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View full policyUAB Precision Nutrition Clinical Center
About This Grant
ABSTRACT The reasons for individual variability in the physiologic response to dietary patterns are not well understood but hamper efforts to provide optimum diets to our population. There is an urgent need to understand the complex interaction of demographic, genetic, metabolic, behavioral, psychosocial, and environmental factors that affect the responses to dietary patterns in order to prevent and treat nutrition-related chronic diseases. The field of “precision nutrition” holds great promise for elucidating these interactions to eventually predict the optimal diet for an individual or groups of individuals. The overall objective of this application is to request additional funds for the final year of subject recruitment at the University of Alabama at Birmingham (UAB) to support meeting enrollment targets for the Nutrition for Precision Health Consortium. Due to delays in protocol development and a slow enrollment rate at the beginning of the study, additional staff effort is needed in Year 5 to increase enrollment to meet our targets. The study team will collect a wide range of physiological and metabolic data from individuals in response to free-living (module 1) and controlled diets (module 2), that will be used in analyses to determine potential predictors of response to diet. Sophisticated data methods (artificial intelligence, machine learning, mathematical modelling) will then be employed by the study group to identify the comprehensive phenotypes needed for individualizing diet prescriptions. We aim to accomplish the following two specific aims: Specific Aim 1 (module 1): Conduct an observational study of 1000 free-living individuals consuming their usual diet for 8-10 days. The physiologic responses to a standardized test meal challenge will be assessed while they are consuming their usual diet. Specific Aim 2 (module 2): Conduct a free-living controlled feeding study in 250 subjects fed three isocaloric diets varying in macronutrient composition at maintenance energy requirements. Diets are designed to elicit a wide range of responses among participants. The physiologic responses to standardized test meals and diet-specific meals will be measured at the end of each 14-day diet period. We will also collect measures of 24-hr glucose, 24-hr physical activity and sleep during each diet period. UAB, with access to >16,000 All of Us participants in Birmingham, outstanding facilities for conducting diet interventions, and an outstanding research team, can support the Nutrition for Precision Health Consortium with meeting enrollment targets with additional funds.
Grant Summary
UAB Precision Nutrition Clinical Center is a OD - NIH Office of the Director grant providing up to $1.8M for university, nonprofit, healthcare org. Applications are due 2026-11-30 (open). Check eligibility and apply with FindGrants.
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Focus Areas
Eligibility
How to Apply
Up to $1.8M
2026-11-30
- 1Confirm your organization is eligible for UAB Precision Nutrition Clinical Center from OD - NIH Office of the Director, checking organization type, location, and any population or project requirements.
- 2Gather the required documents and information, including your organization details, project plan, and budget figures.
- 3Draft your application narrative and budget addressing the funder's priorities and review criteria. FindGrants can draft each section for you to review and edit.
- 4Review every section against the requirements checklist, then export a submission-ready application pack and submit it to OD - NIH Office of the Director before the deadline.
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UAB Precision Nutrition Clinical Center: Frequently Asked Questions
Who is eligible for the UAB Precision Nutrition Clinical Center?
UAB Precision Nutrition Clinical Center is offered by OD - NIH Office of the Director and is generally open to university, nonprofit, healthcare org. It is open to organizations nationwide unless the funder specifies otherwise. Review the specific eligibility terms before applying, since funders set their own requirements around organization type, location, and the population or project being served.
How much funding does the UAB Precision Nutrition Clinical Center provide?
UAB Precision Nutrition Clinical Center provides up to $1.8M per award from OD - NIH Office of the Director. Actual award sizes depend on the scope of your project, available program funds, and the number of applicants, so build a budget that reflects realistic, allowable costs rather than the maximum figure.
When is the UAB Precision Nutrition Clinical Center deadline?
Applications for UAB Precision Nutrition Clinical Center are due 2026-11-30 (open). Because deadlines can change, verify the date with the funder, OD - NIH Office of the Director, and give yourself enough time to prepare a complete, competitive application before the close date.
How do you apply for the UAB Precision Nutrition Clinical Center?
To apply for UAB Precision Nutrition Clinical Center, confirm your eligibility, gather the required documents, and prepare a narrative and budget that address the funder's priorities. FindGrants guides you step by step and can draft each section, then exports a submission-ready application pack for this grant from OD - NIH Office of the Director.