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Joe Brazil Legacy Coalition

The Joe Brazil Legacy Coalition is bringing jazz musicians together to celebrate the Honorable Joseph Brazil for what would have been his 94th. birthday. This event will be a reunion of Mr. Brazil's students and alumni from his jazz music programs in Seattle at Garfield High School, the University of Washington, and the Black Academy of Music. This event will be from 9:30 a.m. to 9:00 p.m. on August 21, 2021 at the Langston Hughes Cultural Arts Center located at 104 17th Ave S. This project will be completed by October 29, 2021.

Montgomery County MD / State of Maryland

Other Legislative Initiatives

Montgomery County MD / State of Maryland

FY24 Preauthorizations-House and Senate

Wa Na Wari

The BLOOM Food Justice Series will bring together urban farmers, community gardeners, naturalists, young adults, city staff and the broader community to consider food justice and food sovereignty in Seattle. This summer, 12 BIPOC youth ages 18-25 will participate in a training program with a curriculum spanning Indigenous knowledge systems, Black Liberation, urban farming practices, plant medicines, the healing arts, ways to combat environmental racism and much more. The anticipated project completion date is November 30, 2021.

Bloomberg Philanthropies

Grants for arts organizations piloting innovative public engagement, technology integration, and community access programs.

Blue Grass Community Foundation

Blue Grass Community Foundation ($200M in assets) supports nonprofits in KY through grants focused on education, community development, health, arts. Awards range from $1,000 to $50,000.

NHLBI - National Heart Lung and Blood Institute

PROJECT SUMMARY/ABSTRACT Bronchiolization of alveoli – replacement of gas-exchange epithelium by airway-like cells – is the project’s key focus because it cripples pulmonary function in pulmonary fibrosis. The long-term goal is to identify and pharmacologically target stress- and glycosylation-driven pathways that destabilize alveolar identity, thereby advancing therapies that align with NIH’s mission to reduce morbidity from chronic lung disease. Guided by three Specific Aims, the applicant will (1) pinpoint the integrated-stress-response kinase triggering ATF4 activation, (2) determine whether ISR-ATF4 signaling is necessary and sufficient for bronchiolization, and (3) establish how ATF4-induced FUT1-mediated α1,2-fucosylation suppresses BMP4 signaling and shifts airway-alveolar cell competition. The research design combines phospho-proteomics, genetic and small-molecule kinase blockade, conditional gene deletion, lineage-traced organoids, single-cell RNA-sequencing, quantitative histology, and lung-function testing to deliver mechanistic clarity and druggable nodes. The fellowship training plan integrates advanced coursework in single-cell genomics, glycobiology, and organoid engineering with bi-weekly mentor meetings, grant-writing workshops, and LungMAP consortium bootcamps to cultivate technical breadth, analytical rigor, and leadership. The training environment – the UC San Diego Lung Center, epigenomics and imaging cores, glycobiology facility, and multidisciplinary fibrosis network – provides state-of-the-art resources, expert consultation, and a collaborative culture that will accelerate the candidate’s development into an independent investigator.

European Commission - HORIZON

Boosting creative startups for disruptive innovation. Call: Culture, Creativity and Inclusive Society 2026. Programme: HORIZON. Keywords: Business and Management, Business models, Business plan, Company valuation, Creativity management, Economics, Econometrics, Entrepreneurship, Incubator companies, Innovation methodologies, Innovation policy, Innovation systems, Investment readiness, Knowledge and Technology transfer, Leadership development, New business opportunities, Performing arts studies (Musicology, Theater science, Dramaturgy), Private investment, Social sciences, interdisciplinary, Spin-off companies, Start-up companies, Studies on Film, Radio and Television, Technology commercialisation. Open call from the EU Funding & Tenders Portal.

Borealis Light Arts Collective

The Borealis Light Arts Collective will host the Borealis Festival of Light, a display of light art that will take place on October 11, 12, and 13, 2018 from 5 pm - 9 pm nightly at Lake Union Park located at 860 Terry Ave N. The festival will feature light art installations, multi-media projections on surrounding structures, and performance art.

Bowdoin Place Condos

The Bowdoin Place community group will use artwork to beautify utility boxes located at Fremont Ave N and N. 39th St to enhance the visual appeal of the utility boxes that are a frequent target of graffiti and vandalism. A community celebration will be held in October 2017 to view the completed utility box artwork.

