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About This Grant
Partial ophthalmoplegia due to a single cranial nerve palsy are common with an estimated 700,000 cases in the US and 15,000 new cases annually in the VA, with the most common causes being stroke and diabetes. There can also be bidirectional and total ophthalmoplegia due to multiple cranial nerve palsies, for which there is currently no effective treatment. Unresolvable diplopia is common in ophthalmoplegias, resulting in visual confusion, increased risk for falls, and reduced quality of life on par with glaucoma and AMD. Ophthalmoplegias affect many aging Veterans with neurological diseases and younger Veterans with severe polytrauma, making them a priority for VA research. We propose to reanimate the eye in ophthalmoplegias by attaching a NdFeB magnet to the eye and actuating the ocular magnet with a larger magnet fixed externally, on an eyewear temple between the ear and the eye. NdFeB are quite powerful and widely available, as they are commonly used in cell phones and toys, and therefore the safety profile is well-established. In unidirectional cases, such as 6th nerve palsy, a static magnetic force is sufficient and does not require a power source. In bidirectional or total ophthalmoplegias, a small motor will rotate the spectacle magnet to control the eye movements. Prior studies have already made calculations suggesting NdFeB actuation of the eye is possible at clinically feasible component sizes and separations, but the approach has never been pursued beyond this step. This project will move the field forward by creating a realistic eye model, design and optimizing a prototype system, and acquiring feasibility data for methods of fixing the ocular magnet 1) surgically, and 2) non-invasively via a magnetic scleral contact lens.
Grant Summary
Re-animation of the eye with neodymium actuation system is a NIH grant providing funding that varies by award for university, nonprofit, healthcare org. Applications are due 2027-09-30 (open). Check eligibility and apply with FindGrants.
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Focus Areas
Eligibility
How to Apply
Up to $0K
2027-09-30
- 1Confirm your organization is eligible for Re-animation of the eye with neodymium actuation system from NIH, checking organization type, location, and any population or project requirements.
- 2Gather the required documents and information, including your organization details, project plan, and budget figures.
- 3Draft your application narrative and budget addressing the funder's priorities and review criteria. FindGrants can draft each section for you to review and edit.
- 4Review every section against the requirements checklist, then export a submission-ready application pack and submit it to NIH before the deadline.
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Re-animation of the eye with neodymium actuation system: Frequently Asked Questions
Who is eligible for the Re-animation of the eye with neodymium actuation system?
Re-animation of the eye with neodymium actuation system is offered by NIH and is generally open to university, nonprofit, healthcare org. It is open to organizations nationwide unless the funder specifies otherwise. Review the specific eligibility terms before applying, since funders set their own requirements around organization type, location, and the population or project being served.
How much funding does the Re-animation of the eye with neodymium actuation system provide?
Re-animation of the eye with neodymium actuation system provides an amount that varies by award per award from NIH. Actual award sizes depend on the scope of your project, available program funds, and the number of applicants, so build a budget that reflects realistic, allowable costs rather than the maximum figure.
When is the Re-animation of the eye with neodymium actuation system deadline?
Applications for Re-animation of the eye with neodymium actuation system are due 2027-09-30 (open). Because deadlines can change, verify the date with the funder, NIH, and give yourself enough time to prepare a complete, competitive application before the close date.
How do you apply for the Re-animation of the eye with neodymium actuation system?
To apply for Re-animation of the eye with neodymium actuation system, confirm your eligibility, gather the required documents, and prepare a narrative and budget that address the funder's priorities. FindGrants guides you step by step and can draft each section, then exports a submission-ready application pack for this grant from NIH.