MEASURABLE SKILL GAINS, MEDIAN EARNINGS OF $5,750 OR MORE 2ND QUARTER AFTER EXIT, 70% EDUCATION AND EMPLOYMENT RATE 2ND QUARTER AFTER EXIT, 60% EDUCATION AND EMPLOYMENT RATE 4TH QUARTER AFTER EXIT, AND (REO-SPECIFIC INDICATORS) LESS THAN 5% ARRESTED FOR A VIOLENT CRIME AND LESS THAN 10% RECIDIVISM. INTENDED BENEFICIARY 350 YOUNG ADULTS BETWEEN THE AGES OF 18-24 WHO ARE IMPACTED BY CRIME, VIOLENCE, AND POVERTY SUBRECIPIENT ACTIVITIES THE GO! PROJECT SUB-GRANTEES WILL USE GROWTH-FOCUSED CASE MANAGEMENT TO GUIDE PARTICIPANTS TOWARDS THEIR GOALS, WHILE THEY ARE GAINING LEADERSHIP SKILLS AND ARE SUPPORTED BY MENTORS. THEIR JUSTICE PARTNERS WILL ASSIST WITH RECRUITMENT AND REFERRALS, VIOLENCE PREVENTION PARTNERS WILL PROVIDE MENTORSHIP AND TRAINING ON CONFLICT RESOLUTION SKILLS, AND EMPLOYER PARTNERS WILL CONTRIBUTE TO THE DESIGN OF OCCUPATIONAL AND JOB-READINESS TRAINING AND HIRE PARTICIPANTS FOR PAID-WORK EXPERIENCES LEADING TO UNSUBSIDIZED EMPLOYMENT. ADDITIONAL PARTNERS SUCH AS WORKFORCE DEVELOPMENT BOARDS WILL SUPPORT CONNECTIONS IN LINE WITH LEADING INDUSTRY TRENDS AND OPPORTUNITIES.