NIAAA - National Institute on Alcohol Abuse and Alcoholism

BRAIN METABOLISM AND ALCOHOL USE DISORDER ABSTRACT Glucose through glycolysis and the Tricarboxylic Acid (TCA) cycle in the mitochondria supplies energy to the brain. Glycolysis disfunction has been associated with neurodegeneration, stress and depression. Moreover, Volkow and colleagues reported that glucose metabolism is reduced in the brain of human subjects suffering from alcohol use disorder (AUD). Using animal models of AUD, we found that the kinase mTORC1 plays a crucial role in mechanisms underlying excessive alcohol seeking and drinking, relapse, and alcohol habit and reward. mTORC1 is activated by alcohol in the nucleus accumbens (NAc), and specifically in dopamine D1 receptor expressing (D1+) NAc neurons. We recently found that the activation of mTORC1 in the NAc of mice in response to long-term of intermittent access to 20% alcohol 2-bottle choice (IA20%2BC) promotes the translation of microRNA (miR) machinery transcripts in D1+ NAc neurons which in turn promotes the expression of a number of miRs including the miR, miR34a-5p. We further showed that alcohol-mediated activation of mTORC1 in D1+ NAc neurons represses the translation of several transcripts including Aldolase A a crucial enzyme in glycolysis which we found to be a target of miR34a-5p. We discovered that Aldolase A translation repression in D1+ NAc neurons is accompanied by the attenuation of NAc Lactate, the end product of glycolysis. We also found that metabolites in the mitochondria TCA cycle are attenuated in the NAc by IA20%2BC. Finally, we showed that overexpression of miR34a-5p increases whereas systemic administration of L-Lactate reduces heavy alcohol intake. Together, these data suggest that the pathway consisting of: mTORC1­/miR34a5p­/Aldolase A¯, is activated by alcohol in the NAc D1+ neurons, which inhibits glycolysis and promotes heavy alcohol use. Here, we plan to test the overall hypothesis that alcohol alters glycolysis, energy production and the metabolic signature in the Nac, which in turn contribute to behavioral phenotypes associated with AUD. We will utilize state of the art tools in combination with behavioral paradigms in female and male mice to address the following aims: Aim 1 will focus on glycolysis and examine cell-type specificity, cellular compartmentalization and molecular, and behavioral consequences of alcohol-mediated attenuation of glycolysis. Aim 2 will focus on alcohol interaction with the mitochondria in the Nac and will examine ATP levels and mitochondria morphology in mice with a history of alcohol use. In Aim 3, we will conduct a large scale comprehensive transcriptomic/metabolomic (multiomic) study to uncover the metabolic map which includes metabolites and metabolic enzymes in the Nac of mice consuming alcohol. This is a groundbreaking discovery proposal that will uncover alcohol-dependent metabolic adaptations in the brain. Results generated from the project will lay the foundation for a new dimension in alcohol research in the CNS.

NIDA - National Institute on Drug Abuse

Methamphetamine (METH) remains a major public health challenge for the clinical management of people with HIV (PWH) and for controlling HIV transmission. METH can increase HIV transcription, alter immune responses, and disrupt immunometabolism and the blood-brain barrier (BBB). These and other processes combine to worsen brain health, including cognition, mood, and impulsivity. Because PWH with active METH use disorder (aMUD) often struggle with medical adherence, some do not achieve durable viral suppression with oral antiretroviral therapy (ART). Advances in long-acting injectable (LAI)-ART and medication-assisted treatment (MAT) for addiction could change this. The combination of LAI-ART and MAT that includes LAI naltrexone could improve the durability of viral suppression and reduce METH use in PWH with aMUD, which creates an opportunity to investigate the brain health effects of these changes. Addressing this requires a multidisciplinary framework. We propose to leverage these advances and integrate methods from implementation science, pharmacology, virology, immunology, and clinical and basic neuroscience to understand how LAI-ART and MAT for aMUD interact to alter brain health and its biological underpinnings. The Brain-Focused Research on Antiretrovirals and Methamphetamine (Brain-FRAMe) program will pursue a single, transformative goal: to improve the clinical care and brain health of PWH with aMUD. The proposed research will be organized into three subgoals: Clinical Implementation, Brain Health Phenotyping, and Biological Mechanisms. Investigators will form four teams that will study the same participants over 52 weeks from different perspectives. The Clinical Implementation Team will deploy and evaluate the implementation of LAI-ART and MAT in PWH with aMUD in a primary care HIV clinic. The Neurobehavioral Phenotyping Team will characterize the neuromedical, neurocognitive, and psychiatric changes that result from LAI-ART and MAT. The Biophenotyping and Pharmacology Team will assess effects of METH and MAT on ART pharmacokinetics as well as changes in the HIV reservoir and proteomic and transcriptomic profiles in blood and CSF. Using biospecimens from the same participants over time, the Basic Science Mechanisms Team will interrogate targeted biological mechanisms that underlie the effects of aMUD, LAI-ART, and MAT, such as BBB integrity, immunometabolism, and immune competence. The robust and reproducible methods used by all teams will generate data that will be analyzed individually and in aggregate by the Data Integration and Analysis Group. The Scientific Program Coordinator and Contact PI will work with the MPIs and program staff to coordinate all aspects of the program, monitor progress, foster communication, curate data and biospecimens, convene advisory boards, and assure synergy and integration. Using these and other innovative methods, Brain-FRAMe will achieve within five years its goal of transforming the clinical care and brain health of this highly vulnerable group of people, which should also reduce new HIV infections in our community.

