Clinical Decision Support for Early Detection of Relapse Risk in Adolescents with Substance Use Disorders
About This Grant
PROJECT ABSTRACT Over 60% of adolescents with substance use disorders relapse within 90 days of completing treatment, largely due to fragmented data, delayed intervention, and lack of adolescent-specific clinical guidelines. This Phase I SBIR project aims to develop and validate the technical feasibility of LEVL, a novel clinical decision support (CDS) system designed specifically for early detection of relapse risk among adolescents. LEVL integrates physiological markers (heart rate, heart rate variability, sleep), behavioral data, and environmental context into an adaptive, FHIR-compliant platform that proactively alerts clinicians when elevated relapse risk is detected. The platform also features an adolescent-facing mobile application to support timely interventions and self-management. The primary goal of this Phase I study is technical feasibility, establishing the prototype’s usability, clinician adoption, and preliminary validation of the predictive risk model. Clinical predictive validity and direct clinical effectiveness in reducing relapse will be rigorously evaluated in future Phase II trials. This study will use a structured Delphi process for expert consensus on biomarkers, proprietary analytics for predictive relapse risk detection, iterative usability testing, and a 90-day feasibility trial to refine the prototype. Adolescents experiencing untreated or recurrent SUD may incur lifetime healthcare expenditures exceeding $30,000–$40,000, making early intervention a valuable cost-savings strategy. Early identification and proactive intervention have strong potential to significantly reduce healthcare costs associated with relapse. By enabling clinicians to intervene earlier through proactive alerts, LEVL aligns with federal healthcare priorities emphasizing evidence-based care, targeted cost-savings, and early intervention in substance use disorders.
Grant Summary
Clinical Decision Support for Early Detection of Relapse Risk in Adolescents with Substance Use Disorders is a NIDA - National Institute on Drug Abuse grant providing up to $400K for university, nonprofit, healthcare org. Applications are due 2027-05-31 (open). Check eligibility and apply with FindGrants.
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Focus Areas
Eligibility
How to Apply
Up to $400K
2027-05-31
- 1Confirm your organization is eligible for Clinical Decision Support for Early Detection of Relapse Risk in Adolescents with Substance Use Disorders from NIDA - National Institute on Drug Abuse, checking organization type, location, and any population or project requirements.
- 2Gather the required documents and information, including your organization details, project plan, and budget figures.
- 3Draft your application narrative and budget addressing the funder's priorities and review criteria. FindGrants can draft each section for you to review and edit.
- 4Review every section against the requirements checklist, then export a submission-ready application pack and submit it to NIDA - National Institute on Drug Abuse before the deadline.
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Clinical Decision Support for Early Detection of Relapse Risk in Adolescents with Substance Use Disorders: Frequently Asked Questions
Who is eligible for the Clinical Decision Support for Early Detection of Relapse Risk in Adolescents with Substance Use Disorders?
Clinical Decision Support for Early Detection of Relapse Risk in Adolescents with Substance Use Disorders is offered by NIDA - National Institute on Drug Abuse and is generally open to university, nonprofit, healthcare org. It is open to organizations nationwide unless the funder specifies otherwise. Review the specific eligibility terms before applying, since funders set their own requirements around organization type, location, and the population or project being served.
How much funding does the Clinical Decision Support for Early Detection of Relapse Risk in Adolescents with Substance Use Disorders provide?
Clinical Decision Support for Early Detection of Relapse Risk in Adolescents with Substance Use Disorders provides up to $400K per award from NIDA - National Institute on Drug Abuse. Actual award sizes depend on the scope of your project, available program funds, and the number of applicants, so build a budget that reflects realistic, allowable costs rather than the maximum figure.
When is the Clinical Decision Support for Early Detection of Relapse Risk in Adolescents with Substance Use Disorders deadline?
Applications for Clinical Decision Support for Early Detection of Relapse Risk in Adolescents with Substance Use Disorders are due 2027-05-31 (open). Because deadlines can change, verify the date with the funder, NIDA - National Institute on Drug Abuse, and give yourself enough time to prepare a complete, competitive application before the close date.
How do you apply for the Clinical Decision Support for Early Detection of Relapse Risk in Adolescents with Substance Use Disorders?
To apply for Clinical Decision Support for Early Detection of Relapse Risk in Adolescents with Substance Use Disorders, confirm your eligibility, gather the required documents, and prepare a narrative and budget that address the funder's priorities. FindGrants guides you step by step and can draft each section, then exports a submission-ready application pack for this grant from NIDA - National Institute on Drug Abuse.