Department of Labor

AWARD PURPOSE TO PREPARE JUSTICE-INVOLVED YOUTH AND YOUNG ADULTS, 18 TO 24 YEARS, FOR THE WORLD OF WORK WITH PAID WORK EXPERIENCES, PROVIDE EDUCATIONAL AND OCCUPATIONAL SKILLED TRAINING IN IN-DEMAND INDUSTRIES SUCH AS CONSTRUCTION, AND HEALTH, AND PROVIDE MENTORSHIP, CONFLICT RESOLUTION, AND LEADERSHIP DEVELOPMENT THAT WILL STRENGTHEN THEIR OPPORTUNITIES FOR EMPLOYMENT AND POST-SECONDARY OPPORTUNITIES. ACTIVITIES PERFORMED THE PROGRAM COMPONENTS ARE OCCUPATIONAL SKILLED TRAINING, PAID WORK EXPERIENCE, EMPLOYMENT AND CAREER SERVICES, LEADERSHIP TRAINING, MENTORSHIP, EDUCATION, SUPPORTIVE SERVICE, AND FOLLOW-UP. OCCUPATIONAL SKILLED TRAINING WILL CONSIST OF ON-SITE CONSTRUCTION TRAINING, CONSTRUCTION THEORY FOR THE OBTAINMENT OF CERTIFICATIONS. THE ON-SITE TRAINING WILL OCCUR AT GJA, AND EMPLOYER PARTNERS WORK SITES. PARTICIPANTS WILL ALSO HAVE AN OPPORTUNITY TO ENROLL IN THE ADVANCED OCCUPATIONAL SKILLED CERTIFICATE PROGRAM AT CCAC. THE CERTIFICATE SKILLED TRAINING AT CCAC IS WELDING, PLUMBING, AND FACILITIES MAINTENANCE TECHNOLOGY. FOR HEALTH, PARTICIPANTS WILL RECEIVE CNA TRAINING FROM CCAC. THE TRAINING IS 24 DAYS WHERE THEY EARN A CNA CERTIFICATION. EMPLOYMENT AND CAREER SERVICES SUCH AS JOB PREPARATION, CAREER EXPLORATION, WORK READINESS, ALLOWS PARTICIPANTS TO EXPLORE CAREER OPPORTUNITIES TO ADDRESS SPECIFIC WORKFORCE CHALLENGES AND BARRIERS FACED BY YOUTH OFFENDERS TO PREPARE THEM FOR JOBS. LEADERSHIP TRAINING WILL BE PROMOTED IN ALL ASPECTS OF THE PROGRAM AND CAPTURES THE UNDERLYING PRINCIPLE THAT PARTICIPANTS ARE OUR FUTURE LEADERS. MENTORSHIP WILL BE PROVIDED; SERVICE OF MENTORS IS THE BACKBONE OF THE PROGRAM TO YOUTH. THEY CAN HELP YOUTH AS THEY GO THROUGH CHALLENGING LIFE TRANSITIONS, INCLUDING DEALING WITH STRESSFUL CHANGES AT HOME, RE-ENTRY FROM THE SYSTEM, OR TO ADULTHOOD. THE STRUCTURE OF THE MENTORSHIP PROGRAM IS ONE YEAR DURATION, ONE-ON-ONE MENTORING, AND SCREENING, TRAINING, AND ON-GOING SUPPORT OF MENTORS. SELECTION OF MENTORS WILL CONSIST OF CARING ADULTS OR INDIVIDUALS WHO HAVE LIVE INCARCERATION AND COMMUNITY VIOLENCE EXPERIENCES. PARTICIPANTS WILL HAVE THE OPPORTUNITY TO RECEIVE HIGH SCHOOL/GED PREPARATION. THEY WILL ALSO RECEIVE POST-SECONDARY EDUCATION INFORMATION FROM CCAC. POSTSECONDARY EDUCATION IS A STRONG FEATURE THROUGHOUT THE PROGRAM SO THAT PARTICIPANTS CAN MASTER SUCCESS WHILE THEY ARE IN COLLEGE. GROWTH FOCUSED CASE MANAGEMENT, SUPPORTIVE SERVICES, FOLLOW-UP, AND RETENTION WILL BE PROVIDED TO HELP YOUTH MASTER SUCCESS IN COMPLETING THE PROGRAM AND MAINTAINING EMPLOYMENT OR ADVANCE TRAINING. DELIVERABLES 70% EDUCATION AND EMPLOYMENT RATE FOR SECOND QUARTER AFTER EXIT; 60% EDUCATION AND EMPLOYMENT RATE FOURTH QUARTER AFTER EXIT; $5,750 MEDIAN EARNINGS SECOND QUARTER AFTER EXIT; 50% CREDENTIAL ATTAINMENT; 70% MEASURABLE SKILL GAINS. INTENDED BENEFICIARY YOUTH, THE COMMUNITIES, PARENTS, SCHOOLS, ETC. SUBRECIPIENT ACTIVITIES N/A

Bank of America Foundation

Supports community development, affordable housing, workforce training, and economic mobility in underserved communities.

NIGMS - National Institute of General Medical Sciences

Abstract Western Washington University (WWU) seeks BRE-SPAD funding to strengthen its research infrastructure and expand faculty and student engagement in biomedical research. As a Predominantly Undergraduate Institution (PUI) with a strong commitment to liberal arts education, WWU has seen steady growth in research activities in the past several years. Research expenditures have almost doubled in less than a decade from $8.5 million in 2014 to $15.9 million in 2023. Yet, WWU’s biological, biomedical, and health sciences R&D expenditures were only $864,000, representing just 5% of total institutional R&D expenditures. WWU will use BRE-SPAD funding to address several institutional challenges, including high teaching loads, lack of key research equipment, limited pre- and post-award administrative support, no central system for recruiting students into undergraduate research opportunities, and a lack of dedicated research development programming. The proposed SPAD initiative at WWU will enhance research capacity through the following specific aims: 1) Improve sponsored programs administration capacity by hiring a new research administrator, training all pre- and post-award staff on NIH proposal submission and award management best practices, and learning from an external evaluation process to improve overall research administration and research development services. 2) Enhance WWU’s research environment by establishing the Viking Biomedical Research Institute (VBR), hiring a program manager, purchasing key biomedical research equipment and supplies, training biomedical faculty in effective NIH research design and proposal writing, incentivizing faculty to develop new course- based undergraduate research experiences (CURES), and creating a centralized mentoring hub for students interested in pursuing biomedical research. and 3) Launch a pilot research project funding program by offering pilot awards, providing faculty release time to focus on research activities, providing resources for undergraduate student participation in the research projects, and enabling faculty to collect data and conduct preliminary analyses that will make subsequent NIH proposals more competitive. By achieving these aims, WWU expects to catalyze a significant increase in the number of faculty – and faculty from a wider range of disciplines – who submit NIH proposals, growth in biomedical research expenditures, increased student participation in biomedical research, an increase in the number of students who graduate with biomedical and health-related degrees and qualifications to enter the regional biomedical workforce, and the establishment of a sustainable and robust biomedical research enterprise.

