BEACON: Building Evidence for Optimal Genomic Screening Implementation in Primary Care
About This Grant
PROJECT SUMMARY Background: Population Genomic Screening (PGS) offers a transformative opportunity to identify millions of individuals with inherited risks for cancer, cardiovascular disease, and other conditions, yet it is not commonly integrated into primary care workflows, and most providers are unfamiliar with its use. Despite rapid growth in PGS programs, most remain research-based or institutionally supported, limiting their scalability in routine healthcare. Without standardized guidelines or strategies for implementation, the full potential of PGS to improve population health remains untapped. Integrating PGS into primary care offers an opportunity to expand the reach of genomic screening, particularly for populations in resource-limited settings. Goal: The BEACON project aims to implement and evaluate PGS in primary care settings across South Carolina to expand the reach of genomic screening and improve health outcomes by focusing on CDC Tier 1 conditions, chronic kidney disease, and inherited cardiomyopathies. Methods: Aim 1: We will prepare for PGS implementation by conducting two rounds of Community Engagement Studios with patients, providers, and other stakeholders to refine workflows, develop implementation strategies, and design educational materials. Aim 2: We will implement PGS at 10 primary care sites in South Carolina, piloting the workflow with 100 patients before scaling to 5,000 patients. We will evaluate outcomes related to reach, effectiveness, adoption, and implementation using EHR data, surveys, and interviews. Aim 3: We will sustain and scale PGS by creating a framework of best practices, informed by ongoing adaptations, and disseminate this information across South Carolina and nationally through the PGS Network. Innovation and Impact: BEACON will generate critical evidence for integrating PGS into primary care settings and improve health outcomes by ensuring reach to populations in limited-resource environments. Through collaboration with the national PGS Network, we will create scalable, sustainable workflows. This project will advance precision public health and set the standard for PGS implementation across various populations and healthcare systems.
Grant Summary
BEACON: Building Evidence for Optimal Genomic Screening Implementation in Primary Care is a NHGRI - National Human Genome Research Institute grant providing up to $664K for university, nonprofit, healthcare org. Applications are due 2031-03-31 (open). Check eligibility and apply with FindGrants.
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Focus Areas
Eligibility
How to Apply
Up to $664K
2031-03-31
- 1Confirm your organization is eligible for BEACON: Building Evidence for Optimal Genomic Screening Implementation in Primary Care from NHGRI - National Human Genome Research Institute, checking organization type, location, and any population or project requirements.
- 2Gather the required documents and information, including your organization details, project plan, and budget figures.
- 3Draft your application narrative and budget addressing the funder's priorities and review criteria. FindGrants can draft each section for you to review and edit.
- 4Review every section against the requirements checklist, then export a submission-ready application pack and submit it to NHGRI - National Human Genome Research Institute before the deadline.
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BEACON: Building Evidence for Optimal Genomic Screening Implementation in Primary Care: Frequently Asked Questions
Who is eligible for the BEACON: Building Evidence for Optimal Genomic Screening Implementation in Primary Care?
BEACON: Building Evidence for Optimal Genomic Screening Implementation in Primary Care is offered by NHGRI - National Human Genome Research Institute and is generally open to university, nonprofit, healthcare org. It is open to organizations nationwide unless the funder specifies otherwise. Review the specific eligibility terms before applying, since funders set their own requirements around organization type, location, and the population or project being served.
How much funding does the BEACON: Building Evidence for Optimal Genomic Screening Implementation in Primary Care provide?
BEACON: Building Evidence for Optimal Genomic Screening Implementation in Primary Care provides up to $664K per award from NHGRI - National Human Genome Research Institute. Actual award sizes depend on the scope of your project, available program funds, and the number of applicants, so build a budget that reflects realistic, allowable costs rather than the maximum figure.
When is the BEACON: Building Evidence for Optimal Genomic Screening Implementation in Primary Care deadline?
Applications for BEACON: Building Evidence for Optimal Genomic Screening Implementation in Primary Care are due 2031-03-31 (open). Because deadlines can change, verify the date with the funder, NHGRI - National Human Genome Research Institute, and give yourself enough time to prepare a complete, competitive application before the close date.
How do you apply for the BEACON: Building Evidence for Optimal Genomic Screening Implementation in Primary Care?
To apply for BEACON: Building Evidence for Optimal Genomic Screening Implementation in Primary Care, confirm your eligibility, gather the required documents, and prepare a narrative and budget that address the funder's priorities. FindGrants guides you step by step and can draft each section, then exports a submission-ready application pack for this grant from NHGRI - National Human Genome Research Institute.