NIGMS - National Institute of General Medical Sciences

Abstract Western Washington University (WWU) seeks BRE-SPAD funding to strengthen its research infrastructure and expand faculty and student engagement in biomedical research. As a Predominantly Undergraduate Institution (PUI) with a strong commitment to liberal arts education, WWU has seen steady growth in research activities in the past several years. Research expenditures have almost doubled in less than a decade from $8.5 million in 2014 to $15.9 million in 2023. Yet, WWU’s biological, biomedical, and health sciences R&D expenditures were only $864,000, representing just 5% of total institutional R&D expenditures. WWU will use BRE-SPAD funding to address several institutional challenges, including high teaching loads, lack of key research equipment, limited pre- and post-award administrative support, no central system for recruiting students into undergraduate research opportunities, and a lack of dedicated research development programming. The proposed SPAD initiative at WWU will enhance research capacity through the following specific aims: 1) Improve sponsored programs administration capacity by hiring a new research administrator, training all pre- and post-award staff on NIH proposal submission and award management best practices, and learning from an external evaluation process to improve overall research administration and research development services. 2) Enhance WWU’s research environment by establishing the Viking Biomedical Research Institute (VBR), hiring a program manager, purchasing key biomedical research equipment and supplies, training biomedical faculty in effective NIH research design and proposal writing, incentivizing faculty to develop new course- based undergraduate research experiences (CURES), and creating a centralized mentoring hub for students interested in pursuing biomedical research. and 3) Launch a pilot research project funding program by offering pilot awards, providing faculty release time to focus on research activities, providing resources for undergraduate student participation in the research projects, and enabling faculty to collect data and conduct preliminary analyses that will make subsequent NIH proposals more competitive. By achieving these aims, WWU expects to catalyze a significant increase in the number of faculty – and faculty from a wider range of disciplines – who submit NIH proposals, growth in biomedical research expenditures, increased student participation in biomedical research, an increase in the number of students who graduate with biomedical and health-related degrees and qualifications to enter the regional biomedical workforce, and the establishment of a sustainable and robust biomedical research enterprise.

NICHD - Eunice Kennedy Shriver National Institute of Child Health and Human Development