National Institutes of Health

<p>The purpose of this forecast is to inform the research community that the NIH Common Fund, along with its partner NIH Institutes, Centers, and Offices, is planning to issue a notice of funding opportunity (NOFO) to support the continuation of the&nbsp;<a href="https://commonfund.nih.gov/bridge2ai">Bridge2AI</a> program. Stage 1 of the Bridge2AI program produced unique, large-scale, valuable, and open resource, AI-ready datasets and best practices that the scientific community can adopt. The second stage of the program will foster advances on two fronts: 1) Leverage the AI-ready datasets from Stage 1 to yield products that can address biomedical and behavioral research grand challenges, accelerate the discovery of new biological theories and rules, and advance understanding of biological and behavioral mechanisms of health and disease; 2) Create networks of multidisciplinary researchers to advance the science of AI science by developing necessary metrics and a framework to for trustworthy, reproducible and explainable AI-enabled biomedical and behavioral research.</p><p>This forecast is being provided to allow potential applicants sufficient time to develop meaningful collaborations and responsive projects.</p><p>This NOFO will utilize the U24 activity code.&nbsp;</p><p>The NOFO will support a research initiative that will create a network of multidisciplinary Centers to advance the science of AI science. Centers will work across the evolving landscape of AI science to create a framework for trustworthy, reproducible and explainable AI-enabled biomedical and behavioral research. Center activities will include evaluation of AI models and products built through other initiatives in the program and other sources, convening expert panels and round tables, supporting pilot research activities, multidisciplinary cross-training and dissemination activities to help grow the nascent field of biomedical and behavioral research AI science. The Network of Centers will produce best practices for AI methods and trustworthy AI model building principles, frameworks to enable the evaluation of AI models and methods for reproducibility, replicability and transparency, guiding principles for agentic autonomous labs of the future, and multidisciplinary training to strengthen the American biomedical and behavioral research AI workforce. This initiative will support 3-5 Centers, and is one of twoInitiatives under the Bridge2AI program, the other of which will be supported by a research contract.&nbsp; &nbsp;&nbsp;</p>

National Institutes of Health

The purpose of this forecast is to inform the research community that the NIH Common Fund, along with its partner NIH Institutes, Centers, and Offices, is planning to issue a notice of funding opportunity (NOFO) to support the continuation of the Bridge2AI program. Stage 1 of the Bridge2AI program produced unique, large-scale, valuable, and open resource, AI-ready datasets and best practices that the scientific community can adopt. The second stage of the program will foster advances on two fronts: 1) Leverage the AI-ready datasets from Stage 1 to yield products that can address biomedical and behavioral research grand challenges, accelerate the discovery of new biological theories and rules, and advance understanding of biological and behavioral mechanisms of health and disease; 2) Create networks of multidisciplinary researchers to advance the science of AI science by developing necessary metrics and a framework to for trustworthy, reproducible and explainable AI-enabled biomedical and behavioral research.This forecast is being provided to allow potential applicants sufficient time to develop meaningful collaborations and responsive projects.This NOFO will utilize the U24 activity code. The NOFO will support a research initiative that will create a network of multidisciplinary Centers to advance the science of AI science. Centers will work across the evolving landscape of AI science to create a framework for trustworthy, reproducible and explainable AI-enabled biomedical and behavioral research. Center activities will include evaluation of AI models and products built through other initiatives in the program and other sources, convening expert panels and round tables, supporting pilot research activities, multidisciplinary cross-training and dissemination activities to help grow the nascent field of biomedical and behavioral research AI science. The Network of Centers will produce best practices for AI methods and trustworthy AI model building principles, frameworks to enable the evaluation of AI models and methods for reproducibility, replicability and transparency, guiding principles for agentic autonomous labs of the future, and multidisciplinary training to strengthen the American biomedical and behavioral research AI workforce. This initiative will support 3-5 Centers, and is one of twoInitiatives under the Bridge2AI program, the other of which will be supported by a research contract.

