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Comprehensive protein stability platform

OD - NIH Office of the Director

open
OpenLast verified: 2026-06-18

About This Grant

The proposed comprehensive protein stability platform will serve multiple major users in assessing the properties of protein systems associated with immunomodulation, post translational modification effects, general receptor-ligand interactions, phase separation and condensates, medicinal chemistry screening, and translational therapeutics development. The proposed instrument combines full-spectral fluorescence monitoring, with dynamic light scattering (DLS) and static light scattering (SLS) with plate reading, sealable optical plates for thermal cycling, and full automation and data reduction. This will expand the assessment of stability and component interactions by the six major users and others for the NIH supported basic and translational research at Einstein funded through four Institutes. In the long term, the new available platform is expected to improve and expand the tools available for ligand screening, optimization of targets for structural biology investigations (XRC, NMR, CEM), and investigation of quaternary, quinary, and phase structural features in a systematic and reproducible manner in multi-channel mode on a single instrument. The instrument will be housed in a core facility with skilled and experienced management.

Grant Summary

Comprehensive protein stability platform is a OD - NIH Office of the Director grant providing up to $200K for university, nonprofit, healthcare org. Applications are due 2027-05-14 (open). Check eligibility and apply with FindGrants.

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Focus Areas

health research

Eligibility

universitynonprofithealthcare org

How to Apply

Funding Range

Up to $200K

Deadline

2027-05-14

Complexity
Medium
  1. 1Confirm your organization is eligible for Comprehensive protein stability platform from OD - NIH Office of the Director, checking organization type, location, and any population or project requirements.
  2. 2Gather the required documents and information, including your organization details, project plan, and budget figures.
  3. 3Draft your application narrative and budget addressing the funder's priorities and review criteria. FindGrants can draft each section for you to review and edit.
  4. 4Review every section against the requirements checklist, then export a submission-ready application pack and submit it to OD - NIH Office of the Director before the deadline.
This record is a past award, contract, or funder profile — useful for research, but not an open grant application. Check the original source for current opportunities from this funder.

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Comprehensive protein stability platform: Frequently Asked Questions

Who is eligible for the Comprehensive protein stability platform?

Comprehensive protein stability platform is offered by OD - NIH Office of the Director and is generally open to university, nonprofit, healthcare org. It is open to organizations nationwide unless the funder specifies otherwise. Review the specific eligibility terms before applying, since funders set their own requirements around organization type, location, and the population or project being served.

How much funding does the Comprehensive protein stability platform provide?

Comprehensive protein stability platform provides up to $200K per award from OD - NIH Office of the Director. Actual award sizes depend on the scope of your project, available program funds, and the number of applicants, so build a budget that reflects realistic, allowable costs rather than the maximum figure.

When is the Comprehensive protein stability platform deadline?

Applications for Comprehensive protein stability platform are due 2027-05-14 (open). Because deadlines can change, verify the date with the funder, OD - NIH Office of the Director, and give yourself enough time to prepare a complete, competitive application before the close date.

How do you apply for the Comprehensive protein stability platform?

To apply for Comprehensive protein stability platform, confirm your eligibility, gather the required documents, and prepare a narrative and budget that address the funder's priorities. FindGrants guides you step by step and can draft each section, then exports a submission-ready application pack for this grant from OD - NIH Office of the Director.