PROJECT ABSTRACT Sub-Saharan Africa (SSA), a region dominated by low-resource communities and relatively poor families, is experiencing rising HIV prevalence among adolescents and youth (AY). Household economic hardships heighten the risk for AY’s engaging in health-compromising behaviors and their poor engagement with care. This increases their risk for contracting and transmitting HIV and non-adherence to ART treatment. Economic empowerment (EE) interventions have demonstrated substantial promise in reducing HIV-related risk-taking behaviors, and improving ART treatment adherence and mental health outcomes. Based on 10+ years of research utilizing savings-led EE interventions focused on HIV prevention, care and support for AY affected by HIV [AYaAIDS] (including AY living with HIV [AYLHIV]; and AY orphaned by AIDS [AYoAIDS] in SSA, our group has demonstrated the effectiveness of a multi-component EE intervention, Bridges, in four NIH-funded randomized control trials (RCT) in Uganda (R01 HD070727, R01HD074949, R34MH081763, R01MH113486), and one foundation-funded study in Kenya. Bridges involves: 1) financial literacy training (FLT) and mentorship; 2) family income-generating activities (IGA); and 3) incentivized savings via a matched Youth Development Account (YDA). Bridges has demonstrated robust effects on HIV-related risk-taking behaviors, ART adherence, mental health, psychosocial outcomes, educational achievement, family economics, and family cohesion. Yet, scaling EE interventions has been a challenge, signaling the need to identify and test scale-up strategies and examine determinants of implementation and sustainment. In Bridges2Scale, we will compare two multifaceted strategies (standard vs enhanced) for scaling Bridges in a two-arm Hybrid III effectiveness-implementation cluster RCT. The standard implementation strategy has been applied in our prior RCTs and involves educational meetings that prepare staff to deliver Bridges with minimal disruption to site workflow. This will be compared to an enhanced strategy that will be developed using Implementation Mapping. We will use the public school system to recruit 1440 AYaAIDS (ages 13-17 years) from 48 schools in the Greater Masaka region of Uganda, a region with 11.7% HIV prevalence. Schools will be the unit of randomization (n=24 schools per arm; n=720 students per arm). Four specific aims guide our study: Aim 1. Compare the implementation effectiveness of the standard implementation strategy vs. an enhanced implementation strategy; Aim 2. Determine the clinical effectiveness of Bridges implemented via a standard vs. enhanced implementation strategy; Aim 3. Explore implementation processes, mechanisms, and determinants; and Aim 4. Compare the cost and cost-effectiveness of the two implementation strategies. The study will address a critical challenge: how to best support the implementation, scale-up, and sustainment of EE interventions, which have been proven to be highly efficacious in improving youth-focused HIV prevention, care, and support outcomes, but are yet to be widely scaled up.

City Of Bristol

Priority

City Of Bristol

Priority

Friends of Hiawatha

The Friends of Hiawatha will engage in street activation thru art at 843 Hiawatha Pl S that will include the side streets of S. Charles and Dearborn Ave corners. The activation includes tree lighting for beautification, and culminating with a winter celebration on February 7, 2025 on First Friday Artwalk. The event is free and open to the public.

Fish and Wildlife Service

The National Wildlife Refuge Association proposes to work with the National Wildlife Refuge System through a Cooperative Agreement to invest $1 million of construction funding in four urban refuges. The refuges have been selected because they are developing innovative urban outreach programs, have a level of readiness to be able to maximize capital investments, and are in cities that America looks toward to set trends. The Refuge Association will assist the Service in developing state-of-the-art infrastructure projects at each of the four refuges, and the Association would seek to complement capital investments by the Service with capital and program capacity funding to bring these facilities alive with programs for urban families experiencing our National Wildlife Refuge System and the mission of the USFWS.

The Eli's Park Project

Initiated and designed by the community it will serve, the Eli's Park Project at the Burke Gilman Playground Park, located at 5201 Sand Point Way NE, will renovate an underutilized green space into a park that is fully accessible to people of all ages, abilities and identities. This phase of funding will complete the art elements partially funded in the previous cycle and includes the fabrication and installation of 5 permanent art features. All contractors qualified through community hiring panels and public art calls. This project will be completed by December 30, 2022.

The Eli's Park Project

Led by Site Workshop and our design team, The Eli's Park Project will continue our partnership with Seattle Parks and Recreation in design development for the Burke-Gilman Playground Park located at 5201 Sandpoint Way NE. This phase will result in design documents including civil engineering reports and integrated art elements. This phase is estimated to be completed by February 2020.

Think Big, Wedgwood

The Think Big, Wedgewood community group, purpose for the project is to create a sense of unity in their neighborhood through art that communicates that Wedgwood welcomes all. Think Big Wedgewood will have a public design process and fabricate and hang light pole banners that will be non-commercial in nature & beautify the neighborhood. There will be roughly 25 banners along the 35th Ave business district between 75th & 95th in Wedgwood. The banners will be installed by SuperGraphics with the guidance of the Seattle Dept of Transportation Directors Pole Banner Permitting Guidelines, or the appropriate recommended contractor.

Calgary Foundation

Calgary Foundation provides grants for community well-being in the Calgary area including arts, education, environment, health, and social services.

California Arts Council

California Arts Council provides grants to support arts and cultural programming, artist fellowships, arts education, and community-based arts projects across CA.

California Arts Council

Artists in Schools (AiS) provides direct arts education experiences by placing professional artists in K-12 schools and community settings throughout California.