NINDS - National Institute of Neurological Disorders and Stroke

ABSTRACT Activity-dependent variation in synaptic AMPA receptor (AMPAR) content, referred to as ‘synaptic plasticity’, is a mechanism whereby information is stored in neural networks that give rise to higher order cognitive skills such as learning and memory. During long-term potentiation (LTP), a widely studied form of synaptic plasticity, extrasynaptic AMPARs are recruited from nearby reserve pools, including perisynaptic regions on the cell surface and intracellular compartments, and subsequent anchored with the postsynaptic density (PSD). AMPARs are associated with a diverse suite of transmembrane auxiliary proteins that regulate trafficking and biophysical properties. A large body of evidence spanning decades of investigation has established mechanisms by which AMPARs are anchored within the PSD. In contrast, the molecular mechanisms that maintain AMPARs as reserve pools of extrasynaptic receptors are largely unknown. Given that recruitment of reserve pools of extrasynaptic AMPARs underlies the rapid strengthening of synapses that occurs during LTP, the molecular mechanisms that establish such reserve pools are critical to our understanding of synaptic plasticity and represent a major gap in our knowledge. In the hippocampus, the predominant AMPAR auxiliary factors are transmembrane AMPA receptor regulatory protein gamma 8 (TARP8), cornichon-2 (CNIH-2), and synapse differentiation induced gene 4 (SynDIG4; SD4), also known as Prrt1 (Proline-rich transmembrane protein 1). Previously, we found that extrasynaptic GluA1-AMPAR reserve pools are reduced in SD4 knockout (KO) hippocampal neurons compared to wild-type (WT). SD4 preferentially associates with affinity-purified GluA1-AMPARs over AMPAR complexes without GluA1. Furthermore, acute hippocampal slices from SD4 KO mice do not undergo GluA1-dependent tetanus- induced LTP, while GluA1-independent theta-burst stimulation LTP (TBS-LTP) remains unimpaired. Analyses of native hippocampal GluA1-AMPARs showed that SD4 is positioned at the interface of GluA1 and CNIH-2, consistent with SD4’s putative role in GluA1-AMPAR trafficking and localization. We hypothesize that SD4 establishes reserve pools of GluA1-AMPARs at perisynaptic sites that are targeted to synapses during LTP. In this application we propose a comprehensive multidisciplinary approach to investigate SD4-dependent regulation of GluA1-containing AMPARs with molecular, cellular, and electrophysiological methods. In Aim 1 we test the prediction that SD4 interaction with GluA1-AMPARs is required for synaptic plasticity. In Aim 2 we test the prediction that SD4 promotes TARP8-dependent synaptic targeting of GluA1-AMPARs during LTP. Completion of these studies will address a major gap in our understanding of the mechanisms by which AMPAR complexes are maintained in reserve pools outside of the PSD in hippocampal neurons and address the role played by SD4 in synaptic targeting of GluA1-AMPARs during plasticity. Through these studies to understand mechanisms by which AMPAR complexes are maintained in reserve pools for plasticity, we will simultaneously diversify the neuroscience workforce by training and mentoring individuals from diverse backgrounds in the proposed research project (Aim 3). We hypothesize that SD4 establishes reserve pools of GluA1-AMPARs at perisynaptic sites that are targeted to synapses during LTP. We further hypothesize that by providing structured mentoring and training for undergraduate students from marginalized backgrounds in the proposed research, we expect to broaden participation, promote retention, and diversity the neuroscience workforce. The experiments and activities proposed in the three aims test predictions of these hypotheses.

