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View full policy400 MHz NMR Spectrometer
About This Grant
Project Description We request $450,305 to acquire a JEOL 400 MHz NMR spectrometer with a shielded magnet, 2-channel console, ROYAL HFX probe and autosampler to support cutting-edge synthetic chemical biology research at the University of Kansas (KU). The requested instrument will serve 15 highly active research groups, including three NIH-funded major users (Bloom, Farrell, and Sathyamoorthi) and 12 additional investigators, most of whom are also NIH-funded. This 400 MHz NMR will be housed in a long-established university-wide core facility with a strong track record for cost recovery, user training and instrument upkeep. The requested instrument will be integrated into the recently installed helium-recovery system, which will recycle over 85% of the liquid helium consumed during normal operation of the superconducting magnet and the gaseous helium expelled during periodic refills of the magnet dewar, significantly reducing the long-term operating costs and environmental impact. Based on current and projected needs, the spectrometer is expected to operate at 80% capacity. NIH-funded researchers will account for over 65% of total usage, with the three major users comprising more than half. This high utilization underscores the urgent need for a modern, reliable platform to support KU’s biomedical research. Currently, investigators rely on two aging 400 MHz NMR spectrometers, both over 20 years old, with obsolete components and growing maintenance challenges. Downtime and limited capabilities impose major delays and opportunity costs on research, despite the efforts of the highly skilled staff. Continued dependence on these outdated systems jeopardizes ongoing and future NIH- supported research. This proposal is driven by the critical need to sustain and advance KU’s synthetic chemical biology efforts. The new NMR spectrometer will directly support transformative research, including in a) the development of next-generation peptide therapeutics with enhanced stability, cell permeability, and reduced metabolic degradation; b) the design of novel chemical probes to identify neglected carbohydrate- binding proteins and better understand their roles in biology and disease; and c) the improvement of synthetic methodology for the preparation of novel anti-infective natural products to reduce human morbidity and mortality. The proposed instrument will be a vital asset to KU’s biomedical research enterprise, accelerating discovery and enhancing NIH-funded investigations in health-related chemical biology.
Grant Summary
400 MHz NMR Spectrometer is a OD - NIH Office of the Director grant providing up to $450K for university, nonprofit, healthcare org. Applications are due 2027-05-14 (open). Check eligibility and apply with FindGrants.
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Focus Areas
Eligibility
How to Apply
Up to $450K
2027-05-14
- 1Confirm your organization is eligible for 400 MHz NMR Spectrometer from OD - NIH Office of the Director, checking organization type, location, and any population or project requirements.
- 2Gather the required documents and information, including your organization details, project plan, and budget figures.
- 3Draft your application narrative and budget addressing the funder's priorities and review criteria. FindGrants can draft each section for you to review and edit.
- 4Review every section against the requirements checklist, then export a submission-ready application pack and submit it to OD - NIH Office of the Director before the deadline.
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400 MHz NMR Spectrometer: Frequently Asked Questions
Who is eligible for the 400 MHz NMR Spectrometer?
400 MHz NMR Spectrometer is offered by OD - NIH Office of the Director and is generally open to university, nonprofit, healthcare org. It is open to organizations nationwide unless the funder specifies otherwise. Review the specific eligibility terms before applying, since funders set their own requirements around organization type, location, and the population or project being served.
How much funding does the 400 MHz NMR Spectrometer provide?
400 MHz NMR Spectrometer provides up to $450K per award from OD - NIH Office of the Director. Actual award sizes depend on the scope of your project, available program funds, and the number of applicants, so build a budget that reflects realistic, allowable costs rather than the maximum figure.
When is the 400 MHz NMR Spectrometer deadline?
Applications for 400 MHz NMR Spectrometer are due 2027-05-14 (open). Because deadlines can change, verify the date with the funder, OD - NIH Office of the Director, and give yourself enough time to prepare a complete, competitive application before the close date.
How do you apply for the 400 MHz NMR Spectrometer?
To apply for 400 MHz NMR Spectrometer, confirm your eligibility, gather the required documents, and prepare a narrative and budget that address the funder's priorities. FindGrants guides you step by step and can draft each section, then exports a submission-ready application pack for this grant from OD - NIH Office of the Director.