Enhanced Imaging using Structured Glass-Ceramic Scintillators
NIBIB - National Institute of Biomedical Imaging and Bioengineering
About This Grant
PROJECT SUMMARY The investigators’ goal is to improve image quality and reduce dose for x-ray imaging applications employing indirect flat panel detectors (I-FPDs) at high energies. The objective of this project is to develop novel structured, glass-based conversion screens that will detect x-rays with megavoltage (MV) energies more efficiently, resulting in large improvements in detective quantum efficiency (DQE). These conversion screens will be produced by unique processing methods and then evaluated for use in MV portal imaging applications and megavoltage cone-beam computed tomography (MV-CBCT). The conversion screens will be incorporated into a custom flat panel detector, where the scanning and data acquisition electronics have been removed from the path of the x-ray beam. The prototype imaging system will be exposed to a 6 MV treatment beam from a linear accelerator (LINAC). Measurements of modulation transfer function (MTF) and noise power spectrum (NPS) will be made, allowing calculation of the DQE. Phantoms, including a Las Vegas phantom for contrast-detail and parts of an Alderson Rando phantom for anatomy, will be imaged; these phantoms will reveal potential artifacts and non- uniformities that would not be evident from resolution and noise measurements. The temporal response will be measured, including afterglow in the glass scintillation pulses and lag in the prototype imaging system. Other relevant characteristics will be determined including x-ray emission spectrum, x-ray absorption coefficient, and radiation hardness. These novel conversion screens will enable increased performance in MV portal imaging, including improved soft tissue contrast and the enhancement of “beam’s-eye-view” applications such as real- time motion tracking. The proposed research could also significantly improve the low-dose performance of MV-CBCT systems. Furthermore, future refinements could lead to improvements in imaging applications using x-rays at kV energies and neutrons.
Grant Summary
Enhanced Imaging using Structured Glass-Ceramic Scintillators is a NIBIB - National Institute of Biomedical Imaging and Bioengineering grant providing up to $157K for university, nonprofit, healthcare org. Applications are due 2028-03-31 (open). Check eligibility and apply with FindGrants.
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Focus Areas
Eligibility
How to Apply
Up to $157K
2028-03-31
- 1Confirm your organization is eligible for Enhanced Imaging using Structured Glass-Ceramic Scintillators from NIBIB - National Institute of Biomedical Imaging and Bioengineering, checking organization type, location, and any population or project requirements.
- 2Gather the required documents and information, including your organization details, project plan, and budget figures.
- 3Draft your application narrative and budget addressing the funder's priorities and review criteria. FindGrants can draft each section for you to review and edit.
- 4Review every section against the requirements checklist, then export a submission-ready application pack and submit it to NIBIB - National Institute of Biomedical Imaging and Bioengineering before the deadline.
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Enhanced Imaging using Structured Glass-Ceramic Scintillators: Frequently Asked Questions
Who is eligible for the Enhanced Imaging using Structured Glass-Ceramic Scintillators?
Enhanced Imaging using Structured Glass-Ceramic Scintillators is offered by NIBIB - National Institute of Biomedical Imaging and Bioengineering and is generally open to university, nonprofit, healthcare org. It is open to organizations nationwide unless the funder specifies otherwise. Review the specific eligibility terms before applying, since funders set their own requirements around organization type, location, and the population or project being served.
How much funding does the Enhanced Imaging using Structured Glass-Ceramic Scintillators provide?
Enhanced Imaging using Structured Glass-Ceramic Scintillators provides up to $157K per award from NIBIB - National Institute of Biomedical Imaging and Bioengineering. Actual award sizes depend on the scope of your project, available program funds, and the number of applicants, so build a budget that reflects realistic, allowable costs rather than the maximum figure.
When is the Enhanced Imaging using Structured Glass-Ceramic Scintillators deadline?
Applications for Enhanced Imaging using Structured Glass-Ceramic Scintillators are due 2028-03-31 (open). Because deadlines can change, verify the date with the funder, NIBIB - National Institute of Biomedical Imaging and Bioengineering, and give yourself enough time to prepare a complete, competitive application before the close date.
How do you apply for the Enhanced Imaging using Structured Glass-Ceramic Scintillators?
To apply for Enhanced Imaging using Structured Glass-Ceramic Scintillators, confirm your eligibility, gather the required documents, and prepare a narrative and budget that address the funder's priorities. FindGrants guides you step by step and can draft each section, then exports a submission-ready application pack for this grant from NIBIB - National Institute of Biomedical Imaging and Bioengineering.