U.S. National Science Foundation

The Broadening Participation in Engineering (BPE) Program is a Directorate-wide activity to support the development of a diverse and well-prepared workforce of engineering graduates, particularly those with advanced degrees. A central theme of the program's activities is enhancing the ability of early career faculty members, particularly those from underrepresented groups, to succeed in their careers as researchers and educators. The Broadening Participation in Engineering Program supports projects to engage and develop diverse teams that can offer unique perspectives and insights to challenges in engineering research and education. By seeing problems in different ways, a diverse workforce can encourage innovation and scientific breakthroughs. Throughout this Program Description, the term underrepresented groups will refer to and include the following: women, persons with disabilities, and ethnic/racial groups which are in the minority in engineering, specifically African Americans, Hispanics, Native Americans, Alaska Natives, and Pacific Islanders. The Engineering Directorate recognizes that broadening participation is a systemic issue, with a need for wide-ranging and comprehensive interventions at all levels of the educational system. While there is a general need to diversify pathways that lead to engineering careers, the BPE program currently supports engineering faculty, particularly early career faculty, in integrating broadening participation and diversity with their scholarly activities, including education, research and innovation. Given that engineering addresses human needs, the US population is becoming much more diverse, and engineering practice increasingly turns to customers in designing innovations, it is critical that the faculty of the future are able to draw from diverse perspectives in their engineering research and educational activities.In alignment with the goals of the Engineering Directorate (ENG) and with other programs in the Engineering Education and Centers Division, the BPE Program is interested in areas related to:Understanding how a diverse engineering student body, professional workforce, and faculty impact engineering innovation and productivity.The underlying issues affecting the differential participation rates in engineering, particularly those that can be addressed by engineering faculty members. The experiences and interactions that enhance or inhibit underrepresented groups' persistence to degree and career interest in the professoriate.BPE award activities should be informed by the body of knowledge that surrounds these (and other) important research questions; and in turn add to that knowledge base. The Broadening Participation in Engineering program has three synergistic elements: Broadening Participation Research Initiation Grants in Engineering (BRIGE) is designed to promote the development of early career faculty who will become champions for diversity and broadening participation throughout their careers, and who can serve as change agents on their campuses. BRIGE awards will enable early career faculty to integrate effective diversity strategies in their engineering research, education, and innovation activities, thus making them more competitive for promotion and tenure or receiving additional NSF funding such as CAREER awards. Proposals from women, persons with disabilities, and members of groups underrepresented in engineering as well as faculty from Minority Serving Institutions are especially encouraged. BRIGE proposals may only be submitted through the BRIGE solicitation.Establishing Mentoring and Networking Opportunities for early career engineering faculty members that allow targeted faculty to engage with, learn from, and network with diverse individuals and groups in ways that will demonstrably enhance their long term career success. The program is particularly interested in creating opportunities for early career faculty from groups typically under-represented in engineering departments. Funds will be utilized primarily to seed new networking and mentoring opportunities rather than fund ongoing efforts; thus all projects are expected to develop a plan for sustainability independent of further NSF support. Broadening Participation Research supports up to 3-year research projects that seek to create and study new models and innovations related to the participation and success of groups underrepresented in engineering graduate education, postdoctoral training, and academic engineering careers. The program accepts a range of project scales from small, exploratory projects to larger scale investigations with a broad, systemic scope; project budgets should match the project scope. Small-scale, exploratory projects that contribute to the knowledge base of diversifying faculty in engineering-for example exploring matriculation into graduate programs, reward structures for faculty, or ways to broaden participation from specific groups-are strongly encouraged.

New York Power Authority (NYPA)

As part of NYPA's funding of its workforce training incentives is the renewable energy field, NYPA is supporting the Bronx Economic Development Corporation. The funds will support a pilot program aimed to equip Bronx-based college students with the exposure and training necessary to take advantage of opportunities in the clean energy industry.

U.S. National Science Foundation

Build and Broaden (B2) supports fundamental research and research capacity across disciplines at minority-serving institutions (MSIs) and encourages research collaborations with scholars at MSIs. Growing the science, technology, engineering and mathematics (STEM) workforce is a national priority. National forecasts of the impending shortage of workers with science and engineering skills and essential research workers underscore a need to expand opportunities to participate in STEM research (President's Council of Advisors on Science and Technology, 2012). MSIs make considerable contributions to educating and training science leaders for U.S. economic growth and competitiveness. Yet NSF has received comparatively few grant submissions from, or involving, scholars at MSIs. Targeted outreach activities reveal that MSIs have varying degrees of familiarity with funding opportunities within NSF and particularly within the Social, Behavioral and Economic (SBE) Sciences Directorate. As a result, NSF is limited in its ability to support research and training opportunities in the SBE sciences at these institutions. With its emphasis on broadening participation , Build and Broaden is designed to address this problem. SBE offers Build and Broaden in order to increase proposal submissions, advance research collaborations and networks involving MSI scholars, and support research activities in the SBE sciences at MSIs. Proposals that outline research projects in the SBE sciences that increase students' pursuit of graduate training, enhance PI productivity build research capacity, or cultivate partnerships are especially encouraged to apply. Proposals are invited from single principal investigators based at MSIs and from multiple co-investigators from groups of MSIs. Principal investigators who are not affiliated with MSIs may submit proposals, but must collaborate with PIs, co-PIs, or senior personnel from MSIs and describe how their project will foster research partnerships or capacity-building with at least one MSI as a primary goal of the proposed work. Proposals may address any scientific and cross-disciplinary areas supported by SBE. These areas include anthropology, archaeology, cognitive neuroscience, decision science, ecological research, economics, geography, linguistics, law and science, organizational behavior, political science, public policy, security and preparedness, psychology, and sociology. To find research areas supported by SBE please visit the SBE programs page or visit the NSF funding and awards page.

NIAID - National Institute of Allergy and Infectious Diseases

Abstract Despite decades of efforts to increase representation in American higher education, racial equity in full-time faculty positions for underrepresented minority (URM) groups remains an unrealized goal. Greater representation of Black scholars in American academia and other research positions is needed to foster innovative solutions to cross-disciplinary racial health equity issues. To help address this underrepresentation and to increase diversity in the scientific research workforce, we propose to leverage our team’s health equity- focused research portfolio to provide research training combined with community-based experiential learning opportunities for URM undergraduate students through the Building Research and Implementation capacity for Driving Growth and Equity (BRIDGE) Collaborative Training Program at George Washington University (GWU). BRIDGE trainees will receive six weeks of paid summer residential training and a year-long virtual participatory learning program, culminating in at least one academic publication. The residential program will be hosted at GWU and will provide BRIDGE trainees the opportunity to engage in collaborative research efforts, to meet and network with researchers, clinicians, and community-based organization leaders, and to kickstart their research careers through the training needed to produce original health equity research. Our Specific Aims are: Aim 1: Identify and recruit URM trainees for the BRIDGE Collaborative Training program. We will recruit a total of 8 trainees each summer from 4 participating institutions per year to participate in the BRIDGE collaborative. Aim 2: Implement an HIV implementation science and equity training curriculum, residential research training program combined with community-based experiential learning opportunities in Washington, DC. Aim 3: Form and sustain virtual learning communities that will meet before and after the residential session, provide peer support and guidance among students and receive mentorship from a BRIDGE Collaborative Training program.

California Employment Training Panel

California Employment Training Panel administers workforce development grants funding job training, apprenticeships, incumbent worker training, and employer-based training programs in CA.

National Institutes of Health

The NIH Research Education Program (R25) supports research education activities in the mission areas of the NIH. The over-arching goal of this NCI R25 program is to support educational activities that complement and/or enhance the training of a workforce to meet the nations biomedical, behavioral and clinical research needs. To accomplish the stated over-arching goal, this Notice of Funding Opportunity (NOFO) will support creative educational activities with a primary focus on Courses for Skills Development. Applications are encouraged that propose innovative, state-of-the-art programs that address the cause, diagnosis, prevention, or treatment of cancer, rehabilitation from cancer, or the continuing care of cancer patients and the families of cancer patients.

National Institutes of Health

The NIH Research Education Program (R25) supports research education activities in the mission areas of the NIH. The over-arching goal of this NCI R25 program is to support educational activities that complement and/or enhance the training of a workforce to meet the nations biomedical, behavioral and clinical research needs. To accomplish the stated over-arching goal, this Notice of Funding Opportunity (NOFO) will support creative educational activities with a primary focus on Curriculum or Methods Development. Applications are encouraged that propose innovative, state-of-the-art programs that address the cause, diagnosis, prevention, or treatment of cancer, rehabilitation from cancer, or the continuing care of cancer patients and the families of cancer patients.

National Institutes of Health

The NIH Research Education Program (R25) supports research education activities in the mission areas of the NIH. The over-arching goal of this NCI R25 program is to support educational activities that complement and/or enhance the training of a workforce to meet the nations biomedical, behavioral and clinical research needs. To accomplish the stated over-arching goal, this Notice of Funding Opportunity (NOFO) will support creative educational activities with a primary focus on Curriculum or Methods Development. Applications are encouraged that propose innovative, state-of-the-art programs that address the cause, diagnosis, prevention, or treatment of cancer, rehabilitation from cancer, or the continuing care of cancer patients and the families of cancer patients.

National Institutes of Health

The NIH Research Education Program (R25) supports research education activities in the mission areas of the NIH. The over-arching goal of this NCI R25 program is to support educational activities that complement and/or enhance the training of a workforce to meet the nations biomedical, behavioral and clinical research needs. To accomplish the stated over-arching goal, this Notice of Funding Opportunity (NOFO) will support creative educational activities with a primary focus on Research Experiences. Applications are encouraged that propose innovative, state-of-the-art programs that address the cause, diagnosis, prevention, or treatment of cancer, rehabilitation from cancer, or the continuing care of cancer patients and the families of cancer patients.

Department of Health

To address statewide workforce shortages, the CPT program will fund education and participant support services to provide holistic educational and professional placement supports for those newly entering the workforce and those seeking to advance in their careers. Participants will make a three-year commitment of service, in the new professional title, to Medicaid providers that serve at least 30 percent Medicaid members and/or uninsured individuals.

CareerSource Florida

Federal and state workforce grants to support job training, employment services, and career development for Florida job seekers, including adults, dislocated workers, and youth.

National Park Service

The overall mission of the NPS Centennial Volunteer Ambassador Program is to support park units service-wide in expanding volunteerism, service-learning, and community engagement programs and activities to new audiences and communities. The program will allow the NPS to help develop the next generation of lifelong conservation stewards and ensure a skilled and diverse workforce pipeline, through work &amp; training opportunities for young adults and veterans. The program is also designed to inspire young adults and veterans (18-35 years old) from diverse backgrounds who are service focused to aspire for careers of conservation stewardship through exposure to the many difference career and leadership developmental opportunities. NPS will provide the necessary training, career development and education so that program participants can be effective and supported in their role. The Centennial Volunteer Ambassador Program will help to build a pathway which lead to a career with the NPS and/or will assist in creating the next generation of conservation stewards. SCA will provide support for 115 Centennial Volunteer Ambassadors through recruitment, enrollment, housing, transportation, training, uniform/gear; background check, Risk Management, FICA, and program support.

Transportation Department

The Maritime Administrator, after consultation with the United States Coast Guard, may designate a domestic maritime training or education entity as a Center of Excellence for Domestic Maritime Workforce Training and Education (CoE). MARAD's CoE Program focuses on entities other than Federal and State maritime academies that support the needs of the domestic maritime community. CoEs are key to building the maritime workforce and providing the necessary infrastructure for the United States to mobilize the required workforce in times of national need. Designations recognize the critical role these entities play in recruiting and training our Nation's maritime workforce and restoring America's maritime dominance. A CoE designation is valid for a period of five years. This notice solicits applications from eligible entities for the 2026 cycle of CoE designation. The notice also updates CoE Program policy to align with Executive Order (E.O.) 14151, Ending Radical and Wasteful Government DEI Programs and Preferencing, and announces that MARAD has terminated action on the 2024 application cycle, which was no longer in compliance with current Administration policy.

U.S. National Science Foundation

The Centers of Research Excellence in Science and Technology (CREST) program provides support to enhance the research capabilities of minority-serving institutions (MSIs) through the establishment of centers that effectively integrate education and research. CREST promotes the development of new knowledge, enhancements of the research productivity of individual faculty, and an expanded presence of students who are members of groups underrepresented in science, technology, engineering, and mathematics (STEM) disciplines. The CREST Postdoctoral Research Program (CREST-PRP) awards are part of the overarching CREST program and provide two years of support for research experience and training for early career scientists at active CREST Centers. The goal of the CREST-PRP awards isto increase the workforce presence of individuals from groups underrepresented in STEM fields. CREST-PRP awards recognize investigators with significant potential and provide them with research experiences that broaden perspectives, facilitate interdisciplinary interactions, and prepare CREST-PRP scholars for positions of leadership within the scientific community. Postdoctoral scholars conduct research on topics aligned with the research focus of the host CREST Center. The awards are also designed to provide active mentoring to the postdoctoral scholars by thescientific mentorwho, in turn, will benefit from the incorporation of these talented scientists into their research groups. Proposals must be submitted by individual postdoctoral candidates. However, if an award is recommended, the award will be transferred to the host institution where the postdoctoral scholar will be named as the PI. The award will be issued to the host institution as a regular research award, and the award will be administered by the host institution. Women, veterans, persons with disabilities, and members of groups underrepresented in STEM are especially encouraged to apply.

Employment and Training Administration

To advise State Workforce Agencies, or agencies designated by Governors as "Cooperating State Agencies" (CSAs) (also jointly referred to as "states") of the "by request" process and associated deadlines for receiving FY 2026 TAA Program TaOA funds. Questions regarding this Unemployment Insurance Program Letter (UIPL) may be emailed to Chanta Ferrell (ferrell.chanta@dol.gov).